Proinsulin peptide immunotherapy in type 1 diabetes: report of a first-in-man Phase I safety study. (Q40023867)

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17 January 2020

title

Proinsulin peptide immunotherapy in type 1 diabetes: report of a first-in-man Phase I safety study (English)

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17 January 2020

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17 January 2020

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17 January 2020

Biliana Lozanoska-Ochser

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17 January 2020

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17 January 2020

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17 January 2020

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17 January 2020

S L Thrower

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17 January 2020

K M Green

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17 January 2020

S Arif

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17 January 2020

J S Allen

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17 January 2020

C Van-Krinks

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17 January 2020

L Marquesini

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17 January 2020

S Brown

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publication date

20 November 2008

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Clinical and Experimental Immunology

17 January 2020

published in

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volume

155

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issue

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17 January 2020

page(s)

156-165

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Islet antigen specific IL-10+ immune responses but not CD4+CD25+FoxP3+ cells at diagnosis predict glycemic control in type 1 diabetes

17 January 2020

cites work

1 reference

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Update on the current status of peptide immunotherapy

14 September 2018

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Translational mini-review series on type 1 diabetes: Immune-based therapeutic approaches for type 1 diabetes

14 September 2018

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Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes

14 September 2018

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Induction of interleukin-10 and suppressor of cytokine signalling-3 gene expression following peptide immunotherapy.

14 September 2018

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Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?

14 September 2018

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A comprehensive review of interventions in the NOD mouse and implications for translation

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Clinical evidence for the safety of GAD65 immunomodulation in adult-onset autoimmune diabetes

14 September 2018

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Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

14 September 2018

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Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial--Type 1.

14 September 2018

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Peptide-based therapeutic vaccines for allergic and autoimmune diseases

14 September 2018

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T cell epitope immunotherapy induces a CD4+ T cell population with regulatory activity

14 September 2018

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Specific antigen vaccination to treat autoimmune disease

14 September 2018

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Preventing peptide-induced anaphylaxis: addition of C-terminal amino acids to produce a neutral isoelectric point

14 September 2018

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Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

14 September 2018

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Role of interleukin-10 in the induction and function of natural and antigen-induced regulatory T cells

14 September 2018

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Humoral and cellular immune responses to proinsulin in adults with newly diagnosed type 1 diabetes

14 September 2018

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Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23

14 September 2018

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Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus

14 September 2018

1 reference

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Effects of insulin in relatives of patients with type 1 diabetes mellitus

14 September 2018

1 reference

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Antigen-specific immunotherapy for autoimmune disease: fighting fire with fire?

14 September 2018

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Predominantly recognized proinsulin T helper cell epitopes in individuals with and without islet cell autoimmunity

14 September 2018

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Antibodies against homologous microbial caseinolytic proteases P characterise primary biliary cirrhosis

14 September 2018

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Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial

14 September 2018

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14 September 2018

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Association of interferon-gamma and interleukin 10 genotypes and serum levels with partial clinical remission in type 1 diabetes

14 September 2018

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12 December 2020

The 'dead in bed syndrome'- a cause of sudden death in Type 1 diabetes mellitus

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12 December 2020

Effect of T-cell peptides derived from Fel d 1 on allergic reactions and cytokine production in patients sensitive to cats: a randomised controlled trial

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12 December 2020

Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics

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12 December 2020

Limited duration of remission of insulin dependency in children with recent overt type I diabetes treated with low-dose cyclosporin

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12 December 2020

Immunomodulation in type 1 diabetes by NBI-6024, an altered peptide ligand of the insulin B epitope

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10.1111/J.1365-2249.2008.03814.X

Identifiers

DOI

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17 January 2020

PMC publication ID

2675245

0 references

1 reference

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