MBNL binds similar RNA structures in the CUG repeats of myotonic dystrophy and its pre-mRNA substrate cardiac troponin T. (Q40189215)

18 September 2017

MBNL binds similar RNA structures in the CUG repeats of myotonic dystrophy and its pre-mRNA substrate cardiac troponin T. (English)

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18 September 2017

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M Bryan Warf

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18 September 2017

J Andrew Berglund

series ordinal

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18 September 2017

language of work or name

English

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publication date

17 October 2007

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18 September 2017

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18 September 2017

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18 September 2017

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18 September 2017

2238-2251

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describes a project that uses

18 September 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2080590/fullTextXML

inferred from PubMed Central ID database lookup

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Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing

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Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy

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RNA-dependent integrin alpha3 protein localization regulated by the Muscleblind-like protein MLP1

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The structural basis of myotonic dystrophy from the crystal structure of CUG repeats

22 September 2017

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Colocalization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in myotonic dystrophy

22 September 2017

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Transgenic mice expressing CUG-BP1 reproduce splicing mis-regulation observed in myotonic dystrophy.

22 September 2017

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Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development

22 September 2017

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MBNL1 is the primary determinant of focus formation and aberrant insulin receptor splicing in DM1

22 September 2017

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22 September 2017

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Toxic RNA in the nucleus: unstable microsatellite expression in neuromuscular disease.

22 September 2017

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22 September 2017

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Muscleblind protein, MBNL1/EXP, binds specifically to CHHG repeats

22 September 2017

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A muscleblind knockout model for myotonic dystrophy

22 September 2017

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RNA structure of trinucleotide repeats associated with human neurological diseases

22 September 2017

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Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3

22 September 2017

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Formation of stable triplexes between purine RNA and pyrimidine oligodeoxyxylonucleotides

22 September 2017

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22 September 2017

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Molecular cloning, developmental expression, promoter analysis and functional characterization of the mouse CNBP gene

22 September 2017

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Inhibition of muscle differentiation by the novel muscleblind-related protein CHCR

22 September 2017

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Loss of the muscle-specific chloride channel in type 1 myotonic dystrophy due to misregulated alternative splicing

22 September 2017

1 reference

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Three proteins, MBNL, MBLL and MBXL, co-localize in vivo with nuclear foci of expanded-repeat transcripts in DM1 and DM2 cells.

22 September 2017

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Muscleblind localizes to nuclear foci of aberrant RNA in myotonic dystrophy types 1 and 2.

22 September 2017

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Molecular basis for impaired muscle differentiation in myotonic dystrophy

22 September 2017

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Myotonic dystrophy type 2 caused by a CCTG expansion in intron 1 of ZNF9

22 September 2017

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Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy

22 September 2017

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Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR

22 September 2017

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22 September 2017

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Visualization of double-stranded RNAs from the myotonic dystrophy protein kinase gene and interactions with CUG-binding protein

22 September 2017

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Evidence from CD spectra that d(purine).r(pyrimidine) and r(purine).d(pyrimidine) hybrids are in different structural classes

22 September 2017

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Use of ultra stable UNCG tetraloop hairpins to fold RNA structures: thermodynamic and spectroscopic applications

22 September 2017

1 reference

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A secondary structure at the 3' splice site affects the in vitro splicing reaction of mouse immunoglobulin mu chain pre-mRNAs

22 September 2017

1 reference

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Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2080590

An RNA map predicting Nova-dependent splicing regulation

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2080590

Hairpin structure-forming propensity of the (CCTG.CAGG) tetranucleotide repeats contributes to the genetic instability associated with myotonic dystrophy type 2.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2080590

Calculating sedimentation coefficient distributions by direct modeling of sedimentation velocity concentration profiles

20 August 2018

1 reference

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muscleblind, a gene required for photoreceptor differentiation in Drosophila, encodes novel nuclear Cys3His-type zinc-finger-containing proteins

20 August 2018

1 reference

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Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat

20 August 2018

1 reference

12 December 2020

Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy

1 reference

12 December 2020

Ribonuclear inclusions in skeletal muscle in myotonic dystrophy types 1 and 2

1 reference

12 December 2020

Tissue-specific splicing in vivo of the beta-tropomyosin gene: dependence on an RNA secondary structure

1 reference

12 December 2020

CUG Repeats Present in Myotonin Kinase RNA Form Metastable “Slippery” Hairpins

1 reference

12 December 2020

Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons

1 reference

12 December 2020

Identifiers

DOI

10.1261/RNA.610607

1 reference

18 September 2017

1 reference

18 September 2017

PubMed publication ID

17942744

1 reference