A region in urokinase plasminogen receptor domain III controlling a functional association with alpha5beta1 integrin and tumor growth (Q40302526)

19 September 2017

title

A region in urokinase plasminogen receptor domain III controlling a functional association with alpha5beta1 integrin and tumor growth (English)

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19 September 2017

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19 September 2017

Pratima Chaurasia

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19 September 2017

Julio A Aguirre-Ghiso

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19 September 2017

Olin D Liang

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19 September 2017

Henrik Gardsvoll

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19 September 2017

Liliana Ossowski

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19 September 2017

language of work or name

English

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publication date

17 March 2006

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Journal of Biological Chemistry

19 September 2017

published in

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19 September 2017

volume

281

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19 September 2017

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19 September 2017

page(s)

14852-14863

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Urokinase receptor and fibronectin regulate the ERK(MAPK) to p38(MAPK) activity ratios that determine carcinoma cell proliferation or dormancy in vivo.

19 September 2017

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Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling

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EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma

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Reduction in surface urokinase receptor forces malignant cells into a protracted state of dormancy

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uPAR: a versatile signalling orchestrator

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Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth.

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Plasminogen activators, integrins, and the coordinated regulation of cell adhesion and migration

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The urokinase receptor (uPAR) and the uPAR-associated protein (uPARAP/Endo180): membrane proteins engaged in matrix turnover during tissue remodeling

21 January 2018

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The very low density lipoprotein receptor regulates urokinase receptor catabolism and breast cancer cell motility in vitro

21 January 2018

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Urokinase-induced signaling in human vascular smooth muscle cells is mediated by PDGFR-beta

21 January 2018

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Regulation of integrin function by the urokinase receptor

21 January 2018

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Convergence of the adhesive and fibrinolytic systems: recognition of urokinase by integrin alpha Mbeta 2 as well as by the urokinase receptor regulates cell adhesion and migration

21 January 2018

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Crystal structure of the extracellular segment of integrin alpha Vbeta3

21 January 2018

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Distinct ligand binding sites in integrin α3β1 regulate matrix adhesion and cell–cell contact

21 January 2018

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Regulation of alpha5beta1 integrin conformation and function by urokinase receptor binding.

21 January 2018

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Identification of a urokinase receptor-integrin interaction site. Promiscuous regulator of integrin function

21 January 2018

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Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide

21 January 2018

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Structure of human urokinase plasminogen activator in complex with its receptor

21 January 2018

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The urokinase-type plasminogen activator system in cancer metastasis: A review

21 January 2018

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The urokinase plasminogen activator system in cancer: recent advances and implication for prognosis and therapy.

21 January 2018

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Cell-induced potentiation of the plasminogen activation system is abolished by a monoclonal antibody that recognizes the NH2-terminal domain of the urokinase receptor

21 January 2018

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Intermolecular contact regions in urokinase plasminogen activator receptor

21 January 2018

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Mapping part of the functional epitope for ligand binding on the receptor for urokinase-type plasminogen activator by site-directed mutagenesis

21 January 2018

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Characterization of low-glycosylated forms of soluble human urokinase receptor expressed in Drosophila Schneider 2 cells after deletion of glycosylation-sites.

21 January 2018

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Glycosylation profile of a recombinant urokinase-type plasminogen activator receptor expressed in Chinese hamster ovary cells

21 January 2018

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Structural analysis and tissue localization of human C4.4A: a protein homologue of the urokinase receptor

21 January 2018

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Activated conformations of very late activation integrins detected by a group of antibodies (HUTS) specific for a novel regulatory region (355-425) of the common beta 1 chain

21 January 2018

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Urokinase receptors promote beta1 integrin function through interactions with integrin alpha3beta1.

21 January 2018

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Dynamic assembly of the urokinase-type plasminogen activator signaling receptor complex determines the mitogenic activity of urokinase-type plasminogen activator.

21 January 2018

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Urokinase receptor and integrin interactions

21 January 2018

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Three-dimensional EM structure of the ectodomain of integrin {alpha}V{beta}3 in a complex with fibronectin

21 January 2018

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Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction.

21 January 2018

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Regulation of integrin function through conformational complexity: not simply a knee-jerk reaction?

21 January 2018

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Disruption of the beta3 663-687 disulfide bridge confers constitutive activity to beta3 integrins

21 January 2018

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Agonist-specific structural rearrangements of integrin alpha IIbbeta 3. Confirmation of the bent conformation in platelets at rest and after activation

21 January 2018

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Domain 2 of the urokinase receptor contains an integrin-interacting epitope with intrinsic signaling activity: generation of a new integrin inhibitor

21 January 2018

1 reference

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Conformational Changes in the Integrin βA Domain Provide a Mechanism for Signal Transduction via Hybrid Domain Movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M512311200

21 January 2018

Identifiers

DOI

10.1074/JBC.M512311200

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19 September 2017

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