Modelling the regulation of thermal adaptation in Candida albicans, a major fungal pathogen of humans (Q40292403)

19 September 2017

Modelling the regulation of thermal adaptation in Candida albicans, a major fungal pathogen of humans (English)

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19 September 2017

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19 September 2017

Edda Klipp

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author name string

Michelle D Leach

series ordinal

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19 September 2017

Katarzyna M Tyc

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19 September 2017

language of work or name

English

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publication date

20 March 2012

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19 September 2017

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19 September 2017

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19 September 2017

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19 September 2017

e32467

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Creative Commons Attribution 4.0 International

19 September 2017

start time

20 March 2012

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April 2022 Public Data File from Crossref

copyrighted

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cites work

Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicans

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Model-based inference of biochemical parameters and dynamic properties of microbial signal transduction networks

22 September 2017

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Activation of the heat shock transcription factor Hsf1 is essential for the full virulence of the fungal pathogen Candida albicans

22 September 2017

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Annotation and merging of SBML models with semanticSBML

22 September 2017

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COPASI--a COmplex PAthway SImulator

22 September 2017

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Module-based analysis of robustness tradeoffs in the heat shock response system

22 September 2017

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Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shock

22 September 2017

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Fungal heat-shock proteins in human disease

22 September 2017

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Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi

22 September 2017

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Heat shock response modulators as therapeutic tools for diseases of protein conformation

22 September 2017

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Mathematical modeling of the eukaryotic heat-shock response: dynamics of the hsp70 promoter.

22 September 2017

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On mechanisms that control heat shock transcription factor activity in metazoan cells

22 September 2017

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Pathways of chaperone-mediated protein folding in the cytosol

22 September 2017

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A conserved stress-activated protein kinase regulates a core stress response in the human pathogen Candida albicans

22 September 2017

1 reference

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Protein degradation and protection against misfolded or damaged proteins

22 September 2017

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Epidemiology of Candida species infections in critically ill non-immunosuppressed patients

22 September 2017

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Global analysis of protein expression in yeast

22 September 2017

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Engineered control of cell morphology in vivo reveals distinct roles for yeast and filamentous forms of Candida albicans during infection

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Preclinical assessment of the efficacy of mycograb, a human recombinant antibody against fungal HSP90

22 September 2017

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Stress-induced gene expression in Candida albicans: absence of a general stress response.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Sequential fractionation and two-dimensional gel analysis unravels the complexity of the dimorphic fungus Candida albicans cell wall proteome

22 September 2017

1 reference

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Fungal morphogenesis and host invasion

22 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex

22 September 2017

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Tetracycline-regulatable system to tightly control gene expression in the pathogenic fungus Candida albicans

22 September 2017

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Robust perfect adaptation in bacterial chemotaxis through integral feedback control

22 September 2017

1 reference

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The yeast Hsp110 family member, Sse1, is an Hsp90 cochaperone

22 September 2017

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On the path to the heat shock response: destabilization and formation of partially folded protein intermediates, a consequence of protein thiol modification

22 September 2017

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Heat-shock protein protection.

22 September 2017

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Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

HSP90 interacts with and regulates the activity of heat shock factor 1 in Xenopus oocytes

22 September 2017

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Correlation between glutathione oxidation and trimerization of heat shock factor 1, an early step in stress induction of the Hsp response

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Requirement for Hsp90 and a CyP-40-type cyclophilin in negative regulation of the heat shock response

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

A 70-kilodalton recombinant heat shock protein of Candida albicans is highly immunogenic and enhances systemic murine candidiasis.

22 September 2017

1 reference

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Nonfilamentous C. albicans Mutants Are Avirulent

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Evidence for a role of Hsp 70 in the regulation of the heat shock response in mammalian cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

A model of excitation and adaptation in bacterial chemotaxis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Robustness in simple biochemical networks

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

The highly immunogenic enolase and Hsp70p are adventitious Candida albicans cell wall proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Heat shock transcription factors: structure and regulation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Cells in stress: transcriptional activation of heat shock genes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Protein denaturation in intact hepatocytes and isolated cellular organelles during heat shock

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

The DNA-binding activity of the human heat shock transcription factor is regulated in vivo by hsp70.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Interaction between heat shock factor and hsp70 is insufficient to suppress induction of DNA-binding activity in vivo

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Structure and regulation of the HSP90 gene from the pathogenic fungus Candida albicans

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Quantitative analysis of the heat shock response of Saccharomyces cerevisiae.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Genetic control of heat-shock protein synthesis and its bearing on growth and thermal resistance in Escherichia coli K-12

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Correlation between synthesis of heat shock proteins and development of thermotolerance in Chinese hamster fibroblasts

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Recovery of protein synthesis after heat shock: prior heat treatment affects the ability of cells to translate mRNA

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Ecology and epidemiology of Candida species.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

A synthetic heat-shock promoter element confers heat-inducibility on the herpes simplex virus thymidine kinase gene

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

A molecular mechanism for sensory adaptation based on ligand-induced receptor modification

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

22 September 2017

The heat-shock response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Heat shock factor and the heat shock response

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Getting started with yeast

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Heat shock gene regulation by nascent polypeptides and denatured proteins: hsp70 as a potential autoregulatory factor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

The role of heat-shock proteins in thermotolerance

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Identification of sumoylation targets, combined with inactivation of SMT3, reveals the impact of sumoylation upon growth, morphology, and stress resistance in the pathogen Candida albicans.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Adaptive tolerance to oxidative stress and the induction of antioxidant enzymatic activities in Candida albicans are independent of the Hog1 and Cap1-mediated pathways

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Role of the heat shock transcription factor, Hsf1, in a major fungal pathogen that is obligately associated with warm-blooded animals.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Transcriptional profiling on all open reading frames of Saccharomyces cerevisiae.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Heat-inducible ATP-binding proteins of Candida albicans are recognized by sera of infected patients

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Abnormal proteins serve as eukaryotic stress signals and trigger the activation of heat shock genes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

A systems-level analysis of perfect adaptation in yeast osmoregulation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Attributable mortality of nosocomial candidemia, revisited

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Sensitivity analysis of stoichiometric networks: an extension of metabolic control analysis to non-steady state trajectories.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Short circuiting stress protein expression via a tyrosine kinase inhibitor, herbimycin A.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Varying patterns of protein synthesis in Drosophila during heat shock: implications for regulation.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Heat shock response of Dictyostelium.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

A Drosophila RNA polymerase II transcription factor binds to the regulatory site of an hsp 70 gene

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308945

Heat shock proteins and thermal resistance in yeast

20 August 2018

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12 December 2020

Positive regulatory gene for temperature-controlled proteins in Escherichia coli

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12 December 2020

Induced thermal tolerance and heat shock protein synthesis in Chinese hamster ovary cells

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12 December 2020

Hospital-acquired candidemia. The attributable mortality and excess length of stay

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12 December 2020

Autoantibody to heat-shock protein 90 can mediate protection against systemic candidosis

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12 December 2020

Thermotolerance and trehalose accumulation induced by heat shock in yeast cells of Candida albicans

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0032467

Identifiers

DOI

1 reference

19 September 2017

0 references

1 reference

19 September 2017

PubMed publication ID

22448221

1 reference