Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1. (Q40043123)

16 September 2017

title

Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1. (English)

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16 September 2017

Tom H M Ottenhoff

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16 September 2017

Annemieke Geluk

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16 September 2017

Hermen Overkleeft

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16 September 2017

Coenraad Kuijl

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16 September 2017

Nigel D L Savage

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16 September 2017

Marije Marsman

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16 September 2017

Adriaan W Tuin

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16 September 2017

Lennert Janssen

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16 September 2017

David A Egan

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16 September 2017

Mirjam Ketema

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16 September 2017

Rian van den Nieuwendijk

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16 September 2017

Susan J F van den Eeden

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16 September 2017

Alex Poot

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16 September 2017

Gijs van der Marel

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16 September 2017

Roderick L Beijersbergen

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16 September 2017

Jacques Neefjes

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16 September 2017

language of work or name

English

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publication date

1 November 2007

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16 September 2017

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16 September 2017

volume

450

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16 September 2017

issue

7170

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16 September 2017

page(s)

725-730

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Molecular mechanisms that confer antibacterial drug resistance

16 September 2017

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Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP

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Salmonella enterica serovar Typhimurium infection induces cyclooxygenase 2 expression in macrophages: involvement of Salmonella pathogenicity island 2.

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Protein kinase A, which regulates intracellular transport, forms complexes with molecular motors on organelles

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Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity

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A large-scale RNAi screen in human cells identifies new components of the p53 pathway

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7 January 2021

Genome-wide RNAi screen for host factors required for intracellular bacterial infection

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Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection

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Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis

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A structural comparison of inhibitor binding to PKB, PKA and PKA-PKB chimera

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A tale of two lipids: Mycobacterium tuberculosis phagosome maturation arrest.

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7 January 2021

PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection.

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7 January 2021

Salmonella modulates vesicular traffic by altering phosphoinositide metabolism

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7 January 2021

The Salmonella effector protein SopB protects epithelial cells from apoptosis by sustained activation of Akt.

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7 January 2021

Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis

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7 January 2021

PAK4 is activated via PI3K in HGF-stimulated epithelial cells

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7 January 2021

PAK4 mediates morphological changes through the regulation of GEF-H1

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7 January 2021

Activated PAK4 regulates cell adhesion and anchorage-independent growth

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7 January 2021

A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium

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7 January 2021

Rab14 is critical for maintenance of Mycobacterium tuberculosis phagosome maturation arrest

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RabD, a Dictyostelium Rab14-related GTPase, regulates phagocytosis and homotypic phagosome and lysosome fusion

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7 January 2021

AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domain

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Subversion of phosphoinositide metabolism by intracellular bacterial pathogens

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Handicapping the race to develop inhibitors of the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway

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7 January 2021

Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation

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7 January 2021

Short cytoplasmic sequences serve as retention signals for transmembrane proteins in the endoplasmic reticulum

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7 January 2021

Selective photolabeling of proteins using photoactivatable GFP.

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7 January 2021

A system for stable expression of short interfering RNAs in mammalian cells

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7 January 2021

Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking

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7 January 2021

Insulin disrupts beta-adrenergic signalling to protein kinase A in adipocytes

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7 January 2021

Biochemical characterization and cellular localization of a formalin-resistant melanoma-associated antigen reacting with monoclonal antibody NKI/C-3.

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7 January 2021

Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria

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7 January 2021

The rab7 GTPase controls the maturation of Salmonella typhimurium-containing vacuoles in HeLa cells

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7 January 2021

Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape.

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7 January 2021

Rapid screening method for the detection of antimicrobial substances

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7 January 2021

Comparison of methods based on different molecular epidemiological markers for typing of Mycobacterium tuberculosis complex strains: interlaboratory study of discriminatory power and reproducibility.

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7 January 2021

CellProfiler: image analysis software for identifying and quantifying cell phenotypes

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7 January 2021

RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase

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7 January 2021

Catalysis of guanine nucleotide exchange of Ran by RCC1 and stimulation of hydrolysis of Ran-bound GTP by Ran-GAP1.

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7 January 2021

A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling

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7 January 2021

The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors

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7 January 2021

Analysis of cell-based RNAi screens.

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7 January 2021

Statistical practice in high-throughput screening data analysis

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7 January 2021

Identifiers

DOI

10.1038/NATURE06345

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Dimensions Publication ID

16 September 2017

1014884721

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