High nigral iron deposition in LRRK2 and Parkin mutation carriers using R2* relaxometry (Q48159358)

9 February 2018

title

High nigral iron deposition in LRRK2 and Parkin mutation carriers using R2* relaxometry (English)

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9 February 2018

author

Jean-Christophe Corvol

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Hartwig R. Siebner

object named as

Hartwig Siebner

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Marie Vidailhet

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Nadya Pyatigorskaya

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9 February 2018

Michael Sharman

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Romain Valabregue

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Lydia Yahia-Cherif

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Fabrice Poupon

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Florence Cormier-Dequaire

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Stephan Klebe

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Alexis Brice

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Stephane Lehéricy

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9 February 2018

language of work or name

English

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publication date

22 May 2015

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9 February 2018

published in

Movement Disorders

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volume

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issue

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page(s)

1077-1084

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Role of mendelian genes in "sporadic" Parkinson's disease

cites work

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LRRK2 G2019S in families with Parkinson disease who originated from Europe and the Middle East: evidence of two distinct founding events beginning two millennia ago.

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Low disease risk in relatives of north african lrrk2 Parkinson disease patients

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Association between early-onset Parkinson's disease and mutations in the parkin gene

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Advances in the genetics of Parkinson disease

21 January 2018

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Assessment of relative brain iron concentrations using T2-weighted and T2*-weighted MRI at 3 Tesla.

21 January 2018

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Imaging iron stores in the brain using magnetic resonance imaging

21 January 2018

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High resolution magnetic susceptibility mapping of the substantia nigra in Parkinson's disease

21 January 2018

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Correlation of R2 with total iron concentration in the brains of rhesus monkeys.

21 January 2018

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Brain iron deposition in Parkinson's disease imaged using the PRIME magnetic resonance sequence.

21 January 2018

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Quantitative mapping of T1 and T2* discloses nigral and brainstem pathology in early Parkinson's disease

21 January 2018

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Combined R2* and diffusion tensor imaging changes in the substantia nigra in Parkinson's disease

21 January 2018

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Imaging the impact of genes on Parkinson's disease

21 January 2018

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Clinical and brain imaging characteristics in leucine-rich repeat kinase 2-associated PD and asymptomatic mutation carriers

21 January 2018

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Echogenicity of the substantia nigra: association with increased iron content and marker for susceptibility to nigrostriatal injury

21 January 2018

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Substantia nigra hyperechogenicity with LRRK2 G2019S mutations

21 January 2018

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21 January 2018

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7 Tesla magnetic resonance imaging: a closer look at substantia nigra anatomy in Parkinson's disease

21 January 2018

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Is R2* a new MRI biomarker for the progression of Parkinson's disease? A longitudinal follow-up

21 January 2018

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Substantia nigra hyperechogenicity correlates with clinical status and number of Parkin mutated alleles.

21 January 2018

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Brain parenchyma sonography detects preclinical parkinsonism.

21 January 2018

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Transcranial ultrasound in different monogenetic subtypes of Parkinson's disease

21 January 2018

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Morphometric fingerprint of asymptomatic Parkin and PINK1 mutation carriers in the basal ganglia.

21 January 2018

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Deciphering the role of heterozygous mutations in genes associated with parkinsonism

21 January 2018

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Structural findings in the basal ganglia in genetically determined and idiopathic Parkinson's disease

21 January 2018

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Quantitative MR imaging of brain iron: a postmortem validation study

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/MDS.26218

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9 February 2018

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9 February 2018