DJ-1 changes in G93A-SOD1 transgenic mice: implications for oxidative stress in ALS. (Q48961308)

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scientific article published on 19 August 2008

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English	DJ-1 changes in G93A-SOD1 transgenic mice: implications for oxidative stress in ALS.	scientific article published on 19 August 2008

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scholarly article

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Europe PubMed Central

PubMed publication ID

18712292

retrieved

17 February 2018

reference URL

http://europepmc.org/abstract/MED/18712292

title

DJ-1 changes in G93A-SOD1 transgenic mice: implications for oxidative stress in ALS. (English)

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Europe PubMed Central

PubMed publication ID

18712292

retrieved

17 February 2018

reference URL

http://europepmc.org/abstract/MED/18712292

main subject

amyotrophic lateral sclerosis

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author name string

Nirit Lev

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1

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Europe PubMed Central

PubMed publication ID

18712292

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17 February 2018

reference URL

http://europepmc.org/abstract/MED/18712292

Debby Ickowicz

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2

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Europe PubMed Central

PubMed publication ID

18712292

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17 February 2018

reference URL

http://europepmc.org/abstract/MED/18712292

Yael Barhum

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3

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Europe PubMed Central

PubMed publication ID

18712292

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17 February 2018

reference URL

http://europepmc.org/abstract/MED/18712292

Eldad Melamed

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4

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Europe PubMed Central

PubMed publication ID

18712292

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17 February 2018

reference URL

http://europepmc.org/abstract/MED/18712292

Daniel Offen

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5

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Europe PubMed Central

PubMed publication ID

18712292

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17 February 2018

reference URL

http://europepmc.org/abstract/MED/18712292

publication date

19 August 2008

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Europe PubMed Central

PubMed publication ID

18712292

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17 February 2018

reference URL

http://europepmc.org/abstract/MED/18712292

published in

Journal of Molecular Neuroscience

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Europe PubMed Central

PubMed publication ID

18712292

retrieved

17 February 2018

reference URL

http://europepmc.org/abstract/MED/18712292

volume

38

1 reference

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Europe PubMed Central

PubMed publication ID

18712292

retrieved

17 February 2018

reference URL

http://europepmc.org/abstract/MED/18712292

issue

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18712292

retrieved

17 February 2018

reference URL

http://europepmc.org/abstract/MED/18712292

page(s)

94-102

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Europe PubMed Central

PubMed publication ID

18712292

retrieved

17 February 2018

reference URL

http://europepmc.org/abstract/MED/18712292

cites work

Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target

1 reference

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Crossref

reference URL

https://api.crossref.org/works/10.1007%2FS12031-008-9138-7

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21 January 2018

Increased lipid peroxidation in sera of ALS patients: a potential biomarker of disease burden

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Crossref

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https://api.crossref.org/works/10.1007%2FS12031-008-9138-7

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21 January 2018

Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

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inferred from PubMed ID database lookup

On the relation of oxidative stress to neuroinflammation: lessons learned from the G93A-SOD1 mouse model of amyotrophic lateral sclerosis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18712292

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12 December 2020

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Relevance of oxidative injury in the pathogenesis of motor neuron diseases

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18712292

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12 December 2020

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inferred from PubMed ID database lookup

Remarkable increase in cerebrospinal fluid 3-nitrotyrosine in patients with sporadic amyotrophic lateral sclerosis

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/18712292

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

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12 December 2020

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inferred from PubMed ID database lookup

DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

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12 December 2020

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inferred from PubMed ID database lookup

Upregulation of protein-tyrosine nitration in the anterior horn cells of amyotrophic lateral sclerosis.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Oxidative damage to protein in sporadic motor neuron disease spinal cord

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein-bound crotonaldehyde accumulates in the spinal cord of superoxide dismutase-1 mutation-associated familial amyotrophic lateral sclerosis and its transgenic mouse model

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased oxidative damage to DNA in an animal model of amyotrophic lateral sclerosis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence of 4-hydroxynonenal in cerebrospinal fluid of patients with sporadic amyotrophic lateral sclerosis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The roles of free radicals in amyotrophic lateral sclerosis: reactive oxygen species and elevated oxidation of protein, DNA, and membrane phospholipids

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

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inferred from PubMed ID database lookup

The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

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12 December 2020

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inferred from PubMed ID database lookup

DJ-1 has a role in antioxidative stress to prevent cell death

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative insults induce DJ-1 upregulation and redistribution: implications for neuroprotection

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and metal content in blood and cerebrospinal fluid of amyotrophic lateral sclerosis patients with and without a Cu, Zn-superoxide dismutase mutation

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of Increased Oxidative Damage in Both Sporadic and Familial Amyotrophic Lateral Sclerosis

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of DJ-1 in the adult mouse CNS.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein oxidative damage in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for DNA damage in amyotrophic lateral sclerosis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased oxidative damage to DNA in ALS patients

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunocytochemical study on the distribution of nitrotyrosine in the brain of the transgenic mice expressing a human Cu/Zn SOD mutation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitration of manganese superoxide dismutase in cerebrospinal fluids is a marker for peroxynitrite-mediated oxidative stress in neurodegenerative diseases

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced oxygen radical production in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein nitration in a mouse model of familial amyotrophic lateral sclerosis: possible multifunctional role in the pathogenesis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and antioxidant enzyme upregulation in SOD1-G93A mouse skeletal muscle.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased 3‐nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DJ-1 mutations and parkinsonism-dementia-amyotrophic lateral sclerosis complex.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early activation of antioxidant mechanisms in muscle of mutant Cu/Zn-superoxide dismutase-linked amyotrophic lateral sclerosis mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DJ-1 interacts with HIPK1 and affects H2O2-induced cell death.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the Nrf2-ARE pathway in muscle and spinal cord during ALS-like pathology in mice expressing mutant SOD1.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship of oxygen radical-induced lipid peroxidative damage to disease onset and progression in a transgenic model of familial ALS.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18712292

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S12031-008-9138-7

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18712292

retrieved

17 February 2018

reference URL

http://europepmc.org/abstract/MED/18712292

PubMed publication ID

18712292

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18712292

retrieved

17 February 2018

reference URL

http://europepmc.org/abstract/MED/18712292

ResearchGate publication ID

23179582

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