Potent upregulation of glutathione and NAD(P)H:quinone oxidoreductase 1 by alpha-lipoic acid in human neuroblastoma SH-SY5Y cells: protection against neurotoxicant-elicited cytotoxicity (Q40066980)

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English	Potent upregulation of glutathione and NAD(P)H:quinone oxidoreductase 1 by alpha-lipoic acid in human neuroblastoma SH-SY5Y cells: protection against neurotoxicant-elicited cytotoxicity	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

17 September 2017

Potent upregulation of glutathione and NAD(P)H:quinone oxidoreductase 1 by alpha-lipoic acid in human neuroblastoma SH-SY5Y cells: protection against neurotoxicant-elicited cytotoxicity (English)

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Europe PubMed Central

PubMed publication ID

17 September 2017

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author name string

Zhenquan Jia

1

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Europe PubMed Central

PubMed publication ID

17 September 2017

Seema Hallur

2

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Europe PubMed Central

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17 September 2017

Hong Zhu

3

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Europe PubMed Central

PubMed publication ID

17 September 2017

Yunbo Li

4

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Europe PubMed Central

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17 September 2017

Hara P Misra

5

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17 September 2017

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17 October 2007

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Europe PubMed Central

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17 September 2017

Neurochemical Research

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Europe PubMed Central

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17 September 2017

33

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Europe PubMed Central

PubMed publication ID

17 September 2017

5

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Europe PubMed Central

PubMed publication ID

17 September 2017

790-800

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Europe PubMed Central

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17 September 2017

Oxidative stress and nitration in neurodegeneration: cause, effect, or association?

1 reference

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The pharmacology of the antioxidant lipoic acid

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Conjugates of catecholamines with cysteine and GSH in Parkinson's disease: possible mechanisms of formation involving reactive oxygen species.

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The Role of Chemically Induced Glutathione and Glutathione S-Transferase in Protecting Against 4-Hydroxy-2-Nonenal- Mediated Cytotoxicity in Vascular Smooth Muscle Cells

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12 December 2020

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Alpha-lipoic acid: a metabolic antioxidant and potential redox modulator of transcription.

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12 December 2020

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Prevention of hypertension, insulin resistance, and oxidative stress by alpha-lipoic acid

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12 December 2020

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Peroxynitrite in the pathogenesis of Parkinson's disease and the neuroprotective role of metallothioneins

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12 December 2020

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Investigations on the pharmacokinetics of alpha-lipoic acid in healthy volunteers

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Peroxynitrite-induced cytotoxicity: mechanism and opportunities for intervention

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12 December 2020

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Neuroprotection by the metabolic antioxidant alpha-lipoic acid

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Dose-proportionality of oral thioctic acid--coincidence of assessments via pooled plasma and individual data

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Induction of cellular glutathione and glutathione S-transferase by 3H-1,2-dithiole-3-thione in rat aortic smooth muscle A10 cells: protection against acrolein-induced toxicity

1 reference

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12 December 2020

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Metallothionein inhibits peroxynitrite-induced DNA and lipoprotein damage

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12 December 2020

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Structure-activity relationships for growth inhibition and induction of apoptosis by 4-hydroxy-2-nonenal in raw 264.7 cells

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Glutathione: an overview of biosynthesis and modulation

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Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial.

1 reference

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12 December 2020

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Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid

1 reference

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12 December 2020

based on heuristic

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Parkinson's disease: clinical signs and symptoms, neural mechanisms, positron emission tomography, and therapeutic interventions

1 reference

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12 December 2020

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Nrf2 controls bone marrow stromal cell susceptibility to oxidative and electrophilic stress

1 reference

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12 December 2020

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Induction of endogenous glutathione by the chemoprotective agent, 3H-1,2-dithiole-3-thione, in human neuroblastoma SH-SY5Y cells affords protection against peroxynitrite-induced cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

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Catalase in vitro

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12 December 2020

based on heuristic

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Reactive oxygen species and reactive nitrogen species: relevance to cyto(neuro)toxic events and neurologic disorders. An overview.

1 reference

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12 December 2020

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Glutathione transferases

1 reference

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12 December 2020

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Upregulation of endogenous glutathione system by 3H-1,2-dithiole-3-thione in pancreatic RINm5F beta-cells as a novel strategy for protecting against oxidative beta-cell injury

1 reference

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12 December 2020

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4-hydroxynonenal as a bioactive marker of pathophysiological processes

1 reference

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12 December 2020

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Alpha-lipoic acid differently affects the reserpine-induced oxidative stress in the striatum and prefrontal cortex of rat brain

1 reference

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12 December 2020

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The molecular effects of acrolein

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Glutathione S-transferases. The first enzymatic step in mercapturic acid formation

1 reference

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12 December 2020

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Oxidation of ubiquinol by peroxynitrite: implications for protection of mitochondria against nitrosative damage

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effects of alpha-lipoic acid and its enantiomers demonstrated in rodent models of focal cerebral ischemia

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione and catalase provide overlapping defenses for protection against hydrogen peroxide in the yeast Saccharomyces cerevisiae.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison between the antioxidant and peroxynitrite-scavenging functions of the vitamin E metabolites alpha- and gamma-carboxyethyl-6-hydroxychromans

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

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Antioxidants and phase 2 enzymes in cardiomyocytes: Chemical inducibility and chemoprotection against oxidant and simulated ischemia-reperfusion injury

1 reference

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12 December 2020

based on heuristic

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Glutathione Peroxidase Protects against Peroxynitrite-mediated Oxidations

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-lipoic acid: a multifunctional antioxidant that improves insulin sensitivity in patients with type 2 diabetes

1 reference

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12 December 2020

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Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease.

1 reference

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12 December 2020

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Alpha-lipoic acid inhibits glycogen synthesis in rat soleus muscle via its oxidative activity and the uncoupling of mitochondria.

1 reference

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Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity

1 reference

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Possible roles of nitric oxide in the physiology and pathophysiology of the mammalian cochlea

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inferred from PubMed ID database lookup

Antioxidant and prooxidant activities of alpha-lipoic acid and dihydrolipoic acid

1 reference

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Pesticide exposure on southwestern Taiwanese with MnSOD and NQO1 polymorphisms is associated with increased risk of Parkinson's disease

1 reference

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12 December 2020

based on heuristic

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NAD(P)H:quinone oxidoreductase 1: role as a superoxide scavenger

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effects of alpha-lipoic acid and its positively charged amide analogue

1 reference

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Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbolester-induced differentiation

1 reference

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based on heuristic

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Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease

1 reference

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12 December 2020

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Automated assays for superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase activity.

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Expression of a melanocyte phenotype in human neuroblastoma cells in vitro

1 reference

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Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients

1 reference

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based on heuristic

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Cyclic AMP and cyclic GMP independent stimulation of ventricular calcium current by peroxynitrite donors in guinea pig myocytes

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A fluorometric method for determination of oxidized and reduced glutathione in tissues

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinone reductases multitasking in the metabolic world

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: protection against reactive oxygen and nitrogen species-induced cell injury

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-lipoic acid does not acutely affect resistance and conduit artery function or oxidative stress in healthy men.

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assays of glutathione peroxidase

1 reference

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12 December 2020

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Free radicals as mediators of tissue injury and disease

1 reference

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12 December 2020

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Long-term safety of alpha-lipoic acid (ALA) consumption: A 2-year study

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple pathways of peroxynitrite cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pain and sensory symptoms in Parkinson's disease

1 reference

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12 December 2020

based on heuristic

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Coenzyme Q10: a review of its promise as a neuroprotectant.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre-treatment with R-lipoic acid alleviates the effects of GSH depletion in PC12 cells: implications for Parkinson's disease therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress as a cause of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Reduction of α-Tocopherolquinone by Human NAD(P)H:Quinone Oxidoreductase: The Role of α-Tocopherolhydroquinone as a Cellular Antioxidant

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An assay for superoxide dismutase activity in mammalian tissue homogenates

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipoic acid increases glutathione production and enhances the effect of mercury in human cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson's Disease Research Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17940886

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11064-007-9496-5

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Europe PubMed Central

PubMed publication ID

17 September 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 September 2017

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