The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists (Q40382410)

20 September 2017

title

The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists (English)

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Dominique Mengin-Lecreulx

20 September 2017

Ivo G Boneca

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object named as

Dominique Mengin-Lecreulx

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Mihai G Netea

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20 September 2017

Catherine Werts

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20 September 2017

Jos W. M. van der Meer

object named as

Jos W M Van Der Meer

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20 September 2017

Gerben Ferwerda

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20 September 2017

Dirk J de Jong

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20 September 2017

Muguette Jéhanno

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20 September 2017

Philippe J Sansonetti

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20 September 2017

Dana J Philpott

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20 September 2017

Sébastien Dharancy

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20 September 2017

Stephen E Girardin

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20 September 2017

language of work or name

English

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publication date

22 August 2005

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Journal of Biological Chemistry

20 September 2017

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inferred from page(s)

published in

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20 September 2017

volume

280

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20 September 2017

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20 September 2017

page(s)

35859-35867

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Lessons from Nod2 studies: towards a link between Crohn's disease and bacterial sensing

20 September 2017

cites work

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Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

21 January 2018

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Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2.

21 January 2018

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Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

21 January 2018

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Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan

21 January 2018

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An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid

21 January 2018

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

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Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases.

21 January 2018

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Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan

21 January 2018

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CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells

21 January 2018

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Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

21 January 2018

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Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis

21 January 2018

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NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

21 January 2018

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NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: implications for Crohn's disease

21 January 2018

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NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

21 January 2018

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Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

21 January 2018

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Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations

21 January 2018

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Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition

21 January 2018

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Peptidoglycan molecular requirements allowing detection by the Drosophila immune deficiency pathway

21 January 2018

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CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri.

21 January 2018

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Human Nod1 confers responsiveness to bacterial lipopolysaccharides

21 January 2018

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Structural requirements of synthetic muropeptides to synergize with lipopolysaccharide in cytokine induction

21 January 2018

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Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists

21 January 2018

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Mini-review: the role of peptidoglycan recognition in innate immunity

21 January 2018

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Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release

21 January 2018

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21 January 2018

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Mammalian peptidoglycan recognition protein binds peptidoglycan with high affinity, is expressed in neutrophils, and inhibits bacterial growth

21 January 2018

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21 January 2018

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21 January 2018

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Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-kappaB

21 January 2018

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21 January 2018

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Involvement of receptor-interacting protein 2 in innate and adaptive immune responses

21 January 2018

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RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems

21 January 2018

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hPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells

21 January 2018

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Ligand-induced dimerization of Drosophila peptidoglycan recognition proteins in vitro

21 January 2018

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Innate immune responses of epithelial cells following infection with bacterial pathogens

21 January 2018

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Reverse-phase high-pressure liquid chromatography of uridine diphosphate N-acetylmuramyl peptide precursors of bacterial cell wall peptidoglycan

21 January 2018

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Synergistic enhancement of Toll-like receptor responses by NOD1 activation

21 January 2018

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Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M504924200

1 reference

20 September 2017

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