The CDK inhibitor, R-roscovitine, promotes eosinophil apoptosis by down-regulation of Mcl-1. (Q40384438)

20 September 2017

title

The CDK inhibitor, R-roscovitine, promotes eosinophil apoptosis by down-regulation of Mcl-1. (English)

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20 September 2017

Mauro M Teixeira

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20 September 2017

Rodger Duffin

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20 September 2017

Andrew E Leitch

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20 September 2017

Tara A Sheldrake

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20 September 2017

John M Hallett

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20 September 2017

Colette Meyer

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20 September 2017

Sarah Fox

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20 September 2017

Ana L Alessandri

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20 September 2017

Morag C Martin

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20 September 2017

Hugh J Brady

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20 September 2017

Ian Dransfield

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20 September 2017

Christopher Haslett

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20 September 2017

Adriano G Rossi

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20 September 2017

language of work or name

English

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publication date

18 July 2009

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20 September 2017

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20 September 2017

volume

583

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20 September 2017

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20 September 2017

page(s)

2540-2546

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

20 September 2017

1 reference

Relevance of granulocyte apoptosis to resolution of inflammation at the respiratory mucosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Corticosteroids, eosinophils and bronchial epithelial cells: new insights into the resolution of inflammation in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Eosinophil apoptosis: mechanisms and clinical relevance in asthmatic and allergic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Clinical perspectives of cell death: where we are and where to go...

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Eosinophilia in transgenic mice expressing interleukin 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Highly purified murine interleukin 5 (IL-5) stimulates eosinophil function and prolongs in vitro survival. IL-5 as an eosinophil chemotactic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Recombinant human interleukin 5 is a selective activator of human eosinophil function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Eosinophil's role remains uncertain as anti-interleukin-5 only partially depletes numbers in asthmatic airway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Eosinophils in asthma--closing the loop or opening the door?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Mepolizumab for prednisone-dependent asthma with sputum eosinophilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Mepolizumab and exacerbations of refractory eosinophilic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Pharmacological regulation of human eosinophil apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Roscovitine and other purines as kinase inhibitors. From starfish oocytes to clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Seliciclib (CYC202, R-Roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

GTP-dependent secretion from neutrophils is regulated by Cdk5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Inhibition of nuclear factor-kappaB activation un-masks the ability of TNF-alpha to induce human eosinophil apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Human circulating eosinophils secrete macrophage migration inhibitory factor (MIF). Potential role in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Structural biology. Controlling the caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Evaluation of caspase activity in apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Regulation of neutrophil apoptosis by Mcl-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Eosinophil apoptosis caused by theophylline, glucocorticoids, and macrolides after stimulation with IL-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

The differential effect of dexamethasone on granulocyte apoptosis involves stabilization of Mcl-1L in neutrophils but not in eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Targeting airway inflammation in asthma: current and future therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Pathophysiology of severe asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Regulation of eosinophil and neutrophil apoptosis--similarities and differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Critical role for caspases 3 and 8 in neutrophil but not eosinophil apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Apoptosis induced by microinjection of cytochrome c is caspase-dependent and is inhibited by Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

Apoptosis is essential for neutrophil functional shutdown and determines tissue damage in experimental pneumococcal meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2009.07.017

10.1016/J.FEBSLET.2009.07.017

21 January 2018

Identifiers

DOI

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20 September 2017

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