SPECT imaging with 99mTc-labeled EGFR-specific nanobody for in vivo monitoring of EGFR expression (Q40009259)

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English	SPECT imaging with 99mTc-labeled EGFR-specific nanobody for in vivo monitoring of EGFR expression	scientific article

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PubMed publication ID

18297364

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16 September 2017

title

SPECT imaging with 99mTc-labeled EGFR-specific nanobody for in vivo monitoring of EGFR expression (English)

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PubMed publication ID

18297364

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16 September 2017

author name string

Lieven Huang

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1

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18297364

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16 September 2017

Lea Olive Tchouate Gainkam

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2

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18297364

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16 September 2017

Vicky Caveliers

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3

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18297364

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16 September 2017

Chris Vanhove

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4

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18297364

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16 September 2017

Marleen Keyaerts

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5

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18297364

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16 September 2017

Patrick De Baetselier

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6

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18297364

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16 September 2017

Axel Bossuyt

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7

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18297364

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16 September 2017

Hilde Revets

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8

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18297364

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16 September 2017

Tony Lahoutte

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9

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18297364

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16 September 2017

publication date

23 February 2008

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18297364

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16 September 2017

published in

Molecular Imaging and Biology

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18297364

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16 September 2017

volume

10

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18297364

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16 September 2017

issue

3

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18297364

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16 September 2017

page(s)

167-175

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18297364

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16 September 2017

cites work

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(89)Zr as a PET surrogate radioisotope for scouting biodistribution of the therapeutic radiometals (90)Y and (177)Lu in tumor-bearing nude mice after coupling to the internalizing antibody cetuximab.

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Re: controversies--[Tc(CO)3]+ chemistry: a promising new concept for SPET?

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The blood-brain barrier transmigrating single domain antibody: mechanisms of transport and antigenic epitopes in human brain endothelial cells

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Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing

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Tumor imaging using a picomolar affinity HER2 binding affibody molecule

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Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells.

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Expression and production of llama variable heavy-chain antibody fragments (V(HH)s) by Aspergillus awamori

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Affibody molecules: potential for in vivo imaging of molecular targets for cancer therapy

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Site-specifically conjugated anti-HER2 Affibody molecules as one-step reagents for target expression analyses on cells and xenograft samples

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An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability.

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12 December 2020

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Comparative biodistribution of potential anti-glioblastoma conjugates [111In]DTPA-hEGF and [111In]Bz-DTPA-hEGF in normal mice

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Efficient inhibition of EGFR signaling and of tumour growth by antagonistic anti-EFGR Nanobodies

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12 December 2020

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Synthetic affibody molecules: a novel class of affinity ligands for molecular imaging of HER2-expressing malignant tumors

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12 December 2020

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Radiolabeling and biological evaluation of DOTA-Ph-Al derivative conjugated to anti-EGFR antibody ior egf/r3 for targeted tumor imaging and therapy

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Targeting ErbB receptor signaling: a pan-ErbB approach to cancer

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12 December 2020

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Comparative properties of the single chain antibody and Fv derivatives of mAb 4-4-20. Relationship between interdomain interactions and the high affinity for fluorescein ligand

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Radioimmuno targetting (99m)technetium labeled anti-epidermal growth factor receptor monoclonal antibodies in experimental tumor models

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https://pubmed.ncbi.nlm.nih.gov/18297364

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12 December 2020

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Epidermal growth factor receptor in tumor angiogenesis

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EGFR function and detection in cancer therapy.

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Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry.

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12 December 2020

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EGFR and cancer prognosis

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Interest of the ordered subsets expectation maximization (OS-EM) algorithm in pinhole single-photon emission tomography reconstruction: a phantom study

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https://pubmed.ncbi.nlm.nih.gov/18297364

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Nanobodies as novel agents for cancer therapy

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Phase I/II clinical trial of the humanized anti-EGF-r monoclonal antibody h-R3 labelled with 99mTc in patients with tumour of epithelial origin

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12 December 2020

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The role of the epidermal growth factor receptor family in mammary tumorigenesis and metastasis

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111In-labeled EGF is selectively radiotoxic to human breast cancer cells overexpressing EGFR.

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12 December 2020

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[177Lu]Bz-DTPA-EGF: Preclinical characterization of a potential radionuclide targeting agent against glioma.

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Quantitative PET of EGFR expression in xenograft-bearing mice using 64Cu-labeled cetuximab, a chimeric anti-EGFR monoclonal antibody

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Functional heavy-chain antibodies in Camelidae

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Cetuximab and irinotecan as third-line therapy in advanced colorectal cancer patients: a single centre phase II trial

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Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme

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The pinhole: gateway to ultra-high-resolution three-dimensional radionuclide imaging

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Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431

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Signaling through the epidermal growth factor receptor during the development of malignancy

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AMIDE: a free software tool for multimodality medical image analysis

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12 December 2020

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Evaluation of radiolabeled ML04, a putative irreversible inhibitor of epidermal growth factor receptor, as a bioprobe for PET imaging of EGFR-overexpressing tumors

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12 December 2020

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Tailoring antibodies for radionuclide delivery

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12 December 2020

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Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer

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12 December 2020

based on heuristic

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Prostate-specific antigen immunosensing based on mixed self-assembled monolayers, camel antibodies and colloidal gold enhanced sandwich assays

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12 December 2020

based on heuristic

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Immunoscintigraphy with a technetium-99m labelled anti-epithelial growth factor receptor antibody in patients with non-small cell lung cancer

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18297364

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12 December 2020

based on heuristic

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Imaging of human tumor xenografts with an indium-111-labeled anti-epidermal growth factor receptor monoclonal antibody

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PubMed

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12 December 2020

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Distribution of humanized MAb 425 (EMD 62,000) in rats and specific localization in tumor-bearing nude mice

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https://pubmed.ncbi.nlm.nih.gov/18297364

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12 December 2020

based on heuristic

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Is there an immunohistochemical technique definitively valid in epidermal growth factor receptor assessment?

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18297364

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12 December 2020

based on heuristic

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Biodistribution of 99mTc-labeled anti-human epidermal growth factor receptor (EGF-R) humanized monoclonal antibody h-R3 in a xenograft model of human lung adenocarcinoma

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Production and response of a human prostatic cancer line to transforming growth factor-like molecules

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Diagnostic applications of radiolabeled peptides in nuclear endocrinology.

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12 December 2020

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A comparison of EGF and MAb 528 labeled with 111In for imaging human breast cancer

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18297364

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12 December 2020

based on heuristic

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In vivo study of a technetium labelled anti-EGFr MoAB

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https://pubmed.ncbi.nlm.nih.gov/18297364

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12 December 2020

based on heuristic

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Evidence for epidermal growth factor (EGF)-induced intermolecular autophosphorylation of the EGF receptors in living cells

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12 December 2020

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Naturally occurring antibodies devoid of light chains

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12 December 2020

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Assessing epidermal growth factor receptor expression in tumours: what is the value of current test methods?

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PubMed

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12 December 2020

based on heuristic

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In vivo evaluation of epidermal growth factor (EGF) receptor density on human tumor xenografts using radiolabeled EGF and anti-(EGF receptor) mAb 425

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12 December 2020

based on heuristic

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Isolation of antigen specific llama VHH antibody fragments and their high level secretion by Saccharomyces cerevisiae

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12 December 2020

based on heuristic

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Selection and identification of single domain antibody fragments from camel heavy-chain antibodies

1 reference

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12 December 2020

based on heuristic

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Immunohistochemical detection of EGFR in paraffin-embedded tumor tissues: variation in staining intensity due to choice of fixative and storage time of tissue sections

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12 December 2020

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Engineering and characterisation of chimeric monoclonal antibody 806 (ch806) for targeted immunotherapy of tumours expressing de2-7 EGFR or amplified EGFR

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https://pubmed.ncbi.nlm.nih.gov/18297364

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12 December 2020

based on heuristic

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Single antibody domains as small recognition units: design and in vitro antigen selection of camelized, human VH domains with improved protein stability

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12 December 2020

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Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies

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12 December 2020

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Camel heavy-chain antibodies: diverse germline V(H)H and specific mechanisms enlarge the antigen-binding repertoire

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12 December 2020

based on heuristic

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The influence of chelator on the pharmacokinetics of 99mTc-labelled peptides.

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12 December 2020

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Affibody-mediated tumour targeting of HER-2 expressing xenografts in mice.

1 reference

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12 December 2020

based on heuristic

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Technetium‐99m labeled epidermal growth factor‐tumor imaging in mice

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retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient tumor targeting by single-domain antibody fragments of camels

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https://pubmed.ncbi.nlm.nih.gov/18297364

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12 December 2020

based on heuristic

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Production and characterization of anti-(mucin MUC1) single-domain antibody in tobacco (Nicotiana tabacum cultivar Xanthi).

1 reference

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12 December 2020

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Assessment of epidermal growth factor receptor with 99mTc-ethylenedicysteine-C225 monoclonal antibody

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12 December 2020

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Identifiers

DOI

10.1007/S11307-008-0133-8

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Europe PubMed Central

PubMed publication ID

18297364

retrieved

16 September 2017

Dimensions Publication ID

1016741585

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PubMed publication ID

18297364

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18297364

retrieved

16 September 2017

ResearchGate publication ID

5555574

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