Frequent allelic loss at 10q23 but low incidence of PTEN mutations in Merkel cell carcinoma. (Q49065989)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11291079%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Frequent allelic loss at 10q23 but low incidence of PTEN mutations in Merkel cell carcinoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11291079%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

main subject

Merkel cell carcinoma

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11291079%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

M Van Gele

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11291079%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

J H Leonard

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11291079%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

N Van Roy

1 reference

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6 November 2019

A De Paepe

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11291079%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

F Speleman

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6 November 2019

language of work or name

English

0 references

publication date

1 May 2001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11291079%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Cancer

6 November 2019

published in

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6 November 2019

volume

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6 November 2019

issue

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6 November 2019

page(s)

409-413

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The importance of postoperative radiation therapy in the treatment of Merkel cell carcinoma

6 November 2019

cites work

1 reference

Clinicopathologic correlations of cutaneous neuroendocrine Merkel cell carcinoma

21 January 2018

1 reference

Molecular analysis of 1p36 breakpoints in two Merkel cell carcinomas

21 January 2018

1 reference

Genetic changes associated with primary Merkel cell carcinoma

21 January 2018

1 reference

Small-cell lung cancer is characterized by a high incidence of deletions on chromosomes 3p, 4q, 5q, 10q, 13q and 17p

21 January 2018

1 reference

Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity

21 January 2018

1 reference

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

21 January 2018

1 reference

Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation

21 January 2018

1 reference

Characterization of cell lines established from Merkel-cell ("small-cell") carcinoma of the skin

21 January 2018

1 reference

Characterisation of four Merkel cell carcinoma adherent cell lines

21 January 2018

1 reference

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

1 reference

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

1 reference

Pten is essential for embryonic development and tumour suppression

21 January 2018

1 reference

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

1 reference

PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers

21 January 2018

1 reference

Mutation analysis of the PTEN/MMAC1 gene in lung cancer

21 January 2018

1 reference

Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

21 January 2018

1 reference

Epigenetic PTEN silencing in malignant melanomas without PTEN mutation

21 January 2018

1 reference

DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours

21 January 2018

1 reference

Mutation of the MXI1 gene in prostate cancer

21 January 2018

1 reference

A novel gene, LGI1, from 10q24 is rearranged and downregulated in malignant brain tumors

21 January 2018

1 reference

Identification of a human homolog of the Drosophila neuralized gene within the 10q25.1 malignant astrocytoma deletion region

21 January 2018

1 reference

Loss of heterozygosity of chromosome 10p in human gliomas.

21 January 2018

1 reference

Fine mapping of a region of common deletion on chromosome arm 10p in human glioma

21 January 2018

1 reference

Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignancy grades.

21 January 2018

1 reference

Structural and functional evidence for the presence of tumor suppressor genes on the short arm of chromosome 10 in human gliomas.

21 January 2018

1 reference

Loss of heterozygosity on chromosome 10 is more extensive in primary (de novo) than in secondary glioblastomas.

21 January 2018

1 reference

Loss of allelic heterozygosity on distal chromosome 1p in Merkel cell carcinoma

21 January 2018

1 reference

Loss of heterozygosity of chromosome 13 in Merkel cell carcinoma

21 January 2018

1 reference

PTEN germ-line mutations in juvenile polyposis coli

21 January 2018

1 reference

Multiple hamartoma syndrome (Cowden's disease) associated with renal cell carcinoma and primary neuroendocrine carcinoma of the skin (Merkel cell carcinoma)

21 January 2018

1 reference

Chromosomes 1, 11, and 13 are frequently involved in karyotypic abnormalities in metastatic Merkel cell carcinoma

21 January 2018

1 reference

Merkel cell carcinoma: in vitro and in vivo characteristics of a new cell line.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.1209

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11291079%20AND%20SRC:MED&resulttype=core&format=json

release_bax5moq6a5hp7hektrxj6qnaom

6 November 2019

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/bax5moq6a5hp7hektrxj6qnaom

mapped directly with Wikidata item

24 November 2022

based on heuristic

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11291079%20AND%20SRC:MED&resulttype=core&format=json