Adaptive response to increased bile acids: induction of MDR1 gene expression and P-glycoprotein activity in renal epithelial cells (Q40164197)

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English	Adaptive response to increased bile acids: induction of MDR1 gene expression and P-glycoprotein activity in renal epithelial cells	scientific article

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PubMed publication ID

17333245

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18 September 2017

title

Adaptive response to increased bile acids: induction of MDR1 gene expression and P-glycoprotein activity in renal epithelial cells (English)

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Europe PubMed Central

PubMed publication ID

17333245

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18 September 2017

author name string

Carsten Kneuer

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1

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Europe PubMed Central

PubMed publication ID

17333245

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18 September 2017

Walther Honscha

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2

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Europe PubMed Central

PubMed publication ID

17333245

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18 September 2017

Gotthold Gäbel

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3

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Europe PubMed Central

PubMed publication ID

17333245

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18 September 2017

Kerstin U Honscha

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4

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Europe PubMed Central

PubMed publication ID

17333245

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18 September 2017

publication date

27 February 2007

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Europe PubMed Central

PubMed publication ID

17333245

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18 September 2017

published in

Pfluegers Archiv

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Europe PubMed Central

PubMed publication ID

17333245

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18 September 2017

volume

454

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Europe PubMed Central

PubMed publication ID

17333245

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18 September 2017

issue

4

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Europe PubMed Central

PubMed publication ID

17333245

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18 September 2017

page(s)

587-594

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Europe PubMed Central

PubMed publication ID

17333245

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18 September 2017

cites work

Bile acid regulation of hepatic physiology: III. Bile acids and nuclear receptors

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21 January 2018

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12 December 2020

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The renal transport of taurine and the regulation of renal sodium-chloride-dependent transporter activity

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

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Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

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Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

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Gene expression profiling of renal dysfunction in rats with experimental cirrhosis.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

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Biochemical and molecular pharmacological aspects of transporters as determinants of drug disposition

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

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Identification of a nuclear receptor for bile acids

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

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Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis.

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PubMed

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12 December 2020

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Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

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Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

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Regulation of the hepatic multidrug resistance gene expression by endotoxin and inflammatory cytokines in mice.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

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Adaptive regulation of bile salt transporters in kidney and liver in obstructive cholestasis in the rat

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

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Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

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Penetration of endogenous steroid hormones corticosterone, cortisol, aldosterone and progesterone into the brain is enhanced in mice deficient for both mdr1a and mdr1b P-glycoproteins

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

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Up-regulation of MDR1 function and expression by cisplatin in LLC-PK1 cells

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12 December 2020

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Impact of endotoxin-induced changes in P-glycoprotein expression on disposition of doxorubicin in mice.

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

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Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

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The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

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The UDCA dosage deficit: a fate shared with CDCA.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

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Range of serum bile acid concentrations in neonates, infants, older children, and in adults.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in the metabolism and disposition of ursodeoxycholic acid and of its taurine-conjugated species in patients with primary biliary cirrhosis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

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Regulation of glucose-transporter function

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haplotype analysis of ABCB1/MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

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Influence of different chemicals on MDR-1 P-glycoprotein expression and activity in the HK-2 proximal tubular cell line

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for constitutive androstane receptor in the regulation of human intestinal MDR1 expression

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of serum and urinary bile acids in patients with primary biliary cirrhosis by gas-liquid chromatography-mass spectrometry: effect of ursodeoxycholic acid treatment

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenomics of MDR1/ABCB1 gene: the influence on risk and clinical outcome of haematological malignancies

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the P-glycoprotein transporter MDR1(C3435T) polymorphism with the susceptibility to renal epithelial tumors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High expression of MDR1, MRP1, and MRP3 in the hepatic progenitor cell compartment and hepatocytes in severe human liver disease.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the bile salt export pump is maintained after chronic cholestasis in the rat.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced activity of 11 beta-hydroxysteroid dehydrogenase in patients with cholestasis

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in bile acid composition of serum and gallbladder bile in bile duct ligated dogs

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal elimination of p-aminohippurate (PAH) in response to three days of biliary obstruction in the rat. The role of OAT1 and OAT3

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

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Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

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Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

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Radioimmunoassay of conjugated cholic acid, chenodeoxycholic acid, and deoxycholic acid from human serum, with use of 125I-labeled ligands

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

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Expression of rat renal cortical OAT1 and OAT3 in response to acute biliary obstruction

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

based on heuristic

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Differential involvement of multidrug resistance-associated protein 1 and P-glycoprotein in tissue distribution and excretion of grepafloxacin in mice

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17333245

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12 December 2020

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Identifiers

DOI

10.1007/S00424-007-0235-1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17333245

retrieved

18 September 2017

PubMed publication ID

17333245

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17333245

retrieved

18 September 2017

 

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