The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation. (Q40252205)

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scientific article published on 24 July 2006

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English	The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation.	scientific article published on 24 July 2006

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27 December 2019

The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation (English)

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27 December 2019

Renske D. Steenbergen

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Anthony Tak-Cheung Chan

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27 December 2019

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Seng TJ

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Low JS

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Li H

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Cui Y

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Goh HK

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Wong ML

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27 December 2019

Srivastava G

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27 December 2019

Sidransky D

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27 December 2019

Califano J

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27 December 2019

Tan J

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27 December 2019

Hsieh WS

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Ambinder RF

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Lin X

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24 July 2006

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27 December 2019

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The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma.

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DLC-1 gene inhibits human breast cancer cell growth and in vivo tumorigenicity

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Frequent hypermethylation of RASSF1A and TSLC1, and high viral load of Epstein-Barr Virus DNA in nasopharyngeal carcinoma and matched tumor-adjacent tissues.

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10.1038/SJ.ONC.1209839

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27 December 2019

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