Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock (Q49092664)

18 February 2018

title

Simultaneous targeting of IL-1 and IL-18 is required for protection against inflammatory and septic shock (English)

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18 February 2018

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18 February 2018

Benjamin Vandendriessche

object named as

Benjamin Vandendriessche

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Peter Vandenabeele

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Dieter Demon

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18 February 2018

Pieter Bogaert

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18 February 2018

Alain Goethals

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18 February 2018

Bart Depuydt

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18 February 2018

Marnik Vuylsteke

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18 February 2018

Ria Roelandt

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18 February 2018

Elien Van Wonterghem

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18 February 2018

Jill Vandenbroecke

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18 February 2018

Sze Men Choi

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18 February 2018

Evelyn Meyer

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18 February 2018

Stefan Krautwald

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18 February 2018

Wim Declercq

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18 February 2018

Nozomi Takahashi

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18 February 2018

Anje Cauwels

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18 February 2018

language of work or name

English

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publication date

1 February 2014

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18 February 2018

American Journal of Respiratory and Critical Care Medicine

published in

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18 February 2018

volume

189

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18 February 2018

issue

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18 February 2018

page(s)

282-291

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18 February 2018

Immunotherapy for sepsis--a new approach against an ancient foe.

cites work

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Brief report: shock and multiple-organ dysfunction after self-administration of Salmonella endotoxin

21 January 2018

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

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Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling

21 January 2018

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Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

21 January 2018

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Cryopyrin activates the inflammasome in response to toxins and ATP

21 January 2018

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The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

21 January 2018

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Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

21 January 2018

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Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

21 January 2018

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Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production

21 January 2018

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Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme

21 January 2018

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Caspase-1-induced pyroptotic cell death

21 January 2018

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Inflammasomes as microbial sensors

21 January 2018

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The P2X(7) receptor-pannexin connection to dye uptake and IL-1beta release

21 January 2018

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The P2X7 receptor: a key player in IL-1 processing and release

21 January 2018

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Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor

21 January 2018

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Neutralization of IL-18 reduces neutrophil tissue accumulation and protects mice against lethal Escherichia coli and Salmonella typhimurium endotoxemia

21 January 2018

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Caspase-7 deficiency protects from endotoxin-induced lymphocyte apoptosis and improves survival.

21 January 2018

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Non-canonical inflammasome activation targets caspase-11

21 January 2018

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Interleukin-1 receptor blockade improves survival and hemodynamic performance in Escherichia coli septic shock, but fails to alter host responses to sublethal endotoxemia

21 January 2018

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Differential susceptibility to lethal endotoxaemia in mice deficient in IL-1α, IL-1β or IL-1 receptor type I.

21 January 2018

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Role of interleukin-18 (IL-18) during lethal shock: decreased lipopolysaccharide sensitivity but normal superantigen reaction in IL-18-deficient mice

21 January 2018

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Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia

21 January 2018

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Efficient gene modulation in mouse epiblast using a Sox2Cre transgenic mouse strain

21 January 2018

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Immunodesign of experimental sepsis by cecal ligation and puncture

21 January 2018

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RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome

21 January 2018

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Update on biologicals for treatment of juvenile idiopathic arthritis

21 January 2018

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Generation of neutralizing mouse anti-mouse IL-18 antibodies for inhibition of inflammatory responses in vivo

21 January 2018

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Endotoxins and other sepsis triggers

21 January 2018

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Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice

21 January 2018

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Caspase-1-mediated activation of interleukin-1beta (IL-1beta) and IL-18 contributes to innate immune defenses against Salmonella enterica serovar Typhimurium infection

21 January 2018

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Resistance to fever induction and impaired acute-phase response in interleukin-1 beta-deficient mice

21 January 2018

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Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice

21 January 2018

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An inactivating caspase-11 passenger mutation muddles sepsis research

21 January 2018

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An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1

21 January 2018

1 reference

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Pyroptosis: host cell death and inflammation

21 January 2018

1 reference

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Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes

21 January 2018

1 reference

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Cecal ligation and puncture: the gold standard model for polymicrobial sepsis?

21 January 2018

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Inflammasomes and their roles in health and disease

21 January 2018

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Caspase-11 protects against bacteria that escape the vacuole

21 January 2018

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Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock

21 January 2018

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Noncanonical inflammasome activation by intracellular LPS independent of TLR4.

21 January 2018

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https://api.crossref.org/works/10.1164%2FRCCM.201308-1535OC

A novel IL-18BP ELISA shows elevated serum IL-18BP in sepsis and extensive decrease of free IL-18.

21 January 2018

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Sepsis induced changes of adipokines and cytokines - septic patients compared to morbidly obese patients

21 January 2018

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Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. The Interleukin-1 Receptor Antagonist Sepsis Investigator Group

21 January 2018

1 reference

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Interleukin-18 and host defense against infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201308-1535OC

Interleukin-1 receptor antagonist reduces mortality from endotoxin shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201308-1535OC

10.1164/RCCM.201308-1535OC

21 January 2018

Identifiers

DOI

1 reference

18 February 2018

release_wwz7x6yg2fdrlgv5krnzcqa5fe

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/wwz7x6yg2fdrlgv5krnzcqa5fe

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

18 February 2018