Relationship of the human immunodeficiency virus type 1 gp120 third variable loop to a component of the CD4 binding site in the fourth conserved region (Q40061779)

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scientific article published on December 1, 1992

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English	Relationship of the human immunodeficiency virus type 1 gp120 third variable loop to a component of the CD4 binding site in the fourth conserved region	scientific article published on December 1, 1992

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scholarly article

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17 September 2017

Relationship of the human immunodeficiency virus type 1 gp120 third variable loop to a component of the CD4 binding site in the fourth conserved region (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1279195

8 September 2022

Joseph Sodroski

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Sodroski J

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17 September 2017

Richard T. Wyatt

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Wyatt R

R. Wyatt

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17 September 2017

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8 September 2022

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M. Thali

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8 September 2022

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S. Tilley

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8 September 2022

A. Pinter

4

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8 September 2022

M. Posner

5

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8 September 2022

D. Ho

6

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8 September 2022

J. Robinson

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8 September 2022

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publication date

1 December 1992

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17 September 2017

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1279195/?tool=EBI

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8 September 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1279195/pdf/?tool=EBI

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8 September 2022

http://jvi.asm.org/cgi/content/abstract/66/12/6997

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8 September 2022

https://europepmc.org/articles/PMC240347

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1279195

8 September 2022

https://europepmc.org/articles/PMC240347?pdf=render

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Europe PubMed Central

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8 September 2022

Journal of Virology

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17 September 2017

66

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Europe PubMed Central

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17 September 2017

12

1 reference

Europe PubMed Central

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17 September 2017

6997-7004

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

1 reference

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Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

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22 September 2017

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

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22 September 2017

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

1 reference

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22 September 2017

Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1

1 reference

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Purified envelope glycoproteins from human immunodeficiency virus type 1 variants induce individual, type-specific neutralizing antibodies

1 reference

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22 September 2017

A soluble form of CD4 (T4) protein inhibits AIDS virus infection

1 reference

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22 September 2017

Prospect for prevention of human immunodeficiency virus infection: purified 120-kDa envelope glycoprotein induces neutralizing antibody

1 reference

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22 September 2017

Neutralizing antibodies to an immunodominant envelope sequence do not prevent gp120 binding to CD4.

1 reference

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22 September 2017

HIV infection is blocked in vitro by recombinant soluble CD4.

1 reference

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22 September 2017

Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein

1 reference

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22 September 2017

Functional interaction of constant and variable domains of human immunodeficiency virus type 1 gp120.

1 reference

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22 September 2017

Characterization of HIV-1 neutralization escape mutants

1 reference

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22 September 2017

Effects of anti-gp120 monoclonal antibodies on CD4 receptor binding by the env protein of human immunodeficiency virus type 1

1 reference

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22 September 2017

Characterization of a human immunodeficiency virus neutralizing monoclonal antibody and mapping of the neutralizing epitope

1 reference

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22 September 2017

Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=240347

22 September 2017

A soluble recombinant polypeptide comprising the amino-terminal half of the extracellular region of the CD4 molecule contains an active binding site for human immunodeficiency virus

1 reference

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22 September 2017

Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides

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22 September 2017

Persistent infection of chimpanzees with human immunodeficiency virus: serological responses and properties of reisolated viruses.

1 reference

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22 September 2017

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

1 reference

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22 September 2017

Restricted neutralization of divergent human T-lymphotropic virus type III isolates by antibodies to the major envelope glycoprotein

1 reference

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22 September 2017

Variable and conserved neutralization antigens of human immunodeficiency virus

1 reference

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22 September 2017

Binding of the human retrovirus HTLV-III/LAV/ARV/HIV to the CD4 (T4) molecule: conformation dependence, epitope mapping, antibody inhibition, and potential for idiotypic mimicry

1 reference

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22 September 2017

Emergence of viruses resistant to neutralization by V3-specific antibodies in experimental human immunodeficiency virus type 1 IIIB infection of chimpanzees.

1 reference

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22 September 2017

Antibody-mediated in vitro neutralization of human immunodeficiency virus type 1 abolishes infectivity for chimpanzees

1 reference

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22 September 2017

Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells

1 reference

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22 September 2017

Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants

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22 September 2017

Changes in the transmembrane region of the human immunodeficiency virus type 1 gp41 envelope glycoprotein affect membrane fusion.

1 reference

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22 September 2017

Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding

1 reference

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22 September 2017

Characterization of the fusion domain of the human immunodeficiency virus type 1 envelope glycoprotein gp41

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Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160.

1 reference

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22 September 2017

Evidence for non-V3-specific neutralizing antibodies that interfere with gp120/CD4 binding in human immunodeficiency virus 1-infected humans

1 reference

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Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein

1 reference

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Immunization of chimpanzees confers protection against challenge with human immunodeficiency virus

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Identification of the principal neutralizing determinant of human immunodeficiency virus type 1 as a fusion domain

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A broadly neutralizing monoclonal antibody that recognizes the V3 region of human immunodeficiency virus type 1 glycoprotein gp120.

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Effects of changes in gp120-CD4 binding affinity on human immunodeficiency virus type 1 envelope glycoprotein function and soluble CD4 sensitivity

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Analysis of mutations in the V3 domain of gp160 that affect fusion and infectivity

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Native but not denatured recombinant human immunodeficiency virus type 1 gp120 generates broad-spectrum neutralizing antibodies in baboons

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Characterization of a discontinuous human immunodeficiency virus type 1 gp120 epitope recognized by a broadly reactive neutralizing human monoclonal antibody

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Conformational changes induced in the human immunodeficiency virus envelope glycoprotein by soluble CD4 binding

1 reference

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Conformational epitope on gp120 important in CD4 binding and human immunodeficiency virus type 1 neutralization identified by a human monoclonal antibody

1 reference

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Attenuation of human immunodeficiency virus type 1 cytopathic effect by a mutation affecting the transmembrane envelope glycoprotein

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Mutations in the principal neutralization determinant of human immunodeficiency virus type 1 affect syncytium formation, virus infectivity, growth kinetics, and neutralization

1 reference

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Discontinuous, conserved neutralization epitopes overlapping the CD4-binding region of human immunodeficiency virus type 1 gp120 envelope glycoprotein

1 reference

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pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane

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Characterization of envelope and core structural gene products of HTLV-III with sera from AIDS patients

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Soluble CD4 molecules neutralize human immunodeficiency virus type 1.

1 reference

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Human immunodeficiency virus 1. Predominance of a group-specific neutralizing epitope that persists despite genetic variation

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HTLV-III/LAV-neutralizing antibodies to an E. coli-produced fragment of the virus envelope

1 reference

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15 June 2018

Effects on CD4 binding of anti-peptide sera to the fourth and fifth conserved domains of HIV-1 gp120.

1 reference

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The V3 loops of the HIV-1 and HIV-2 surface glycoproteins contain proteolytic cleavage sites: a possible function in viral fusion?

1 reference

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Alteration of HIV-1 infectivity and neutralization by a single amino acid replacement in the V3 loop domain

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Prevention of HIV-1 infection in chimpanzees by gpl20 V3 domain-specific monoclonal antibody

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Functional roles of the V3 hypervariable region of HIV-1 gp160 in the processing of gp160 and in the formation of syncytia in CD4+ cells

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A human monoclonal antibody against the CD4-binding site of HIV1 gp120 exhibits potent, broadly neutralizing activity

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Neutralization of Divergent HIV-1 Isolates by Conformation-Dependent Human Antibodies to Gp120

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An IgG human monoclonal antibody that reacts with HIV-1/GP120, inhibits virus binding to cells, and neutralizes infection

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Broadly neutralizing antibodies elicited by the hypervariable neutralizing determinant of HIV-1.

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Identification of Conserved and Variant Epitopes of Human Immunodeficiency Virus Type 1 (HIV-1) gp120 by Human Monoclonal Antibodies Produced by EBV-Transformed Cell Lines

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Epitopes recognized by the neutralizing antibodies of an HIV-1-infected individual

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Cooperativity of neutralizing antibodies directed against the V3 and CD4 binding regions of the human immunodeficiency virus gp120 envelope glycoprotein

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Amino acid residues of the human immunodeficiency virus type I gp120 critical for the binding of rat and human neutralizing antibodies that block the gp120-sCD4 interaction

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Synergistic neutralization of HIV-1 by human monoclonal antibodies against the V3 loop and the CD4-binding site of gp120

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Characteristics of a neutralizing monoclonal antibody to the HIV envelope glycoprotein.

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Neutralizing cross-reactive and non-neutralizing monoclonal antibodies to HIV-1 gp120.

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Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III.

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Conserved sequence and structural elements in the HIV-1 principal neutralizing determinant

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20 August 2018

Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. Evidence for a selective defect in soluble antigen recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/1279195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking of HIV-1 infectivity by a soluble, secreted form of the CD4 antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/1279195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single amino-acid changes in HIV envelope affect viral tropism and receptor binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/1279195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A soluble CD4 protein selectively inhibits HIV replication and syncytium formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/1279195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergy between human monoclonal antibodies to HIV extends their effective biologic activity against homologous and divergent strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/1279195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.66.12.6997-7004.1992

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 September 2017

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