Interferon lambda1/IL-29 and inorganic polyphosphate are novel regulators of neutrophil-driven thromboinflammation. (Q48175284)

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24 March 2020

title

Interferon lambda1/IL-29 and inorganic polyphosphate are novel regulators of neutrophil-driven thromboinflammation (English)

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24 March 2020

author name string

Akrivi Chrysanthopoulou

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24 March 2020

Konstantinos Kambas

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24 March 2020

Dimitrios Stakos

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24 March 2020

Ioannis Mitroulis

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24 March 2020

Alexandros Mitsios

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24 March 2020

Veroniki Vidali

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Iliana Angelidou

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24 March 2020

Magdalena Bochenek

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24 March 2020

Stella Arelaki

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24 March 2020

Athanasios Arampatzioglou

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Ioanna-Evdokia Galani

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Panagiotis Skendros

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Elias A Couladouros

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Stavros Konstantinides

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Evangelos Andreakos

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publication date

7 August 2017

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volume

243

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issue

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page(s)

111-122

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Thrombosis: a major contributor to global disease burden.

24 March 2020

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Inorganic polyphosphate in the origin and survival of species

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Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo

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Human platelet dense granules contain polyphosphate and are similar to acidocalcisomes of bacteria and unicellular eukaryotes.

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Polyphosphate is a cofactor for the activation of factor XI by thrombin

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Polyphosphate modifies the fibrin network and down-regulates fibrinolysis by attenuating binding of tPA and plasminogen to fibrin.

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Resolving Thromboinflammation in the Brain After Ischemic Stroke?

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Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation

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Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases.

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Netting neutrophils in autoimmune small-vessel vasculitis

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C5a and TNF-alpha up-regulate the expression of tissue factor in intra-alveolar neutrophils of patients with the acute respiratory distress syndrome

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Myeloma cells contain high levels of inorganic polyphosphate which is associated with nucleolar transcription

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21 January 2018

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Regulation of the autophagic machinery in human neutrophils

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21 January 2018

Identifiers

DOI

10.1002/PATH.4935

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Fatcat ID

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24 November 2022

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