Silencing of the type 1 insulin-like growth factor receptor increases the sensitivity to apoptosis and inhibits invasion in human lung adenocarcinoma A549 cells. (Q40116086)

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English	Silencing of the type 1 insulin-like growth factor receptor increases the sensitivity to apoptosis and inhibits invasion in human lung adenocarcinoma A549 cells.	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

17 September 2017

Silencing of the type 1 insulin-like growth factor receptor increases the sensitivity to apoptosis and inhibits invasion in human lung adenocarcinoma A549 cells (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275632&resulttype=core&format=json

13 May 2020

apoptotic process

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Zhiyuan Ma

1

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13 May 2020

Aiqiang Dong

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275632&resulttype=core&format=json

13 May 2020

Minjian Kong

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275632&resulttype=core&format=json

13 May 2020

Jianfang Qian

4

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13 May 2020

publication date

24 June 2007

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17 September 2017

Cellular & Molecular Biology Letters

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13 May 2020

12

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13 May 2020

4

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13 May 2020

556-572

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13 May 2020

RNA interference: listening to the sound of silence

1 reference

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21 January 2018

Matrix metalloproteinases in lung diseases

1 reference

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21 January 2018

Matrix metalloproteinases and metastasis

1 reference

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21 January 2018

Molecular and cellular aspects of the insulin-like growth factor I receptor

1 reference

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Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin

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Recombinant adenoviruses expressing dominant negative insulin-like growth factor-I receptor demonstrate antitumor effects on lung cancer.

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21 January 2018

Killing the messenger: short RNAs that silence gene expression

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RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo

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Effectiveness of insulin-like growth factor I receptor antisense strategy against Ewing's sarcoma cells

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Activation of the insulin-like growth factor-I receptor inhibits tumor necrosis factor-induced cell death

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Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals

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21 January 2018

A dominant negative type I insulin-like growth factor receptor inhibits metastasis of human cancer cells.

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21 January 2018

Personal experience in lung cancer sleeve lobectomy and sleeve pneumonectomy.

1 reference

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21 January 2018

Treatment of human breast cancer cells with antisense RNA to the type I insulin-like growth factor receptor inhibits cell growth, suppresses tumorigenesis, alters the metastatic potential, and prolongs survival in vivo.

1 reference

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21 January 2018

U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells.

1 reference

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21 January 2018

Blockade of the type I IGF receptor expression in human prostate cancer cells inhibits proliferation and invasion, up-regulates IGF binding protein-3, and suppresses MMP-2 expression

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Epidermal growth factor promotes invasiveness of pancreatic cancer cells through NF-kappaB-mediated proteinase productions

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21 January 2018

Cloning, expression and mapping of a novel human zinc-finger gene TCF17 homologous to rodent Kid1.

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Insulin-like Growth Factor I Increases αVβ3Affinity by Increasing the Amount of Integrin-associated Protein That Is Associated with Non-raft Domains of the Cellular Membrane

1 reference

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21 January 2018

Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone recepto

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Induction of tumor suppression and glandular differentiation of A549 lung carcinoma cells by dominant-negative IGF-I receptor

1 reference

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Genetic blockade of the insulin-like growth factor-I receptor: a promising strategy for human pancreatic cancer

1 reference

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Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation

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12 December 2020

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Insulin-like growth factor-I can mediate autocrine proliferation of human small cell lung cancer cell lines in vitro

1 reference

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Blockage of insulin-like growth factor-I receptor inhibits the growth of Ewing's sarcoma in athymic mice

1 reference

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12 December 2020

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Up-regulation of urokinase-type plasminogen activator by insulin-like growth factor-I depends upon phosphatidylinositol-3 kinase and mitogen-activated protein kinase kinase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17588222

12 December 2020

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The efficacy of small interfering RNAs targeted to the type 1 insulin-like growth factor receptor (IGF1R) is influenced by secondary structure in the IGF1R transcript

1 reference

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12 December 2020

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A prospective study of plasma levels of insulin-like growth factor I (IGF-I) and IGF-binding protein-3, and colorectal cancer risk among men

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Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17588222

12 December 2020

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Expression of collagenase-related metalloproteinase genes in human lung or head and neck tumours

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Clinical impact of the plasminogen activation system in tumor invasion and metastasis: prognostic relevance and target for therapy

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Matrix metalloproteinases and metastatic cancer.

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Selective suppression of matrix metalloproteinase-9 in human glioblastoma cells by antisense gene transfer impairs glioblastoma cell invasion

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Cancer statistics, 2000.

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1 reference

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Down-regulation of IGF-IR using small, interfering, hairpin RNA (siRNA) inhibits growth of human lung cancer cell line A549 in vitro and in nude mice

1 reference

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1 reference

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1 reference

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Antitumor effects of an adenovirus expressing antisense insulin-like growth factor I receptor on human lung cancer cell lines

1 reference

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Identifiers

10.2478/S11658-007-0022-1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275632&resulttype=core&format=json

13 May 2020

Dimensions Publication ID

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9 September 2019

https://scigraph.springernature.com/pub.10.2478/s11658-007-0022-1

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275632&resulttype=core&format=json

13 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6275632&resulttype=core&format=json

13 May 2020

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