Development and evaluation of peptidic ligands targeting tumour-associated urokinase plasminogen activator receptor (uPAR) for use in alpha-emitter therapy for disseminated ovarian cancer (Q40076948)

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English	Development and evaluation of peptidic ligands targeting tumour-associated urokinase plasminogen activator receptor (uPAR) for use in alpha-emitter therapy for disseminated ovarian cancer	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

17 September 2017

Development and evaluation of peptidic ligands targeting tumour-associated urokinase plasminogen activator receptor (uPAR) for use in alpha-emitter therapy for disseminated ovarian cancer (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

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Reingard Senekowitsch-Schmidtke

8

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Reingard Senekowitsch-Schmidtke

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Europe PubMed Central

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17 September 2017

10

object named as

Christof Seidl

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17 September 2017

Frank Bruchertseifer

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Frank Bruchertseifer

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17 September 2017

Alfred Morgenstern

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Alfred Morgenstern

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17 September 2017

author name string

Sebastian Knör

1

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PubMed publication ID

17 September 2017

Sumito Sato

2

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17 September 2017

Timo Huber

3

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Europe PubMed Central

PubMed publication ID

17 September 2017

Manfred Schmitt

6

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17 September 2017

Horst Kessler

7

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17 September 2017

Viktor Magdolen

9

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17 September 2017

language of work or name

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publication date

22 September 2007

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Europe PubMed Central

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17 September 2017

European Journal of Nuclear Medicine and Molecular Imaging

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Europe PubMed Central

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17 September 2017

35

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Europe PubMed Central

PubMed publication ID

17 September 2017

1

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Europe PubMed Central

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17 September 2017

53-64

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PubMed publication ID

17 September 2017

Receptor targeting for tumor localisation and therapy with radiopeptides

1 reference

https://api.crossref.org/works/10.1007%2FS00259-007-0582-3

21 January 2018

Establishment of new ovarian and colon carcinoma cell lines: differentiation is only possible by cytokeratin analysis

1 reference

https://api.crossref.org/works/10.1007%2FS00259-007-0582-3

21 January 2018

Receptor-mediated radionuclide therapy with 90Y-DOTATOC in association with amino acid infusion: a phase I study

1 reference

https://api.crossref.org/works/10.1007%2FS00259-007-0582-3

21 January 2018

Mitigation of radiation nephropathy after internal alpha-particle irradiation of kidneys

1 reference

https://api.crossref.org/works/10.1007%2FS00259-007-0582-3

21 January 2018

Inhibition of invasion, angiogenesis, tumor growth, and metastasis by adenovirus-mediated transfer of antisense uPAR and MMP-9 in non-small cell lung cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

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Multimeric cyclic RGD peptides as potential tools for tumor targeting: solid-phase peptide synthesis and chemoselective oxime ligation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-invasive visualisation of the development of peritoneal carcinomatosis and tumour regression after 213Bi-radioimmunotherapy using bioluminescence imaging

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

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A comparison of high- versus low-linear energy transfer somatostatin receptor targeted radionuclide therapy in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

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Combination radionuclide therapy using 177Lu- and 90Y-labeled somatostatin analogs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

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Local targeting of malignant gliomas by the diffusible peptidic vector 1,4,7,10-tetraazacyclododecane-1-glutaric acid-4,7,10-triacetic acid-substance p.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Candidates for peptide receptor radiotherapy today and in the future.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer radioimmunotherapy with alpha-emitting nuclides

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death triggered by alpha-emitting 213Bi-immunoconjugates in HSC45-M2 gastric cancer cells is different from apoptotic cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the tumor-associated urokinase-type plasminogen activation system: effects of high-level synthesis of soluble urokinase receptor in ovarian and breast cancer cells in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global cancer statistics, 2002

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the interaction of urokinase-type plasminogen activator (uPA) with its receptor (uPAR) by synthetic peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urokinase-type plasminogen activator (uPA) and its inhibitor PAI-I: novel tumor-derived factors with a high prognostic and predictive impact in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activation and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-radioimmunotherapy of intraperitoneally growing OVCAR-3 tumors of variable dimensions: Outcome related to measured tumor size and mean absorbed dose.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxicity of PAI2, C595 and Herceptin vectors labeled with the alpha-emitting radioisotope Bismuth-213 for ovarian cancer cell monolayers and clusters

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Locoregional alpha-radioimmunotherapy of intraperitoneal tumor cell dissemination using a tumor-specific monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody-targeted radiation cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal uptake of radiolabeled octreotide in human subjects is efficiently inhibited by succinylated gelatin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

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Highly specific tumor binding of a 213Bi-labeled monoclonal antibody against mutant E-cadherin suggests its usefulness for locoregional alpha-radioimmunotherapy of diffuse-type gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The urokinase plasminogen activator receptor as a gene therapy target for cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis, solution structure, and biological evaluation of urokinase type plasminogen activator (uPA)-derived receptor binding domain mimetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptide-derived antagonists of the urokinase receptor. affinity maturation by combinatorial chemistry, identification of functional epitopes, and inhibitory effect on cancer cell intravasation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical studies of bismuth-213 labeled plasminogen activator inhibitor type 2 (PAI2) in a prostate cancer nude mouse xenograft model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urokinase-type plasminogen activator (uPA) and its receptor (uPAR): development of antagonists of uPA/uPAR interaction and their effects in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted alpha particle immunotherapy for myeloid leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advances in cancer therapy with radiolabeled monoclonal antibodies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical evaluation of 213Bi-labeled plasminogen activator inhibitor type 2 in an orthotopic murine xenogenic model of human breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lutetium-177-labeled gastrin releasing peptide receptor binding analogs: a novel approach to radionuclide therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of Ac-225 from Th-229 for targeted alpha therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre-clinical study of 213Bi labeled PAI2 for the control of micrometastatic pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid, single vessel method for preparation of clinical grade ligand conjugated monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The urokinase receptor as a potential target in cancer therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular targeting with peptides or peptide-polymer conjugates: just a question of size?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survival of women with advanced ovarian cancer and complete pathologic response at second-look laparotomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptide receptors as molecular targets for cancer diagnosis and therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bifunctional ligands that target cells displaying the alpha v beta3 integrin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overview of results of peptide receptor radionuclide therapy with 3 radiolabeled somatostatin analogs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

213Bi-[DOTA0, Tyr3]octreotide peptide receptor radionuclide therapy of pancreatic tumors in a preclinical animal model

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of rat breast cancer metastasis and reduction of primary tumour growth by the small synthetic urokinase inhibitor WX-UK1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peritoneal carcinomatosis from non-gynecologic malignancies: results of the EVOCAPE 1 multicentric prospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gelatin-based plasma expander effectively reduces renal uptake of 111In-octreotide in mice and rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of polyglutamic acids to reduce uptake of radiometal-labeled minigastrin in the kidneys.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted actinium-225 in vivo generators for therapy of ovarian cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Lys40(Ahx-DTPA-111In)NH2]exendin-4, a very promising ligand for glucagon-like peptide-1 (GLP-1) receptor targeting.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiolabeled somatostatin receptor antagonists are preferable to agonists for in vivo peptide receptor targeting of tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

213Bi-radioimmunotherapy defeats early-stage disseminated gastric cancer in nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal toxicity after radionuclide therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of urokinase-type plasminogen-activator (upa) and its receptor (upar) in human ovarian-cancer cells and in-vitro invasion capacity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclo19,31[D-Cys19]-uPA19-31 is a potent competitive antagonist of the interaction of urokinase-type plasminogen activator with its receptor (CD87)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative analysis of the effect of probenecid on pharmacokinetics of 99mTc-mercaptoacetyltriglycine in dogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radioimmunotherapy with alpha-particle emitting radionuclides.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The uPA/uPA receptor system as a target for tumor therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radioimmunotherapy of human colon carcinoma xenografts using a 213Bi-labeled domain-deleted humanized monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safe and effective inhibition of renal uptake of radiolabelled octreotide by a combination of lysine and arginine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intralesional targeted alpha therapy for metastatic melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17891393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00259-007-0582-3

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

release_n2qkx2xiobgyhnp23nfkt3yu5e

1 reference

https://api.fatcat.wiki/v0/release/n2qkx2xiobgyhnp23nfkt3yu5e

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

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