Mucosal HIV-1 pox virus prime-boost immunization induces high-avidity CD8+ T cells with regime-dependent cytokine/granzyme B profiles (Q40245279)

18 September 2017

title

Mucosal HIV-1 pox virus prime-boost immunization induces high-avidity CD8+ T cells with regime-dependent cytokine/granzyme B profiles (English)

1 reference

18 September 2017

Stephen J Turner

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Peter C Doherty

1 reference

18 September 2017

Charani Ranasinghe

1 reference

18 September 2017

Craig McArthur

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18 September 2017

Duncan B Sutherland

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18 September 2017

Jee-Hye Kim

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18 September 2017

Ian A Ramshaw

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18 September 2017

language of work or name

English

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publication date

1 February 2007

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18 September 2017

published in

Journal of Immunology

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18 September 2017

volume

178

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18 September 2017

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18 September 2017

page(s)

2370-2379

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Fowlpox virus vaccines for HIV and SHIV clinical and pre-clinical trials

18 September 2017

cites work

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.4049/JIMMUNOL.178.4.2370

Evaluation of fowlpox-vaccinia virus prime-boost vaccine strategies for high-level mucosal and systemic immunity against HIV-1.

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A Phase II Study of Two HIV Type 1 Envelope Vaccines, Comparing Their Immunogenicity in Populations at Risk for Acquiring HIV Type 1 Infection

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A single peripheral CD8+T cell can give rise to progeny expressing type 1 and/or type 2 cytokine genes and can retain its multipotentiality through many cell divisions

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A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials: stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans

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Contribution of T cell receptor affinity to overall avidity for virus-specific CD8+ T cell responses

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12 October 2022

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High-avidity CTL exploit two complementary mechanisms to provide better protection against viral infection than low-avidity CTL.

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Optimal kinetics for quantification of antigen-induced cytokines in human peripheral blood mononuclear cells by real-time PCR and by ELISA.

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High-avidity CD8+ T cells: optimal soldiers in the war against viruses and tumors

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Expression of secreted cytokine and chemokine inhibitors by ectromelia virus

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IL-2 regulates perforin and granzyme gene expression in CD8+ T cells independently of its effects on survival and proliferation

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Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region

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Analysis of clonotype distribution and persistence for an influenza virus-specific CD8+ T cell response

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NALT- versus Peyer's-patch-mediated mucosal immunity

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4-1BBL coexpression enhances HIV-specific CD8 T cell memory in a poxvirus prime-boost vaccine

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A clonal culture system demonstrates that IL-4 induces a subpopulation of noncytolytic T cells with low CD8, perforin, and granzyme expression

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Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL

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HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

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Vaccinia virus induces strong immunoregulatory cytokine production in healthy human epidermal keratinocytes: a novel strategy for immune evasion

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Mucosally-administered human-simian immunodeficiency virus DNA and fowlpoxvirus-based recombinant vaccines reduce acute phase viral replication in macaques following vaginal challenge with CCR5-tropic SHIVSF162P3.

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Enhanced CD8+ T cell immune responses and protection elicited against Plasmodium berghei malaria by prime boost immunization regimens using a novel attenuated fowlpox virus

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Antigen density presented by dendritic cells in vivo differentially affects the number and avidity of primary, memory, and recall CD8+ T cells.

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Flow cytometric determination of cytokine production and proliferation in hepatitis B core antigen specific murine CD4 cells: lack of correlation between number of cytokine producing cells and cytokine levels in supernatant

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Expression of mouse interleukin-4 by a recombinant ectromelia virus suppresses cytolytic lymphocyte responses and overcomes genetic resistance to mousepox.

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Identifiers

DOI

10.4049/JIMMUNOL.178.4.2370

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release_ldqlwdo4cndrhaawa2wjgb7jv4

18 September 2017

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