A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells (Q40419093)

20 September 2017

title

A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells (English)

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20 September 2017

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Nicoleta C Arva

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20 September 2017

Tamara R Gopen

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20 September 2017

Kathryn E Talbott

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20 September 2017

Latoya E Campbell

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20 September 2017

Agustin Chicas

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20 September 2017

David E White

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20 September 2017

Gareth L Bond

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20 September 2017

Arnold J Levine

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20 September 2017

Jill Bargonetti

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20 September 2017

language of work or name

English

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publication date

20 May 2005

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Journal of Biological Chemistry

20 September 2017

published in

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20 September 2017

volume

280

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20 September 2017

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20 September 2017

page(s)

26776-26787

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Multiple roles of the tumor suppressor p53.

20 September 2017

cites work

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A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

21 January 2018

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21 January 2018

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Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

21 January 2018

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Polyubiquitination of p53 by a ubiquitin ligase activity of p300.

21 January 2018

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Mdm2 promotes the rapid degradation of p53

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Repression of p53-mediated transcription by MDM2: a dual mechanism

21 January 2018

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

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Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

21 January 2018

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The MDM2 gene amplification database

21 January 2018

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A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

21 January 2018

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Mapping of the p53 and mdm-2 Interaction Domains

21 January 2018

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21 January 2018

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21 January 2018

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Reciprocal recruitment of DRIP/mediator and p160 coactivator complexes in vivo by estrogen receptor

21 January 2018

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Differential activation of p53 by the various adducts of mitomycin C.

21 January 2018

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Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

21 January 2018

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WAF1, a potential mediator of p53 tumor suppression

21 January 2018

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21 January 2018

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The RING domain of Mdm2 mediates histone ubiquitylation and transcriptional repression.

21 January 2018

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MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53.

21 January 2018

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p53 binds to a constitutively nucleosome free region of the mdm2 gene

21 January 2018

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Stress-dependent nucleolin mobilization mediated by p53-nucleolin complex formation

21 January 2018

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Nucleolin: a multifunctional major nucleolar phosphoprotein

21 January 2018

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M505203200

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20 September 2017

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