Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes (Q48286557)

10 February 2018

title

Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes (English)

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10 February 2018

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10 February 2018

David Allsop

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10 February 2018

author name string

Idira Obasse

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10 February 2018

Mark Taylor

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10 February 2018

publication date

20 October 2017

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10 February 2018

published in

Interface Focus

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10 February 2018

volume

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10 February 2018

issue

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10 February 2018

page(s)

20160127

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10 February 2018

Thioflavin T as an amyloid dye: fibril quantification, optimal concentration and effect on aggregation

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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Design of a mimic of nonamyloidogenic and bioactive human islet amyloid polypeptide (IAPP) as nanomolar affinity inhibitor of IAPP cytotoxic fibrillogenesis

5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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Integration of NMR and high-throughput screening

5 October 2018

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Principles of protein-protein interactions

5 October 2018

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5 October 2018

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Design of peptide-based inhibitors of human islet amyloid polypeptide fibrillogenesis

5 October 2018

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5 October 2018

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5 October 2018

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Inhibition of toxicity in the beta-amyloid peptide fragment beta -(25-35) using N-methylated derivatives: a general strategy to prevent amyloid formation

5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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5 October 2018

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The effect of single doses of pramlintide on gastric emptying of two meals in men with IDDM.

5 October 2018

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Pramlintide, a synthetic analog of human amylin, improves the metabolic profile of patients with type 2 diabetes using insulin. The Pramlintide in Type 2 Diabetes Group

5 October 2018

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Contribution of advanced glycosylation to the amyloidogenicity of islet amyloid polypeptide

5 October 2018

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5 October 2018

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Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

5 October 2018

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Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

5 October 2018

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Modulation of fibrillation of hIAPP core fragments by chemical modification of the peptide backbone

5 October 2018

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A preliminary electron microscopic investigation into the interaction between Aβ1-42 peptide and a novel nanoliposome- coupled retro-inverso peptide inhibitor, developed as a potential treatment for Alzheimer's disease

21 January 2018

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Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation

21 January 2018

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12 December 2020

Inhibition of hIAPP amyloid-fibril formation and apoptotic cell death by a designed hIAPP amyloid- core-containing hexapeptide

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12 December 2020

Amyloid Fibril Formation from Full-Length and Fragments of Amylin

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12 December 2020

Identification and characterization of a novel molecular-recognition and self-assembly domain within the islet amyloid polypeptide

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12 December 2020

A Single-Point Mutation Converts the Highly Amyloidogenic Human Islet Amyloid Polypeptide into a Potent Fibrillization Inhibitor

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12 December 2020

Exploring protein-ligand recognition with Binding MOAD

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12 December 2020

IAPP mimic blocks Abeta cytotoxic self-assembly: cross-suppression of amyloid toxicity of Abeta and IAPP suggests a molecular link between Alzheimer's disease and type II diabetes

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12 December 2020

Identifiers

DOI

10.1098/RSFS.2016.0127

1 reference

10 February 2018

PMC publication ID

5665791

0 references

1 reference

10 February 2018