IKK alpha regulates estrogen-induced cell cycle progression by modulating E2F1 expression (Q40331218)

19 September 2017

title

IKK alpha regulates estrogen-induced cell cycle progression by modulating E2F1 expression (English)

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19 September 2017

Zheng Tu

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19 September 2017

Shashi Prajapati

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19 September 2017

Kyu-Jin Park

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19 September 2017

Nathan J Kelly

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19 September 2017

Yumi Yamamoto

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19 September 2017

Richard B Gaynor

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19 September 2017

language of work or name

English

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publication date

5 January 2006

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Journal of Biological Chemistry

19 September 2017

published in

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19 September 2017

volume

281

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19 September 2017

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19 September 2017

page(s)

6699-6706

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The Rb/E2F pathway and cancer

19 September 2017

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Estrogens and cell-cycle regulation in breast cancer

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A revised picture of the E2F transcriptional network and RB function

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Selective ablation of retinoblastoma protein function by the RET finger protein

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Combinatorial gene control involving E2F and E Box family members

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Differential regulation of E2F transactivation by cyclin/cdk2 complexes

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Specific regulation of E2F family members by cyclin-dependent kinases

21 January 2018

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Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint

21 January 2018

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Residues phosphorylated by TFIIH are required for E2F-1 degradation during S-phase

21 January 2018

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Regulation of E2F1 activity by acetylation

21 January 2018

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Differential regulation of E2F1 apoptotic target genes in response to DNA damage.

21 January 2018

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Specific role for p300/CREB-binding protein-associated factor activity in E2F1 stabilization in response to DNA damage

21 January 2018

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The IKK/NF-kappaB activation pathway-a target for prevention and treatment of cancer

21 January 2018

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NF-kappaB in cancer: from innocent bystander to major culprit

21 January 2018

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IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

21 January 2018

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

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Missing pieces in the NF-kappaB puzzle

21 January 2018

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Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

21 January 2018

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Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

21 January 2018

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Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

21 January 2018

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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

21 January 2018

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IKK1-deficient mice exhibit abnormal development of skin and skeleton

21 January 2018

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A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression

21 January 2018

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Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation

21 January 2018

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Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

21 January 2018

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SMRT derepression by the IkappaB kinase alpha: a prerequisite to NF-kappaB transcription and survival

21 January 2018

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Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1).

21 January 2018

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NF-kappaB: linking inflammation and immunity to cancer development and progression

21 January 2018

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IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf.

21 January 2018

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IKKalpha provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development

21 January 2018

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IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis

21 January 2018

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IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

21 January 2018

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IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

21 January 2018

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Estrogen and antiestrogen regulation of cell cycle progression in breast cancer cells

21 January 2018

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HES-1 inhibits 17beta-estradiol and heregulin-beta1-mediated upregulation of E2F-1.

21 January 2018

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Transcriptional activation of E2F1 gene expression by 17beta-estradiol in MCF-7 cells is regulated by NF-Y-Sp1/estrogen receptor interactions

21 January 2018

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I-kappa B kinases alpha and beta have distinct roles in regulating murine T cell function

21 January 2018

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Analysis of domains in the IKKalpha and IKKbeta proteins that regulate their kinase activity

21 January 2018

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TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

21 January 2018

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ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance

21 January 2018

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TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival

21 January 2018

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Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression

21 January 2018

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A role for a bent DNA structure in E2F-mediated transcription activation

21 January 2018

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Cell Context-Dependent Differences in the Induction of E2F-1 Gene Expression by 17β-Estradiol in MCF-7 and ZR-75 Cells

21 January 2018

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Anatomy of the estrogen response element

21 January 2018

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IkappaB kinases: key regulators of the NF-kappaB pathway

21 January 2018

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IkappaB kinase alpha regulates subcellular distribution and turnover of cyclin D1 by phosphorylation

21 January 2018

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IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M512439200

1 reference

19 September 2017

1 reference