Succinic semialdehyde dehydrogenase deficiency, a disorder of GABA metabolism: an update on pharmacological and enzyme-replacement therapeutic strategies (Q49827097)

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scientific article published on 19 February 2018

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English	Succinic semialdehyde dehydrogenase deficiency, a disorder of GABA metabolism: an update on pharmacological and enzyme-replacement therapeutic strategies	scientific article published on 19 February 2018

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scholarly article

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Europe PubMed Central

PubMed publication ID

22 February 2018

http://europepmc.org/abstract/MED/29460030

Succinic semialdehyde dehydrogenase deficiency, a disorder of GABA metabolism: an update on pharmacological and enzyme-replacement therapeutic strategies (English)

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Europe PubMed Central

PubMed publication ID

22 February 2018

http://europepmc.org/abstract/MED/29460030

succinic semialdehyde dehydrogenase deficiency

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8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29460030%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Kara R Vogel

1

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4 June 2020

Garrett R Ainslie

2

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4 June 2020

Dana C Walters

3

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4 June 2020

Alice McConnell

4

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4 June 2020

Sameer C Dhamne

5

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4 June 2020

Alexander Rotenberg

6

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4 June 2020

Jean-Baptiste Roullet

7

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4 June 2020

publication date

19 February 2018

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Europe PubMed Central

PubMed publication ID

22 February 2018

http://europepmc.org/abstract/MED/29460030

Journal of Inherited Metabolic Disease

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4 June 2020

41

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4 June 2020

4

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4 June 2020

699-708

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4 June 2020

In vitro modeling of experimental succinic semialdehyde dehydrogenase deficiency (SSADHD) using brain-derived neural stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041169

26 August 2018

Toxicologic/transport properties of NCS-382, a γ-hydroxybutyrate (GHB) receptor ligand, in neuronal and epithelial cells: Therapeutic implications for SSADH deficiency, a GABA metabolic disorder

1 reference

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Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism

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Formulation and PEGylation optimization of the therapeutic PEGylated phenylalanine ammonia lyase for the treatment of phenylketonuria

1 reference

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26 August 2018

In vitro toxicological evaluation of NCS-382, a high-affinity antagonist of γ-hydroxybutyrate (GHB) binding

1 reference

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A pharmacokinetic evaluation and metabolite identification of the GHB receptor antagonist NCS-382 in mouse informs novel therapeutic strategies for the treatment of GHB intoxication

1 reference

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Aberrant mTOR signaling and disrupted autophagy: The missing link in potential vigabatrin-associated ocular toxicity?

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mTOR Inhibition Mitigates Molecular and Biochemical Alterations of Vigabatrin-Induced Visual Field Toxicity in Mice

1 reference

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26 August 2018

Therapeutic relevance of mTOR inhibition in murine succinate semialdehyde dehydrogenase deficiency (SSADHD), a disorder of GABA metabolism

1 reference

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Circadian dynamics in measures of cortical excitation and inhibition balance.

1 reference

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26 August 2018

mTOR inhibitors rescue premature lethality and attenuate dysregulation of GABAergic/glutamatergic transcription in murine succinate semialdehyde dehydrogenase deficiency (SSADHD), a disorder of GABA metabolism

1 reference

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Towards the development of an enzyme replacement therapy for the metabolic disorder propionic acidemia

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26 August 2018

Succinic semialdehyde dehydrogenase deficiency (SSADHD): Pathophysiological complexity and multifactorial trait associations in a rare monogenic disorder of GABA metabolism

1 reference

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26 August 2018

Torin 1 partially corrects vigabatrin-induced mitochondrial increase in mouse

1 reference

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26 August 2018

Defects in GABA metabolism affect selective autophagy pathways and are alleviated by mTOR inhibition

1 reference

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26 August 2018

GHB receptor targets in the CNS: focus on high-affinity binding sites

1 reference

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Acute Heart Failure Treatment

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New synthesis and tritium labeling of a selective ligand for studying high-affinity γ-hydroxybutyrate (GHB) binding sites.

1 reference

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Bumetanide enhances phenobarbital efficacy in a rat model of hypoxic neonatal seizures

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Development of the GABAergic System from Birth to Adolescence

1 reference

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26 August 2018

Succinic semialdehyde dehydrogenase deficiency: lessons from mice and men

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26 August 2018

Neurotransmitter alterations in embryonic succinate semialdehyde dehydrogenase (SSADH) deficiency suggest a heightened excitatory state during development

1 reference

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A ketogenic diet rescues the murine succinic semialdehyde dehydrogenase deficient phenotype

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1 reference

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Succinic semialdehyde dehydrogenase deficiency: GABAB receptor-mediated function

1 reference

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Status epilepticus in mice deficient for succinate semialdehyde dehydrogenase: GABAA receptor-mediated mechanisms

1 reference

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1 reference

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Absence seizures in succinic semialdehyde dehydrogenase deficient mice: a model of juvenile absence epilepsy.

1 reference

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26 August 2018

A review of pharmacology of NCS-382, a putative antagonist of gamma-hydroxybutyric acid (GHB) receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041169

26 August 2018

Selective gamma-hydroxybutyric acid receptor ligands increase extracellular glutamate in the hippocampus, but fail to activate G protein and to produce the sedative/hypnotic effect of gamma-hydroxybutyric acid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041169

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1 reference

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1 reference

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Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041169

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041169

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041169

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041169

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6041169

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4-Hydroxybutyric aciduria: application of a fluorometric assay to the determination of succinic semialdehyde dehydrogenase activity in extracts of cultured human lymphoblasts

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/29460030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seizure evolution and amino acid imbalances in murine succinate semialdehyde dehydrogenase (SSADH) deficiency

1 reference

9 November 2024

https://opencitations.net/index/api/v1/references/10.1007/S10545-018-0153-8

Altered cerebral glucose and acetate metabolism in succinic semialdehyde dehydrogenase-deficient mice: evidence for glial dysfunction and reduced glutamate/glutamine cycling

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Transcriptional regulation of dentin matrix protein 1 by JunB and p300 during osteoblast differentiation.

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9 November 2024

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10.1007/S10545-018-0153-8

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Europe PubMed Central

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4 June 2020

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4 June 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29460030%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

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