Common chromatin structures at breakpoint cluster regions may lead to chromosomal translocations found in chronic and acute leukemias (Q40298309)

19 September 2017

title

Common chromatin structures at breakpoint cluster regions may lead to chromosomal translocations found in chronic and acute leukemias (English)

1 reference

19 September 2017

Reiner Strick

1 reference

19 September 2017

Yanming Zhang

series ordinal

1 reference

19 September 2017

Neelmini Emmanuel

series ordinal

1 reference

19 September 2017

Pamela L Strissel

series ordinal

1 reference

19 September 2017

language of work or name

1 reference

30 March 2006

1 reference

19 September 2017

1 reference

19 September 2017

volume

119

1 reference

19 September 2017

1 reference

19 September 2017

page(s)

479-495

1 reference

11q23 balanced chromosome aberrations in treatment-related myelodysplastic syndromes and acute leukemia: report from an international workshop

19 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00439-006-0146-9

Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-006-0146-9

DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-006-0146-9

Chromatin structure, not DNA sequence specificity, is the primary determinant of topoisomerase II sites of action in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-006-0146-9

Structure and function of type II DNA topoisomerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-006-0146-9

Spontaneous DNA lesions poison human topoisomerase IIalpha and stimulate cleavage proximal to leukemic 11q23 chromosomal breakpoints

21 January 2018

1 reference

12 December 2020

In vivo mapping of DNA topoisomerase II-specific cleavage sites on SV40 chromatin.

1 reference

12 December 2020

Effect of the DNA topoisomerase II inhibitor VP-16 on illegitimate recombination in yeast chromosomes

1 reference

12 December 2020

Periodicity of DNA folding in higher order chromatin structures

1 reference

12 December 2020

Meiosis-induced double-strand break sites determined by yeast chromatin structure

1 reference

12 December 2020

DNA topoisomerase IIalpha interacts with CAD nuclease and is involved in chromatin condensation during apoptotic execution

1 reference

12 December 2020

Infant leukaemia biology, aetiology and treatment

1 reference

12 December 2020

Breakpoints of t(4;11) translocations in the human MLL and AF4 genes in ALL patients are preferentially clustered outside of high-affinity matrix attachment regions

1 reference

12 December 2020

Sequence and Analysis of the Human ABL Gene, the BCR Gene, and Regions Involved in the Philadelphia Chromosomal Translocation

1 reference

12 December 2020

DNA topoisomerase poisons as antitumor drugs

1 reference

12 December 2020

ALL-1 partial duplication in acute leukemia

1 reference

12 December 2020

Structural characterization of the BCR gene product

1 reference

12 December 2020

Chromatin alterations surrounding the BCR/ABL fusion gene in K562 cells

1 reference

12 December 2020

Biased distribution of chromosomal breakpoints involving the MLL gene in infants versus children and adults with t(4;11) ALL.

1 reference

12 December 2020

Cation-chromatin binding as shown by ion microscopy is essential for the structural integrity of chromosomes

1 reference

12 December 2020

International workshop on the relationship of prior therapy to balanced chromosome aberrations in therapy-related myelodysplastic syndromes and acute leukemia: overview report

1 reference

12 December 2020

Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia

1 reference

12 December 2020

Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X alpha-satellite array

1 reference

12 December 2020

Nonrandom distribution of interspersed repeat elements in the BCR and ABL1 genes and its relation to breakpoint cluster regions

1 reference

12 December 2020

Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: almost identical MLL breakpoints in therapy-related AML after treatment without etoposides

1 reference

12 December 2020

Illegitimate recombination mediated by calf thymus DNA topoisomerase II in vitro

1 reference

12 December 2020

Structural analysis of mouse rDNA: coincidence between nuclease hypersensitive sites, DNA curvature and regulatory elements in the intergenic spacer

1 reference

12 December 2020

Rapid isolation of chromosomal breakpoints from patients with t(4;11) acute lymphoblastic leukemia: implications for basic and clinical research.

1 reference

12 December 2020

Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation

1 reference

12 December 2020

Degradation of eukaryotic polypeptide chain initiation factor (eIF) 4G in response to induction of apoptosis in human lymphoma cell lines

1 reference

12 December 2020

Breakpoint cluster regions of the AML-1 and ETO genes contain MAR elements and are preferentially associated with the nuclear matrix in proliferating HEL cells

1 reference

12 December 2020

A consensus sequence for cleavage by vertebrate DNA topoisomerase II.

1 reference

12 December 2020

Dysfunction of chromosomal loop attachment sites: illegitimate recombination linked to matrix association regions and topoisomerase II.

1 reference

12 December 2020

SARs are cis DNA elements of chromosome dynamics: synthesis of a SAR repressor protein.

1 reference

12 December 2020

Fatal connections: when DNA ends meet on the nuclear matrix.

1 reference

12 December 2020

The BCR gene recombines preferentially with Alu elements in complex BCR-ABL translocations of chronic myeloid leukaemia

1 reference

12 December 2020

DNA structural properties of AF9 are similar to MLL and could act as recombination hot spots resulting in MLL/AF9 translocations and leukemogenesis

1 reference

12 December 2020

AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23)

1 reference

12 December 2020

Double-strand breaks and translocations in cancer

1 reference

12 December 2020

Site-specific DNA cleavage within the MLL breakpoint cluster region induced by topoisomerase II inhibitors.

1 reference

12 December 2020

Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs

1 reference

12 December 2020

The t(4;22)(q12;q11) in atypical chronic myeloid leukaemia fuses BCR to PDGFRA.

1 reference

12 December 2020

The role of topoisomerase II in the excision of DNA loop domains during apoptosis

1 reference

12 December 2020

Translocation and gross deletion breakpoints in human inherited disease and cancer I: Nucleotide composition and recombination-associated motifs

1 reference

12 December 2020

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

1 reference

12 December 2020

Fine structure of translocation breakpoints in leukemic blasts with chromosomal translocation t(4;11): the DNA damage-repair model of translocation

1 reference

12 December 2020

MLL2: A new mammalian member of the trx/MLL family of genes

1 reference

12 December 2020

Bcr-Abl variants: biological and clinical aspects

1 reference

12 December 2020

Analysis of the region of the 5' end of the MLL gene involved in genomic duplication events.

1 reference

12 December 2020

Large deletions at the t(9;22) breakpoint are common and may identify a poor-prognosis subgroup of patients with chronic myeloid leukemia

1 reference

12 December 2020

MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines

1 reference

12 December 2020

The novel activation of ABL by fusion to an ets-related gene, TEL.

1 reference

12 December 2020

Drug-specific sites of topoisomerase II DNA cleavage in Drosophila chromatin: heterogeneous localization and reversibility.

1 reference

12 December 2020

Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites

1 reference

12 December 2020

DNA topoisomerase IIalpha is required for RNA polymerase II transcription on chromatin templates

1 reference

12 December 2020

DNA double strand breaks (DSB) and non-homologous end joining (NHEJ) pathways in human leukemia

1 reference

12 December 2020

1 reference

12 December 2020

Scaffold attachment regions in centromere-associated DNA

1 reference

12 December 2020

Rapid and sensitive detection of all types of MLL gene translocations with a single FISH probe set.

1 reference

12 December 2020

Potential topoisomerase II DNA-binding sites at the breakpoints of a t(9;11) chromosome translocation in acute myeloid leukemia

1 reference

12 December 2020

Polymorphisms in the MLL breakpoint cluster region (BCR)

1 reference

12 December 2020

An in vivo topoisomerase II cleavage site and a DNase I hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region

1 reference

12 December 2020

Scaffold-associated regions in the human type I interferon gene cluster on the short arm of chromosome 9.

1 reference

12 December 2020

The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins

1 reference

12 December 2020

Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells

1 reference

12 December 2020

1 reference

12 December 2020

Apoptotic triggers initiate translocations within the MLL gene involving the nonhomologous end joining repair system

1 reference

12 December 2020

Chromosomal breakpoints within the first intron of the ABL gene are nonrandom in patients with chronic myelogenous leukemia

1 reference

12 December 2020

A novel selection system for chromosome translocations in Saccharomyces cerevisiae.

1 reference

12 December 2020

A 76-kb duplicon maps close to the BCR gene on chromosome 22 and the ABL gene on chromosome 9: possible involvement in the genesis of the Philadelphia chromosome translocation

1 reference

12 December 2020

Characterization of genomic breakpoints in MLL and CBP in leukemia patients with t(11;16).

1 reference

12 December 2020

Dietary flavonoids and the MLL gene: A pathway to infant leukemia?

1 reference

12 December 2020

Etoposide induces chimeric Mll gene fusions

1 reference

12 December 2020

Etoposide targets topoisomerase IIalpha and IIbeta in leukemic cells: isoform-specific cleavable complexes visualized and quantified in situ by a novel immunofluorescence technique

1 reference

12 December 2020

Specific histone patterns and acetylase/deacetylase activity at the breakpoint-cluster region of the human MLL gene

1 reference

12 December 2020

Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia.

1 reference

12 December 2020

The role of chromosome translocations in leukemogenesis.

1 reference

12 December 2020

Chromosome recombination and defective genome segregation induced in Chinese hamster cells by the topoisomerase II inhibitor VM-26

1 reference

12 December 2020

Etoposide and antimetabolite pharmacology in patients who develop secondary acute myeloid leukemia

1 reference

12 December 2020

Molecular analysis of 13 cases of MLL/11q23 secondary acute leukemia and identification of topoisomerase II consensus-binding sequences near the chromosomal breakpoint of a secondary leukemia with the t(4;11).

1 reference

12 December 2020

10.1007/S00439-006-0146-9

Identifiers

DOI

1 reference

Dimensions Publication ID

19 September 2017

1024394684

0 references

1 reference