Hepatitis C virus NS5A is a direct substrate of casein kinase I-alpha, a cellular kinase identified by inhibitor affinity chromatography using specific NS5A hyperphosphorylation inhibitors (Q40196972)

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scientific article published on 13 December 2006

Language	Label	Description	Also known as
English	Hepatitis C virus NS5A is a direct substrate of casein kinase I-alpha, a cellular kinase identified by inhibitor affinity chromatography using specific NS5A hyperphosphorylation inhibitors	scientific article published on 13 December 2006

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scholarly article

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Europe PubMed Central

PubMed publication ID

18 September 2017

Hepatitis C virus NS5A is a direct substrate of casein kinase I-alpha, a cellular kinase identified by inhibitor affinity chromatography using specific NS5A hyperphosphorylation inhibitors (English)

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Europe PubMed Central

PubMed publication ID

18 September 2017

Hepatitis C virus

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Raffaele De Francesco

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Raffaele De Francesco

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author name string

Manuela Quintavalle

1

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Europe PubMed Central

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18 September 2017

Sonia Sambucini

2

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Europe PubMed Central

PubMed publication ID

18 September 2017

Vincenzo Summa

3

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Europe PubMed Central

PubMed publication ID

18 September 2017

Laura Orsatti

4

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Europe PubMed Central

PubMed publication ID

18 September 2017

Fabio Talamo

5

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18 September 2017

Petra Neddermann

7

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18 September 2017

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publication date

13 December 2006

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18 September 2017

Journal of Biological Chemistry

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18 September 2017

282

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PubMed publication ID

18 September 2017

8

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18 September 2017

5536-5544

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18 September 2017

Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Identification of the Hepatitis C Virus RNA Replication Complex in Huh-7 Cells Harboring Subgenomic Replicons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

From structure to function: new insights into hepatitis C virus RNA replication

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Efficient rescue of hepatitis C virus RNA replication by trans-complementation with nonstructural protein 5A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Trans-complementation of HCV replication by non-structural protein 5A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Hepatitis C virus NS5A: tales of a promiscuous protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Effect of interaction between hepatitis C virus NS5A and NS5B on hepatitis C virus RNA replication with the hepatitis C virus replicon

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

The NS5A protein of the hepatitis C virus genotype 1a is cleaved by caspases to produce C-terminal-truncated forms of the protein that reside mainly in the cytosol

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Production of two phosphoproteins from the NS5A region of the hepatitis C viral genome.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Dominant negative effect of wild-type NS5A on NS5A-adapted subgenomic hepatitis C virus RNA replicon

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

The NS5A protein of hepatitis C virus is a zinc metalloprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Efficient initiation of HCV RNA replication in cell culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Reduction of hepatitis C virus NS5A hyperphosphorylation by selective inhibition of cellular kinases activates viral RNA replication in cell culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Viral and Cellular Determinants of Hepatitis C Virus RNA Replication in Cell Culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

The Isoform of Protein Kinase CKI Is Responsible for Hepatitis C Virus NS5A Hyperphosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Purification and characterization of hepatitis C virus non-structural protein 5A expressed in Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

In Vitro Selection and Characterization of Hepatitis C Virus Serine Protease Variants Resistant to an Active-Site Peptide Inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Ser(2194) is a highly conserved major phosphorylation site of the hepatitis C virus nonstructural protein NS5A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

An efficient proteomics method to identify the cellular targets of protein kinase inhibitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Hepatitis C virus NS5A protein is phosphorylated by casein kinase II.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Hepatitis C virus NS5A protein is phosphorylated in vitro by a stably bound protein kinase from HeLa cells and by cAMP-dependent protein kinase A-α catalytic subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

High-throughput screening of the yeast kinome: identification of human serine/threonine protein kinases that phosphorylate the hepatitis C virus NS5A protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Chemical proteomic analysis reveals alternative modes of action for pyrido[2,3-d]pyrimidine kinase inhibitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

A phosphatidylinositol 4,5-bisphosphate-sensitive casein kinase I alpha associates with synaptic vesicles and phosphorylates a subset of vesicle proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610486200

21 January 2018

Identifiers

10.1074/JBC.M610486200

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

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