HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection (Q48471986)

11 February 2018

title

HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection (English)

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11 February 2018

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M Kaul

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11 February 2018

Q Ma

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11 February 2018

K E Medders

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11 February 2018

M K Desai

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11 February 2018

S A Lipton

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11 February 2018

publication date

14 July 2006

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11 February 2018

Cell Death & Differentiation

published in

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11 February 2018

volume

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11 February 2018

issue

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11 February 2018

page(s)

296-305

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11 February 2018

CD163 identifies a unique population of ramified microglia in HIV encephalitis (HIVE).

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CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

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Human immunodeficiency virus-associated dementia: an evolving disease

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Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis

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Caspase cascades in human immunodeficiency virus-associated neurodegeneration.

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Regulation of neural cell survival by HIV-1 infection.

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Genetic and functional analysis of full-length human immunodeficiency virus type 1 env genes derived from brain and blood of patients with AIDS.

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The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes

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Development of a human neuronal cell model for human immunodeficiency virus (HIV)-infected macrophage-induced neurotoxicity: apoptosis induced by HIV type 1 primary isolates and evidence for involvement of the Bcl-2/Bcl-xL-sensitive intrinsic apopto

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HIV associated neurodegeneration requires p53 in neurons and microglia

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The neuropathogenesis of AIDS

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Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity

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CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity

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Brain-derived neurotrophic factor inhibits human immunodeficiency virus-1/gp120-mediated cerebellar granule cell death by preventing gp120 internalization.

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Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

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Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

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7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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7 January 2021

Extracellular Signal-Regulated Kinase and p38 Subgroups of Mitogen-Activated Protein Kinases Regulate Inducible Nitric Oxide Synthase and Tumor Necrosis Factor-α Gene Expression in Endotoxin-Stimulated Primary Glial Cultures

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Beta-amyloid precursor protein transgenic mice that harbor diffuse A beta deposits but do not form plaques show increased ischemic vulnerability: role of inflammation

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7 January 2021

Human immunodeficiency virus (HIV)-induced neurotoxicity: roles for the NMDA receptor subtypes.

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7 January 2021

Acute neuroprotective synergy of erythropoietin and insulin-like growth factor I

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7 January 2021

CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor

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7 January 2021

Heterologous desensitization of T cell functions by CCR5 and CXCR4 ligands: inhibition of cellular signaling, adhesion and chemotaxis

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7 January 2021

Neuroprotective activity of chemokines against N-methyl-D-aspartate or beta-amyloid-induced toxicity in culture

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7 January 2021

Cerebrospinal fluid beta chemokine concentrations in neurocognitively impaired individuals infected with human immunodeficiency virus type 1.

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7 January 2021

Role for CCR5Delta32 protein in resistance to R5, R5X4, and X4 human immunodeficiency virus type 1 in primary CD4+ cells

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7 January 2021

Glutamate receptor signaling interplay modulates stress-sensitive mitogen-activated protein kinases and neuronal cell death

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7 January 2021

Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor

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7 January 2021

Chemokine receptors: signposts to brain development and disease

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7 January 2021

Glutamate neurotoxicity in cortical cell culture.

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7 January 2021

Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex

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7 January 2021

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

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7 January 2021

Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner

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7 January 2021

Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

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7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402006

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11 February 2018

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11 February 2018