Differential role of the alpha1C subunit tails in regulation of the Cav1.2 channel by membrane potential, beta subunits, and Ca2+ ions (Q49112943)

18 February 2018

title

Differential role of the alpha1C subunit tails in regulation of the Cav1.2 channel by membrane potential, beta subunits, and Ca2+ ions (English)

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18 February 2018

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18 February 2018

Edward G. Lakatta

object named as

Edward Lakatta

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18 February 2018

Darrell Abernethy

object named as

Darrell R Abernethy

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18 February 2018

author name string

Evgeny Kobrinsky

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18 February 2018

Swasti Tiwari

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18 February 2018

Jo Beth Harry

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18 February 2018

Nikolai M Soldatov

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18 February 2018

language of work or name

English

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publication date

25 January 2005

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18 February 2018

Journal of Biological Chemistry

published in

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18 February 2018

volume

280

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18 February 2018

issue

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18 February 2018

page(s)

12474-12485

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18 February 2018

Calmodulin supports both inactivation and facilitation of L-type calcium channels.

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Modulation of Ca2+ signalling in rat atrial myocytes: possible role of the alpha1C carboxyl terminal

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Ca2+ channel moving tail: link between Ca2+-induced inactivation and Ca2+ signal transduction

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Dual function of the voltage-dependent Ca2+ channel alpha 2 delta subunit in current stimulation and subunit interaction.

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Inactivation of gating currents of L-type calcium channels. Specific role of the alpha 2 delta subunit

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Multiple modulation pathways of calcium channel activity by a beta subunit. Direct evidence of beta subunit participation in membrane trafficking of the alpha1C subunit

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Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells

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Cardiac L-type calcium channel beta-subunits expressed in human heart have differential effects on single channel characteristics

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Distinctive modulatory effects of five human auxiliary beta2 subunit splice variants on L-type calcium channel gating

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Molecular determinants of L-type Ca2+ channel inactivation. Segment exchange analysis of the carboxyl-terminal cytoplasmic motif encoded by exons 40-42 of the human alpha1C subunit gene

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New molecular determinant for inactivation of the human L-type alpha1C Ca2+ channel

21 January 2018

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Single-molecule imaging of l-type Ca(2+) channels in live cells

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New short splice variants of the human cardiac Cavbeta2 subunit: redefining the major functional motifs implemented in modulation of the Cav1.2 channel

21 January 2018

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Dual regulation of voltage-gated calcium channels by PtdIns(4,5)P2.

21 January 2018

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Akt-mediated cardiomyocyte survival pathways are compromised by G alpha q-induced phosphoinositide 4,5-bisphosphate depletion

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Feedback inhibition of Ca2+ channels by Ca2+ depends on a short sequence of the C terminus that does not include the Ca2+ -binding function of a motif with similarity to Ca2+ -binding domains

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Calcium channel beta subunit promotes voltage-dependent modulation of alpha 1 B by G beta gamma.

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Crucial role of N terminus in function of cardiac L-type Ca2+ channel and its modulation by protein kinase C.

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Endogenous Xenopus-oocyte Ca-channels are regulated by protein kinases A and C.

21 January 2018

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Evidence for the existence of RNA of Ca(2+)-channel alpha 2/delta subunit in Xenopus oocytes

21 January 2018

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The beta 1-subunit is essential for modulation by protein kinase C of an human and a non-human L-type Ca2+ channel

21 January 2018

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A Xenopus oocyte beta subunit: evidence for a role in the assembly/expression of voltage-gated calcium channels that is separate from its role as a regulatory subunit

21 January 2018

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21 January 2018

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Functional stoichiometry and local enrichment of calmodulin interacting with Ca2+ channels

21 January 2018

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Molecular architecture of the KvAP voltage-dependent K+ channel in a lipid bilayer

21 January 2018

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The I-II loop of the Ca2+ channel alpha1 subunit contains an endoplasmic reticulum retention signal antagonized by the beta subunit.

21 January 2018

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PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane

21 January 2018

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Monitoring Agonist-induced Phospholipase C Activation in Live Cells by Fluorescence Resonance Energy Transfer

21 January 2018

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Calcium channel β-subunit binds to a conserved motif in the I–II cytoplasmic linker of the α1-subunit

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M412140200

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18 February 2018

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18 February 2018