Phosphatidylinositol phosphate kinase type 1gamma and beta1-integrin cytoplasmic domain bind to the same region in the talin FERM domain (Q48292433)

10 February 2018

title

Phosphatidylinositol phosphate kinase type 1gamma and beta1-integrin cytoplasmic domain bind to the same region in the talin FERM domain (English)

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10 February 2018

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10 February 2018

Gordon Roberts

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10 February 2018

Pietro De Camilli

object named as

Pietro De Camilli

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10 February 2018

Igor L Barsukov

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10 February 2018

Andrew Prescot

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10 February 2018

Neil Bate

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10 February 2018

Bipin Patel

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10 February 2018

David N Floyd

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10 February 2018

Nina Bhanji

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10 February 2018

Kresimir Letinic

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10 February 2018

Gilbert Di Paolo

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10 February 2018

David R Critchley

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10 February 2018

language of work or name

English

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publication date

2 June 2003

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10 February 2018

Journal of Biological Chemistry

published in

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10 February 2018

volume

278

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issue

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10 February 2018

page(s)

31202-31209

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10 February 2018

Integrins: bidirectional, allosteric signaling machines

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The phosphotyrosine binding-like domain of talin activates integrins

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Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration

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Dissecting the link between stress fibres and focal adhesions by CALI with EGFP fusion proteins.

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Integrins and actin filaments: reciprocal regulation of cell adhesion and signaling

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Bidirectional signaling between the cytoskeleton and integrins

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Integrin cytoplasmic domains mediate inside-out signal transduction

21 January 2018

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Disruption of the talin gene compromises focal adhesion assembly in undifferentiated but not differentiated embryonic stem cells

21 January 2018

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Analysis of the mammalian talin2 gene TLN2.

21 January 2018

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Disruption of the talin gene arrests mouse development at the gastrulation stage

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Talin is essential for integrin function in Drosophila

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Energy-filtered electron microscopy reveals that talin is a highly flexible protein composed of a series of globular domains.

21 January 2018

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Sequence and domain structure of talin

21 January 2018

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Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain

21 January 2018

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The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation

21 January 2018

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Integrin beta cytoplasmic domains differentially bind to cytoskeletal proteins.

21 January 2018

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Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain

21 January 2018

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Layilin, a novel talin-binding transmembrane protein homologous with C-type lectins, is localized in membrane ruffles

21 January 2018

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Localization of an integrin binding site to the C terminus of talin

21 January 2018

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Talin contains three similar vinculin-binding sites predicted to form an amphipathic helix

21 January 2018

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Structural determinants of integrin recognition by talin

21 January 2018

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Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin

21 January 2018

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Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

21 January 2018

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Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides

21 January 2018

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The relationship between force and focal complex development

21 January 2018

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Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate

21 January 2018

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Acidic phospholipids inhibit the intramolecular association between the N- and C-terminal regions of vinculin, exposing actin-binding and protein kinase C phosphorylation sites

21 January 2018

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Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown

21 January 2018

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Control of cellular phosphatidylinositol 4,5-bisphosphate levels by adhesion signals and rho GTPases in NIH 3T3 fibroblasts involvement of both phosphatidylinositol-4-phosphate 5-kinase and phospholipase C.

21 January 2018

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Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion

21 January 2018

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A method for efficient isotopic labeling of recombinant proteins

21 January 2018

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Resolution of conformational states of Dictyostelium myosin II motor domain using tryptophan (W501) mutants: implications for the open-closed transition identified by crystallography.

21 January 2018

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Effects of mutations in the cytoplasmic domain of integrin beta(1) to talin binding and cell spreading.

21 January 2018

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A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

21 January 2018

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Concerted activity of tyrosine phosphatase SHP-2 and focal adhesion kinase in regulation of cell motility

21 January 2018

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Cell Adhesion: A FERM Grasp of Membrane Dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303850200

Interaction of talin with actin: sensitive modulation of filament crosslinking activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303850200

Organization of the functional domains in membrane cytoskeletal protein talin

21 January 2018

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Functional genomic analysis reveals the utility of the I/LWEQ module as a predictor of protein:actin interaction

21 January 2018

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Identification of functional domains in the cytoskeletal protein talin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303850200

Peptide-specific antibodies localize the major lipid binding sites of talin dimers to oppositely arranged N-terminal 47 kDa subdomains

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M303850200

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10 February 2018

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10 February 2018