A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK pathways. (Q40181009)

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24 December 2019

title

A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK pathways (English)

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24 December 2019

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24 December 2019

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24 December 2019

Kim D

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24 December 2019

Cho KH

series ordinal

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24 December 2019

language of work or name

English

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publication date

22 January 2007

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24 December 2019

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24 December 2019

volume

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24 December 2019

issue

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24 December 2019

page(s)

4571-4579

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β-catenin is a target for the ubiquitin–proteasome pathway

24 December 2019

cites work

1 reference

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7 January 2021

Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT.

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Mutations of the BRAF gene in ulcerative colitis-related colorectal carcinoma

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The role of the Wnt signalling pathway in colorectal tumorigenesis

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7 January 2021

The Wnt connection to tumorigenesis

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7 January 2021

Okadaic acid activates p42 mitogen-activated protein kinase (MAP kinase; ERK-2) in B-lymphocytes but inhibits rather than augments cellular proliferation: contrast with phorbol 12-myristate 13-acetate

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7 January 2021

Wnt pathway mutations selected by optimal beta-catenin signaling for tumorigenesis

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7 January 2021

Mathematical Modeling of the Influence of RKIP on the ERK Signaling Pathway

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7 January 2021

Wnt1 and Wnt5a induce cyclin D1 expression through ErbB1 transactivation in HC11 mammary epithelial cells.

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7 January 2021

Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.

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7 January 2021

Targeting RAS signalling pathways in cancer therapy

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7 January 2021

Cross-talk between Rac1 GTPase and dysregulated Wnt signaling pathway leads to cellular redistribution of beta-catenin and TCF/LEF-mediated transcriptional activation

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7 January 2021

The MAPK signalling pathways and colorectal cancer

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7 January 2021

Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability

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7 January 2021

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

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7 January 2021

Pin1 overexpression in colorectal cancer and its correlation with aberrant beta-catenin expression

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7 January 2021

Overexpression of beta-catenin induces apoptosis independent of its transactivation function with LEF-1 or the involvement of major G1 cell cycle regulators

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7 January 2021

Lessons from hereditary colorectal cancer

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7 January 2021

Coordinating ERK/MAPK signalling through scaffolds and inhibitors

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7 January 2021

When kinases meet mathematics: the systems biology of MAPK signalling

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7 January 2021

The role of Raf kinases in malignant transformation.

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7 January 2021

The Roles of APC and Axin Derived from Experimental and Theoretical Analysis of the Wnt Pathway

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7 January 2021

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

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7 January 2021

Extensive DNA methylation in normal colorectal mucosa in hyperplastic polyposis.

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7 January 2021

Wnt signalling in stem cells and cancer

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7 January 2021

A Raf/MEK/ERK signaling pathway is required for development of the sea urchin embryo micromere lineage through phosphorylation of the transcription factor Ets.

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7 January 2021

Live and let die in the intestinal epithelium

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7 January 2021

Signaling pathways in intestinal development and cancer

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7 January 2021

Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers

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7 January 2021

A systems- and signal-oriented approach to intracellular dynamics

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7 January 2021

Small changes in expression affect predisposition to tumorigenesis

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7 January 2021

Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP

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7 January 2021

Both ERK and Wnt/beta-catenin pathways are involved in Wnt3a-induced proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210230

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210230

1 reference

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Dimensions Publication ID

24 December 2019

1003830733

0 references

1 reference

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