The ATM protein is required for sustained activation of NF-kappaB following DNA damage (Q48211878)

9 February 2018

title

The ATM protein is required for sustained activation of NF-kappaB following DNA damage (English)

1 reference

9 February 2018

0 references

B Piret

1 reference

9 February 2018

S Schoonbroodt

series ordinal

1 reference

9 February 2018

J Piette

series ordinal

1 reference

9 February 2018

language of work or name

English

0 references

publication date

1 April 1999

1 reference

9 February 2018

published in

Oncogene

1 reference

9 February 2018

volume

1 reference

9 February 2018

issue

1 reference

9 February 2018

page(s)

2261-2271

1 reference

9 February 2018

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

1 reference

Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Separation of oxidant-initiated and redox-regulated steps in the NF-kappa B signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

The NF-kappa B and I kappa B proteins: new discoveries and insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

The DNA-dependent protein kinase participates in the activation of NF kappa B following DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Sequential DNA damage-independent and -dependent activation of NF-kappaB by UV

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

DNA strand breaks produced by oxidative stress in mammalian cells exhibit 3'-phosphoglycolate termini.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Ionizing radiation induces expression and binding activity of the nuclear factor kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

NF-kappa B activation by ultraviolet light not dependent on a nuclear signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Redox regulation of NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Overexpression of a truncated human topoisomerase III partially corrects multiple aspects of the ataxia-telangiectasia phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Topoisomerase Poisons: Harnessing the Dark Side of Enzyme Mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Induction of the WAF1/CIP1 protein and apoptosis in human T-cell leukemia virus type I-transformed lymphocytes after treatment with adriamycin by using a p53-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Predominance of null mutations in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Telomeres shorten during ageing of human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Domain organization of I kappa B alpha and sites of interaction with NF-kappa B p65.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Correction of radiation sensitivity in ataxia telangiectasia cells by a truncated I kappa B-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Functional interaction between DNA-PK and c-Abl in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

The genetic defect in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

The DNA-dependent protein kinase, DNA-PK: 10 years and no ends in sight

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

DNA-dependent protein kinase phosphorylation of IkappaB alpha and IkappaB beta regulates NF-kappaB DNA binding properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Eukaryotic DNA topoisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Three distinct signalling responses by murine fibroblasts to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Signal transduction through NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Accelerated telomere shortening in ataxia telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

High-frequency transformation of human repair-deficient cell lines by an Epstein-Barr virus-based cDNA expression vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

NF-kappa B transcription factor and human immunodeficiency virus type 1 (HIV-1) activation by methylene blue photosensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Topoisomerase poisons activate the transcription factor NF-kappaB in ACH-2 and CEM cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Induction of p21 mediated by reactive oxygen species formed during the metabolism of aziridinylbenzoquinones by HCT116 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Topoisomerase I inhibitors: Review and update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

The nuclear tyrosine kinase c-Abl negatively regulates cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Interaction between ATM protein and c-Abl in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Protein-tyrosine phosphatase inhibitors block tumor necrosis factor-dependent activation of the nuclear transcription factor NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Free radicals and anticancer drug resistance: oxygen free radicals in the mechanisms of drug cytotoxicity and resistance by certain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Inhibition of apoptosis by antioxidants in the human HL-60 leukemia cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

DNA-dependent protein kinase acts upstream of p53 in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Reduced telomere length in ataxia-telangiectasia fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Requirements for p53 and the ATM gene product in the regulation of G1/S and S phase checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Dual roles of ATM in the cellular response to radiation and in cell growth control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

Recombinant ATM protein complements the cellular A-T phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

21 January 2018

A sense-abl response?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

IkappaB alpha overexpression in human breast carcinoma MCF7 cells inhibits nuclear factor-kappaB activation but not tumor necrosis factor-alpha-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

7 January 2021

Yeast Ku as a regulator of chromosomal DNA end structure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

7 January 2021

Reactive oxygen intermediates are involved in the induction of CD95 ligand mRNA expression by cytostatic drugs in hepatoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

7 January 2021

Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

7 January 2021

Genetic complementation analysis of ataxia telangiectasia and Nijmegen breakage syndrome: a survey of 50 patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

7 January 2021

Transcription factor NF-kappa B is activated by photosensitization generating oxidative DNA damages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

7 January 2021

Inhibitors of ADP-ribosylation impair inducible nitric oxide synthase gene transcription through inhibition of NF kappa B activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

7 January 2021

A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

7 January 2021

Damage to DNA by UV light and activation of transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

7 January 2021

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

7 January 2021

Antioxidant and redox regulation of gene transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

7 January 2021

Influence of ATM function on telomere metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202541

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202541

1 reference

9 February 2018

1 reference

9 February 2018