Self-inactivating gammaretroviral vectors for gene therapy of X-linked severe combined immunodeficiency. (Q40027548)

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scientific article published on 8 January 2008

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English	Self-inactivating gammaretroviral vectors for gene therapy of X-linked severe combined immunodeficiency.	scientific article published on 8 January 2008

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scholarly article

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Europe PubMed Central

PMC publication ID

6748866

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 December 2019

title

Self-inactivating gammaretroviral vectors for gene therapy of X-linked severe combined immunodeficiency (English)

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stated in

Europe PubMed Central

PMC publication ID

6748866

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

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31 December 2019

main subject

gene therapy

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severe combined immunodeficiency

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inferred from title

author

Neil J. Sebire

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8

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Europe PubMed Central

PMC publication ID

6748866

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

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31 December 2019

Adrian Thrasher

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12

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Europe PubMed Central

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6748866

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

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31 December 2019

author name string

Susannah I Thornhill

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1

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Europe PubMed Central

PMC publication ID

6748866

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

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31 December 2019

Steven J Howe

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3

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6748866

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

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31 December 2019

Meera Ulaganathan

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4

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PMC publication ID

6748866

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

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31 December 2019

Elke Grassman

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5

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6748866

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

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31 December 2019

David Williams

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6

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6748866

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

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31 December 2019

Bernhard Schiedlmeier

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7

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6748866

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31 December 2019

H Bobby Gaspar

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9

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6748866

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

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31 December 2019

Christine Kinnon

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10

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6748866

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31 December 2019

Christopher Baum

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11

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6748866

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

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31 December 2019

Axel Schambach

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2

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PMC publication ID

6748866

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

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31 December 2019

publication date

8 January 2008

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Europe PubMed Central

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6748866

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

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31 December 2019

published in

Molecular Therapy

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Europe PubMed Central

PMC publication ID

6748866

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

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31 December 2019

volume

16

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6748866

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31 December 2019

issue

3

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PMC publication ID

6748866

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

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31 December 2019

page(s)

590-598

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PMC publication ID

6748866

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31 December 2019

cites work

Hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency.

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Design of 5' untranslated sequences in retroviral vectors developed for medical use.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

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Restoration of lymphoid populations in a murine model of X-linked severe combined immunodeficiency by a gene-therapy approach

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

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Intrinsic defects of B cell function in X-linked severe combined immunodeficiency

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PubMed

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12 December 2020

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Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

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PubMed

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12 December 2020

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Plat-E: an efficient and stable system for transient packaging of retroviruses

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

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High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors

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12 December 2020

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Context Dependence of Different Modules for Posttranscriptional Enhancement of Gene Expression from Retroviral Vectors

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Lentivirus-mediated gene transfer in primary T cells is enhanced by a central DNA flap.

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12 December 2020

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Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

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High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

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Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

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Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

based on heuristic

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Gene therapy of X-linked severe combined immunodeficiency

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

based on heuristic

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Long-term survival and transplantation of haemopoietic stem cells for immunodeficiencies: report of the European experience 1968–99

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

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Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

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Self-inactivating retroviral vectors with improved RNA processing.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

based on heuristic

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Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

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Severe combined immunodeficiency. A model disease for molecular immunology and therapy

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

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Equal potency of gammaretroviral and lentiviral SIN vectors for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

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Woodchuck hepatitis virus post-transcriptional regulatory element deleted from X protein and promoter sequences enhances retroviral vector titer and expression

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

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Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overcoming promoter competition in packaging cells improves production of self-inactivating retroviral vectors

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lentiviral vectors containing an enhancer-less ubiquitously acting chromatin opening element (UCOE) provide highly reproducible and stable transgene expression in hematopoietic cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18180772

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18180772

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18180772

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation and analysis of interleukin-4 deficient mice

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel retroviral vectors for efficient expression of the multidrug resistance (mdr-1) gene in early hematopoietic cells.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the c-kit receptor in the adhesion of hematopoietic stem cells to stromal cells

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-frequency cell surface expression of a foreign protein in murine hematopoietic stem cells using a new retroviral vector.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Atypical X-Linked Severe Combined Immunodeficiency Due to Possible Spontaneous Reversion of the Genetic Defect in T Cells

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

based on heuristic

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Long-term immune reconstitution and outcome after HLA-nonidentical T-cell-depleted bone marrow transplantation for severe combined immunodeficiency: a European retrospective study of 116 patients.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18180772

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional role of interleukin-4 (IL-4) and IL-7 in the development of X-linked severe combined immunodeficiency

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18180772

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/SJ.MT.6300393

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stated in

Europe PubMed Central

PMC publication ID

6748866

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 December 2019

PMC publication ID

6748866

1 reference

stated in

Europe PubMed Central

PMC publication ID

6748866

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 December 2019

PubMed publication ID

18180772

1 reference

stated in

Europe PubMed Central

PMC publication ID

6748866

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18180772%20AND%20SRC:MED&resulttype=core&format=json

retrieved

31 December 2019

ResearchGate publication ID

5669114

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