Pax-6 and c-Maf functionally interact with the alpha-cell-specific DNA element G1 in vivo to promote glucagon gene expression (Q40075050)

17 September 2017

title

Pax-6 and c-Maf functionally interact with the alpha-cell-specific DNA element G1 in vivo to promote glucagon gene expression (English)

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17 September 2017

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Yvan Gosmain

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17 September 2017

Isabelle Avril

series ordinal

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17 September 2017

Aline Mamin

series ordinal

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17 September 2017

Jacques Philippe

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17 September 2017

language of work or name

English

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publication date

27 September 2007

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Journal of Biological Chemistry

17 September 2017

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inferred from page(s)

published in

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17 September 2017

volume

282

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17 September 2017

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17 September 2017

page(s)

35024-35034

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Structure and pancreatic expression of the insulin and glucagon genes

17 September 2017

cites work

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Alpha-cell-specific expression of the glucagon gene is conferred to the glucagon promoter element by the interactions of DNA-binding proteins

21 January 2018

1 reference

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Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element

21 January 2018

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Islet-specific proteins interact with the insulin-response element of the glucagon gene

21 January 2018

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Homologous DNA sequences and cellular factors are implicated in the control of glucagon and insulin gene expression

21 January 2018

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Activation of proglucagon gene transcription through a novel promoter element by the caudal-related homeodomain protein cdx-2/3.

21 January 2018

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Interaction of Maf transcription factors with Pax-6 results in synergistic activation of the glucagon promoter

21 January 2018

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POU Domain Transcription Factor brain 4 Confers Pancreatic α-Cell-Specific Expression of the Proglucagon Gene Through Interaction with a Novel Proximal Promoter G1 Element

21 January 2018

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Pax-QNR/Pax-6, a paired box- and homeobox-containing gene expressed in neurons, is also expressed in pancreatic endocrine cells

21 January 2018

1 reference

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Pax-6 and Cdx-2/3 interact to activate glucagon gene expression on the G1 control element

21 January 2018

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21 January 2018

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Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells

21 January 2018

1 reference

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Differentially expressed Maf family transcription factors, c-Maf and MafA, activate glucagon and insulin gene expression in pancreatic islet alpha- and beta-cells

21 January 2018

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MafB: an activator of the glucagon gene expressed in developing islet alpha- and beta-cells.

21 January 2018

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MafB is required for islet beta cell maturation

21 January 2018

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The role of Brn4/Pou3f4 and Pax6 in forming the pancreatic glucagon cell identity

21 January 2018

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Insulin gene transcription is decreased rapidly by lowering glucose concentrations in rat islet cells

21 January 2018

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Transformation of rat cells by DNA of human adenovirus 5

21 January 2018

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Analysis of chromatin structure by in vivo formaldehyde cross-linking.

21 January 2018

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Insulin inhibits hepatocellular glucose production by utilizing liver-enriched transcriptional inhibitory protein to disrupt the association of CREB-binding protein and RNA polymerase II with the phosphoenolpyruvate carboxykinase gene promoter

21 January 2018

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Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development

21 January 2018

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Redundant and synergistic effect of Cdx-2 and Brn-4 on regulating proglucagon gene expression

21 January 2018

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Glucagon gene transcription activation mediated by synergistic interactions of pax-6 and cdx-2 with the p300 co-activator

21 January 2018

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Pax6 and Cdx2/3 form a functional complex on the rat glucagon gene promoter G1-element

21 January 2018

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A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells

21 January 2018

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Potential roles of large mafs in cell lineages and developing pancreas.

21 January 2018

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Tissue-specific regulation of the mouse alphaA-crystallin gene in lens via recruitment of Pax6 and c-Maf to its promoter

21 January 2018

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MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun.

21 January 2018

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beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

21 January 2018

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The pancreatic beta-cell-specific transcription factor Pax-4 inhibits glucagon gene expression through Pax-6.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M702795200

Ectopic expression of the beta-cell specific transcription factor Pdx1 inhibits glucagon gene transcription

21 January 2018

1 reference

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Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation

21 January 2018

1 reference

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The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702795200

The beta-cell specific transcription factor Nkx6.1 inhibits glucagon gene transcription by interfering with Pax6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702795200

Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702795200

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702795200

21 January 2018

Identifiers

DOI

10.1074/JBC.M702795200

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17 September 2017

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