Pharmacologic activation of p53-dependent and p53-independent apoptotic pathways in Hodgkin/Reed-Sternberg cells (Q40176347)

18 September 2017

title

Pharmacologic activation of p53-dependent and p53-independent apoptotic pathways in Hodgkin/Reed-Sternberg cells (English)

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18 September 2017

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M Janz

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18 September 2017

T Stühmer

series ordinal

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18 September 2017

L T Vassilev

series ordinal

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18 September 2017

R C Bargou

series ordinal

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18 September 2017

publication date

1 February 2007

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18 September 2017

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18 September 2017

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18 September 2017

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18 September 2017

page(s)

772-779

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Nucleolar p14(ARF) overexpression in Reed-Sternberg cells in Hodgkin's lymphoma: absence of p14(ARF)/Hdm2 complexes is associated with expression of alternatively spliced Hdm2 transcripts

18 September 2017

cites work

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Secondary myeloid leukemia and myelodysplastic syndromes in patients treated for Hodgkin's disease: a report from the German Hodgkin's Lymphoma Study Group

21 January 2018

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7 January 2021

Second malignancy after treatment of pediatric Hodgkin disease

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7 January 2021

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

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7 January 2021

Nongenotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma

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7 January 2021

MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy

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7 January 2021

Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy

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7 January 2021

MDM2 is a central node in the p53 pathway: 12 years and counting

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7 January 2021

TP53 in hematological cancer: low incidence of mutations with significant clinical relevance

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7 January 2021

MDM2 gene amplification and lack of p53 point mutations in Hodgkin and Reed-Sternberg cells: results from single-cell polymerase chain reaction and molecular cytogenetic studies

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7 January 2021

TP53 gene mutations in Hodgkin lymphoma are infrequent and not associated with absence of Epstein-Barr virus

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7 January 2021

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

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7 January 2021

Inactivating I kappa B epsilon mutations in Hodgkin/Reed-Sternberg cells

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7 January 2021

Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation.

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7 January 2021

HSP90 and the chaperoning of cancer

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7 January 2021

Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells

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7 January 2021

A system for stable expression of short interfering RNAs in mammalian cells

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7 January 2021

P53 expression in Reed-Sternberg cells does not correlate with gene mutations in Hodgkin's disease

1 reference

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7 January 2021

Inhibition of NF-kappaB essentially contributes to arsenic-induced apoptosis.

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7 January 2021

p53 from complexity to simplicity: mutant p53 stabilization, gain-of-function, and dominant-negative effect

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7 January 2021

Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death

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7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2404565

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Dimensions Publication ID

18 September 2017

1014777338

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