Capture of somatic mtDNA point mutations with severe effects on oxidative phosphorylation in synaptosome cybrid clones from human brain. (Q48545022)

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16 February 2020

title

Capture of somatic mtDNA point mutations with severe effects on oxidative phosphorylation in synaptosome cybrid clones from human brain (English)

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16 February 2020

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16 February 2020

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16 February 2020

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16 February 2020

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16 February 2020

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16 February 2020

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16 February 2020

Maria Chiotis

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16 February 2020

Penny McKelvie

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16 February 2020

Richard G H Cotton

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16 February 2020

Michael Murphy

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16 February 2020

Justin C St John

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16 February 2020

publication date

1 December 2014

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16 February 2020

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16 February 2020

volume

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issue

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page(s)

1476-1484

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Sequence and organization of the human mitochondrial genome

16 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

The role of mitochondria in aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Somatic mitochondrial DNA mutations in single neurons and glia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Reactivity of cytosine and thymine in single-base-pair mismatches with hydroxylamine and osmium tetroxide and its application to the study of mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

A rapid Percoll gradient procedure for isolation of synaptosomes directly from an S1 fraction: homogeneity and morphology of subcellular fractions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

A mouse model of mitochondrial disease reveals germline selection against severe mtDNA mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

A mutation threshold distinguishes the antitumorigenic effects of the mitochondrial gene MTND1, an oncojanus function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Comparison of mitochondrial mutation spectra in ageing human colonic epithelium and disease: absence of evidence for purifying selection in somatic mitochondrial DNA point mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Mitochondrial DNA repair and association with aging--an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Microsatellite instability in the mitochondrial DNA of colorectal carcinomas: evidence for mismatch repair systems in mitochondrial genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

No recombination of mtDNA after heteroplasmy for 50 generations in the mouse maternal germline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Isolation of mitochondrial DNA-less mouse cell lines and their application for trapping mouse synaptosomal mitochondrial DNA with deletion mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Functional integrity of mitochondrial genomes in human platelets and autopsied brain tissues from elderly patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Making mitochondrial mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Human brain contains high levels of heteroplasmy in the noncoding regions of mitochondrial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Ultra-sensitive sequencing reveals an age-related increase in somatic mitochondrial mutations that are inconsistent with oxidative damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

The ageing mitochondrial genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Reactivity of potassium permanganate and tetraethylammonium chloride with mismatched bases and a simple mutation detection protocol

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Generation and bioenergetic analysis of cybrids containing mitochondrial DNA from mouse skeletal muscle during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Mitochondrial transformation: time for concerted action

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Mitochondrial protein synthesis: figuring the fundamentals, complexities and complications, of mammalian mitochondrial translation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Somatic mitochondrial DNA mutations in early Parkinson and incidental Lewy body disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Deciphering the signature of selective constraints on cancerous mitochondrial genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Chapter 18 Analysis of respiratory chain complex assembly with radiolabeled nuclear- and mitochondrial-encoded subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Nucleotide sequence preservation of human mitochondrial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Nucleotide sequence identity of mitochondrial DNA from different human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

HmtDB, a genomic resource for mitochondrion-based human variability studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Human mitochondrial DNA: roles of inherited and somatic mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

The reference human nuclear mitochondrial sequences compilation validated and implemented on the UCSC genome browser

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Mitochondrial DNA mutations in human colonic crypt stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Cytoplasmic transfer of the mtDNA nt 8993 T-->G (ATP6) point mutation associated with Leigh syndrome into mtDNA-less cells demonstrates cosegregation with a decrease in state III respiration and ADP/O ratio

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Cloning of neuronal mtDNA variants in cultured cells by synaptosome fusion with mtDNA-less cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Mitochondrial oxidative phosphorylation compensation may preserve vision in patients with OPA1-linked autosomal dominant optic atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

21 January 2018

Mitochondria and cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

The identification of mitochondrial DNA variants in glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694

Use of ethidium bromide to manipulate ratio of mutated and wild-type mitochondrial DNA in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22694