Tamoxifen as adjuvant therapy in breast cancer. Current status (Q40385706)

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scientific article published on November 1993

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English	Tamoxifen as adjuvant therapy in breast cancer. Current status	scientific article published on November 1993

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PubMed publication ID

7507033

retrieved

20 September 2017

review article

1 reference

stated in

Europe PubMed Central

title

Tamoxifen as adjuvant therapy in breast cancer. Current status (English)

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stated in

Europe PubMed Central

PubMed publication ID

7507033

retrieved

20 September 2017

main subject

tamoxifen

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based on heuristic

inferred from title

author name string

P N Plowman

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

7507033

retrieved

20 September 2017

publication date

1 November 1993

1 reference

stated in

Europe PubMed Central

PubMed publication ID

7507033

retrieved

20 September 2017

published in

Drugs

1 reference

stated in

Europe PubMed Central

PubMed publication ID

7507033

retrieved

20 September 2017

volume

46

1 reference

stated in

Europe PubMed Central

PubMed publication ID

7507033

retrieved

20 September 2017

issue

5

1 reference

stated in

Europe PubMed Central

PubMed publication ID

7507033

retrieved

20 September 2017

page(s)

819-833

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stated in

Europe PubMed Central

PubMed publication ID

7507033

retrieved

20 September 2017

cites work

Adjuvant tamoxifen versus placebo in elderly women with node-positive breast cancer: long-term follow-up and causes of death

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endocrine effects of tamoxifen in postmenopausal breast cancer patients

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacology and clinical uses of tamoxifen

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen and arterial thrombosis

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of antiestrogens on the induction of vitellogenin and its mRNA in Xenopus laevis.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen treatment of metastatic breast cancer and antithrombin III levels

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of anti-estrogens on bone in castrated and intact female rats

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen: disease prevention or disease substitution?

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Controlled trial of tamoxifen as a single adjuvant agent in the management of early breast cancer. 'Nolvadex' Adjuvant Trial Organisation

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pilot trial to evaluate the acute toxicity and feasibility of tamoxifen for prevention of breast cancer

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear mechanisms of estrogen action. Effects of estradiol and anti-estrogens on estrogen receptors and nuclear receptor processing

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-grade endometrial carcinoma in tamoxifen-treated breast cancer patients

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged oestrogenic and mitogenic activity of tamoxifen in the ovariectomized mouse

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential role of tamoxifen in prevention of breast cancer

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiestrogens in the treatment of breast cancer

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human estrogen receptor has two independent nonacidic transcriptional activation functions

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term adjuvant tamoxifen in early breast cancer: effect on bone mineral density in postmenopausal women

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antithrombin III Level, Fibrinogen Level, and Platelet Count Changes With Adjuvant Tamoxifen Therapy

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Breast cancer in elderly women: a Cancer Research Campaign trial comparing treatment with tamoxifen and optimal surgery with tamoxifen alone. The Elderly Breast Cancer Working Party

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinopathy caused by treatment with tamoxifen in low dosage

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of oestradiol binding to mouse uterine and vaginal oestrogen receptors by triphenylethylenes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

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Bone mineral content of women receiving tamoxifen for mastalgia

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatal myocardial infarction in the Scottish adjuvant tamoxifen trial. The Scottish Breast Cancer Committee

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen retinopathy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the antitumour activity of the non-steroidal antioestrogen monohydroxytamoxifen in the DMBA-induced rat mammary carcinoma model

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen (ICI 46,474) and the human carcinoma 8S oestrogen receptor

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-oestrogens induce the secretion of active transforming growth factor beta from human fetal fibroblasts

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

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Prevention of breast cancer with tamoxifen--an update on the Royal Marsden Hospital pilot programme

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bilateral optic neuritis evolved during tamoxifen treatment

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3H-oestradiol uptake in vivo by human uterine endometrium: effect of tamoxifen (I.C.I. 46,474).

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

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Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy. 133 randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women. Early Breast Cancer Trialists' Collaborative Group

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of mouse mammary tumorigenesis by long-term tamoxifen therapy

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A controlled study of the ocular effects of tamoxifen in conventional dosage in the treatment of breast carcinoma

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen-induced remission in breast cancer by escalating the dose to 40 mg daily after progression on 20 mg daily: a case report and review of the literature

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible ocular toxicity related to tamoxifen therapy

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen as an anti-tumour agent: effect on oestrogen binding

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Risk of cancer in women receiving hormone replacement therapy

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of tamoxifen on bone mineral content in premenopausal women with breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term prevention of postmenopausal osteoporosis by oestrogen. Evidence for an increased bone mass after delayed onset of oestrogen treatment

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of Transforming Growth Factor β by the Antiestrogens Droloxifene, Tamoxifen, and Toremifene in MCF-7 Cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A non-steroidal estrogen antiagonist 1-(p-2-diethylaminoethoxyphenyl)-1-phenyl-2-p-methoxyphenyl ethanol

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clear evidence that long-term, low-dose tamoxifen treatment can induce ocular toxicity. A prospective study of 63 patients

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prospective randomised trial of tamoxifen versus surgery in elderly patients with breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor beta 1 is implicated in the failure of tamoxifen therapy in human breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of tamoxifen on spinal bone density in women with breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hormone Receptors: Studies on the Interaction of Estrogen with the Uterus

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen versus placebo: double-blind adjuvant trial in elderly women with stage II breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

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The metabolism of tamoxifen (I.C.I. 46,474). II. In female patients

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of tamoxifen on cardiovascular risk factors in postmenopausal women

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rates of bone loss in the appendicular and axial skeletons of women. Evidence of substantial vertebral bone loss before menopause

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of estrogen receptors in normal human osteoblast-like cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen receptors in human breast cancer

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen as a potential preventive agent in healthy postmenopausal women

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DES versus tamoxifen in advanced breast cancer

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Stockholm trial on adjuvant tamoxifen in early breast cancer. Correlation between estrogen receptor level and treatment effect

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The triphenylethylene drug tamoxifen is a strong liver carcinogen in the rat.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

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Bone mass in postmenopausal women after withdrawal of oestrogen/gestagen replacement therapy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

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Adjuvant tamoxifen in the management of operable breast cancer: the Scottish Trial. Report from the Breast Cancer Trials Committee, Scottish Cancer Trials Office (MRC), Edinburgh

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen is a potent "pure" anti-oestrogen in chick oviduct

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An evaluation of tamoxifen dose escalation in advanced breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

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Bone changes occurring spontaneously and caused by estrogen in early postmenopausal women: a local or generalised phenomenon?

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adjuvant tamoxifen in early breast cancer: occurrence of new primary cancers

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of covalent DNA adducts in rodents by tamoxifen.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The case for clinical trials of tamoxifen for prevention of breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-related effects of non-steroidal antioestrogens nad oestrogens on the measurement of cytoplasmic oestrogen receptors in the rat and mouse uterus

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum concentrations of tamoxifen and major metabolite during long-term nolvadex therapy, correlated with clinical response

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trial of tamoxifen at a dose of 40 mg daily after disease progression during tamoxifen therapy at a dose of 20 mg daily

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early increases in ribonucleic acid polymerase activities of dimethylbenzanthracene-induced mammary tumour nuclei in response to oestradiol-17beta and tamoxifen

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A 10-year experience of tamoxifen as primary treatment of breast cancer in 100 elderly and frail patients.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship of endogenous estrogen to bone density and bone area in normal postmenopausal women

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen retinopathy.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Breast cancer, tamoxifen, and surgery

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen and thrombosis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of transforming growth factor beta 1 in human breast cancer in vivo following tamoxifen treatment

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/7507033

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.2165/00003495-199346050-00003

1 reference

stated in

Europe PubMed Central

PubMed publication ID

7507033

retrieved

20 September 2017

Dimensions Publication ID

1018180567

0 references

PubMed publication ID

7507033

1 reference

stated in

Europe PubMed Central

PubMed publication ID

7507033

retrieved

20 September 2017

 

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