Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process (Q40033262)

16 September 2017

title

Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process (English)

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16 September 2017

main subject

protein ubiquitination

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Orane Visvikis

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Patrick Lorès

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Laurent Boyer

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Emmanuel Lemichez

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Pierre Chardin

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16 September 2017

Gérard Gacon

series ordinal

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16 September 2017

language of work or name

English

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publication date

17 December 2007

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16 September 2017

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16 September 2017

volume

275

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16 September 2017

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16 September 2017

page(s)

386-396

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Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking

16 September 2017

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Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b

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Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

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Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells

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Proteasomal degradation of cytotoxic necrotizing factor 1-activated rac.

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Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

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21 January 2018

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Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases

21 January 2018

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21 January 2018

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21 January 2018

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Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change

21 January 2018

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Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch

21 January 2018

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A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways

21 January 2018

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POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.

21 January 2018

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10.1111/J.1742-4658.2007.06209.X

21 January 2018

Identifiers

DOI

1 reference

16 September 2017

1 reference