Toll-like receptor 4 region Glu24-Lys47 is a site for MD-2 binding: importance of CYS29 and CYS40. (Q40216944)

18 September 2017

title

Toll-like receptor 4 region Glu24-Lys47 is a site for MD-2 binding: importance of CYS29 and CYS40. (English)

1 reference

18 September 2017

0 references

Chiaki Nishitani

1 reference

18 September 2017

Hiroaki Mitsuzawa

1 reference

18 September 2017

Hitomi Sano

1 reference

18 September 2017

Takeyuki Shimizu

1 reference

18 September 2017

Norio Matsushima

1 reference

18 September 2017

Yoshio Kuroki

1 reference

18 September 2017

language of work or name

English

0 references

publication date

20 October 2006

1 reference

Journal of Biological Chemistry

18 September 2017

published in

1 reference

18 September 2017

volume

281

1 reference

18 September 2017

1 reference

18 September 2017

page(s)

38322-38329

1 reference

Phylogenetic perspectives in innate immunity

18 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

Toll-like receptors in the induction of the innate immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

Structure and function of lipopolysaccharide binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

The amino-terminal region of toll-like receptor 4 is essential for binding to MD-2 and receptor translocation to the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

The Toll-like receptor 4 region Glu24-Pro34 is critical for interaction with MD-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

Interaction of soluble form of recombinant extracellular TLR4 domain with MD-2 enables lipopolysaccharide binding and attenuates TLR4-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

The extracellular toll-like receptor 2 domain directly binds peptidoglycan derived from Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

Extracellular Toll-like receptor 2 region containing Ser40-Ile64 but not Cys30-Ser39 is critical for the recognition of Staphylococcus aureus peptidoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

Soluble MD-2 activity in plasma from patients with severe sepsis and septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

Crystal structure of the platelet glycoprotein Ib(alpha) N-terminal domain reveals an unmasking mechanism for receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

The molecular structure of the Toll-like receptor 3 ligand-binding domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

Mapping the protein universe

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

Crystal structure of human toll-like receptor 3 (TLR3) ectodomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M606904200

21 January 2018

Identifiers

DOI

10.1074/JBC.M606904200

1 reference

18 September 2017

1 reference