Pharmacological properties of neuronal TTX-resistant sodium channels and the role of a critical serine pore residue (Q40404449)

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scientific article published on 25 June 2005

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English	Pharmacological properties of neuronal TTX-resistant sodium channels and the role of a critical serine pore residue	scientific article published on 25 June 2005

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scholarly article

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Europe PubMed Central

PubMed publication ID

15981012

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20 September 2017

title

Pharmacological properties of neuronal TTX-resistant sodium channels and the role of a critical serine pore residue (English)

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Europe PubMed Central

PubMed publication ID

15981012

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20 September 2017

author name string

Andreas Leffler

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1

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Europe PubMed Central

PubMed publication ID

15981012

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20 September 2017

Raimund I Herzog

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2

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Europe PubMed Central

PubMed publication ID

15981012

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20 September 2017

Sulayman D Dib-Hajj

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3

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Europe PubMed Central

PubMed publication ID

15981012

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20 September 2017

Stephen G Waxman

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4

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Europe PubMed Central

PubMed publication ID

15981012

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20 September 2017

Theodore R Cummins

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5

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Europe PubMed Central

PubMed publication ID

15981012

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20 September 2017

publication date

25 June 2005

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Europe PubMed Central

PubMed publication ID

15981012

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20 September 2017

published in

Pfluegers Archiv

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Europe PubMed Central

PubMed publication ID

15981012

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20 September 2017

volume

451

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Europe PubMed Central

PubMed publication ID

15981012

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20 September 2017

issue

3

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Europe PubMed Central

PubMed publication ID

15981012

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20 September 2017

page(s)

454-463

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Europe PubMed Central

PubMed publication ID

15981012

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20 September 2017

cites work

A critical residue for isoform difference in tetrodotoxin affinity is a molecular determinant of the external access path for local anesthetics in the cardiac sodium channel

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local anaesthetic effects on tetrodotoxin-resistant Na+ currents in rat dorsal root ganglion neurones.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two sodium channels contribute to the TTX-R sodium current in primary sensory neurons

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity for block by saxitoxin and divalent cations at a residue which determines sensitivity of sodium channel subtypes to guanidinium toxins

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sodium channels and pain

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single serine residue confers tetrodotoxin insensitivity on the rat sensory-neuron-specific sodium channel SNS.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Slow closed-state inactivation: a novel mechanism underlying ramp currents in cells expressing the hNE/PN1 sodium channel.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

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inferred from PubMed ID database lookup

μl Na+ channels expressed transiently in human embryonic kidney cells: Biochemical and biophysical properties

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants of drug access to the receptor site for antiarrhythmic drugs in the cardiac Na+ channel

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

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inferred from PubMed ID database lookup

Phenytoin and carbamazepine: differential inhibition of sodium currents in small cells from adult rat dorsal root ganglia.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common molecular determinants of flecainide and lidocaine block of heart Na+ channels: evidence from experiments with neutral and quaternary flecainide analogues

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Residues in Na(+) channel D3-S6 segment modulate both batrachotoxin and local anesthetic affinities

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

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Molecular basis for pharmacological differences between brain and cardiac sodium channels

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophin-evoked depolarization requires the sodium channel Na(V)1.9

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular localization of an ion-binding site within the pore of mammalian sodium channels

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetrodotoxin-sensitive and tetrodotoxin-resistant Na+ channels differ in their sensitivity to Cd2+ and Zn2+.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel persistent tetrodotoxin-resistant sodium current in SNS-null and wild-type small primary sensory neurons

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants of state-dependent block of Na+ channels by local anesthetics

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in expression of two tetrodotoxin-resistant sodium channels and their currents in dorsal root ganglion neurons after sciatic nerve injury but not rhizotomy.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of Na+ channels in pain pathways

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two tetrodotoxin-resistant sodium channels in human dorsal root ganglion neurons

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Downregulation of tetrodotoxin-resistant sodium currents and upregulation of a rapidly repriming tetrodotoxin-sensitive sodium current in small spinal sensory neurons after nerve injury.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NaN/Nav1.9: a sodium channel with unique properties

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of Na(v)1.8 sodium channels to action potential electrogenesis in DRG neurons

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A tryptophan residue (W736) in the amino-terminus of the P-segment of domain II is involved in pore formation in Na(v)1.4 voltage-gated sodium channels

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent TTX-resistant Na+ current affects resting potential and response to depolarization in simulated spinal sensory neurons.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial-derived neurotrophic factor upregulates expression of functional SNS and NaN sodium channels and their currents in axotomized dorsal root ganglion neurons.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential properties of tetrodotoxin-sensitive and tetrodotoxin- resistant sodium channels in rat dorsal root ganglion neurons

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15981012

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S00424-005-1463-X

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15981012

retrieved

20 September 2017

PubMed publication ID

15981012

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15981012

retrieved

20 September 2017

 

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