beta-arrestin-biased agonism at the beta2-adrenergic receptor (Q40034384)

16 September 2017

title

beta-arrestin-biased agonism at the beta2-adrenergic receptor (English)

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16 September 2017

Robert J Lefkowitz

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16 September 2017

Matthew T Drake

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16 September 2017

Jonathan D Violin

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16 September 2017

Erin J Whalen

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16 September 2017

James W Wisler

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16 September 2017

Sudha K Shenoy

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16 September 2017

language of work or name

English

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publication date

17 December 2007

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Journal of Biological Chemistry

16 September 2017

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inferred from page(s)

published in

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16 September 2017

volume

283

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16 September 2017

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16 September 2017

page(s)

5669-5676

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beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor

16 September 2017

cites work

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Structure and conformational changes in the C-terminal domain of the beta2-adrenoceptor: insights from fluorescence resonance energy transfer studies

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11 October 2022

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The G protein-coupled receptor repertoires of human and mouse

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New roles for beta-arrestins in cell signaling: not just for seven-transmembrane receptors

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beta2-adrenergic receptor signaling and desensitization elucidated by quantitative modeling of real time cAMP dynamics

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Pharmacological proteus?

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11 October 2022

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Target validation of G-protein coupled receptors

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11 October 2022

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Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor

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11 October 2022

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Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling

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11 October 2022

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Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor

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11 October 2022

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Transduction of receptor signals by beta-arrestins

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11 October 2022

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Cardiac-specific overexpression of AT1 receptor mutant lacking G alpha q/G alpha i coupling causes hypertrophy and bradycardia in transgenic mice.

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Distribution of a glycosylphosphatidylinositol-anchored protein at the apical surface of MDCK cells examined at a resolution of <100 A using imaging fluorescence resonance energy transfer

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11 October 2022

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Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus

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beta-arrestins: traffic cops of cell signaling

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11 October 2022

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Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

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11 October 2022

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Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation.

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11 October 2022

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Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.

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11 October 2022

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A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling

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11 October 2022

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Regulation of beta-adrenergic receptor signaling by S-nitrosylation of G-protein-coupled receptor kinase 2

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Beta-arrestin-biased ligands at seven-transmembrane receptors

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Missing links: mechanisms of protean agonism

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11 October 2022

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Fluorescent indicators of cAMP and Epac activation reveal differential dynamics of cAMP signaling within discrete subcellular compartments

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M708118200

Beta-arrestins and cell signaling

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M708118200

Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M708118200

G-protein signaling: back to the future

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11 October 2022

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Side-chain substitutions within angiotensin II reveal different requirements for signaling, internalization, and phosphorylation of type 1A angiotensin receptors.

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M708118200

Characterization of agonist stimulation of cAMP-dependent protein kinase and G protein-coupled receptor kinase phosphorylation of the beta2-adrenergic receptor using phosphoserine-specific antibodies

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M708118200

New concepts in drug discovery: collateral efficacy and permissive antagonism

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M708118200

Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M708118200

G-protein-coupled receptor kinase specificity for beta-arrestin recruitment to the beta2-adrenergic receptor revealed by fluorescence resonance energy transfer

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M708118200

Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M708118200

G proteins: transducers of receptor-generated signals

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M708118200

Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M708118200

Agonist and inverse agonist actions of beta-blockers at the human beta 2-adrenoceptor provide evidence for agonist-directed signaling

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M708118200

Identifiers

DOI

10.1074/JBC.M708118200

1 reference

16 September 2017

1 reference