IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture (Q48158969)

10 June 2018

title

IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture (English)

1 reference

10 June 2018

Tetratricopeptide repeat domain 26

main subject

1 reference

GOA release 2020-03-11

1 reference

PubMed publication ID

28264835

9 February 2018

http://europepmc.org/abstract/MED/28264835

author name string

Daisy Xin

1 reference

10 June 2018

Kasey J Christopher

1 reference

10 June 2018

Lewie Zeng

1 reference

10 June 2018

Yong Kong

1 reference

10 June 2018

language of work or name

English

0 references

publication date

6 March 2017

1 reference

10 June 2018

number of pages

1 reference

based on heuristic

inferred from page(s)

published in

Development

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10 June 2018

volume

144

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10 June 2018

issue

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10 June 2018

page(s)

1544-1553

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10 June 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5399663/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex

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IFT46 plays an essential role in cilia development

14 June 2018

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IFT27 links the BBSome to IFT for maintenance of the ciliary signaling compartment.

14 June 2018

1 reference

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The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.

14 June 2018

1 reference

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A mutation in the mouse ttc26 gene leads to impaired hedgehog signaling

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Switching on cilia: transcriptional networks regulating ciliogenesis

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TTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagella

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14 June 2018

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Limb anterior-posterior polarity integrates activator and repressor functions of GLI2 as well as GLI3

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Knockdown of ttc26 disrupts ciliogenesis of the photoreceptor cells and the pronephros in zebrafish

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Forward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling

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Mutations in Traf3ip1 reveal defects in ciliogenesis, embryonic development, and altered cell size regulation

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14 June 2018

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The Type 3 Adenylyl Cyclase Is Required for Novel Object Learning and Extinction of Contextual Memory: Role of cAMP Signaling in Primary Cilia

14 June 2018

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Human and mouse mutations in WDR35 cause short-rib polydactyly syndromes due to abnormal ciliogenesis

14 June 2018

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Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components

14 June 2018

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Biochemical analysis of PIFTC3, the Trypanosoma brucei orthologue of nematode DYF‐13, reveals interactions with established and putative intraflagellar transport components

14 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

The primary cilium: a signalling centre during vertebrate development

14 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Centrioles, centrosomes, and cilia in health and disease

14 June 2018

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Genetic diagnosis by whole exome capture and massively parallel DNA sequencing

14 June 2018

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A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling

14 June 2018

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Adenylate cyclase regulates elongation of mammalian primary cilia

14 June 2018

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14 June 2018

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14 June 2018

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The primary cilium as a cellular signaling center: lessons from disease

14 June 2018

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Characterization of mouse IFT complex B

14 June 2018

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Ciliary dysfunction in developmental abnormalities and diseases

14 June 2018

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Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb

14 June 2018

1 reference

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Canine polydactyl mutations with heterogeneous origin in the conserved intronic sequence of LMBR1

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

When cilia go bad: cilia defects and ciliopathies

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Patched1 regulates hedgehog signaling at the primary cilium

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

The graded response to Sonic Hedgehog depends on cilia architecture

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

The Shh-independent activator function of the full-length Gli3 protein and its role in vertebrate limb digit patterning

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Hippi is essential for node cilia assembly and Sonic hedgehog signaling

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

The Ciliopathies: An Emerging Class of Human Genetic Disorders

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Functional genomics of the cilium, a sensory organelle

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Hedgehog signalling in the mouse requires intraflagellar transport proteins

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

14 June 2018

Intraflagellar transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Identification and characterization of polycystin-2, the PKD2 gene product

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Graded sonic hedgehog signaling and the specification of cell fate in the ventral neural tube

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Chlamydomonas kinesin-II-dependent intraflagellar transport (IFT): IFT particles contain proteins required for ciliary assembly in Caenorhabditis elegans sensory neurons

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT)

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

The Chlamydomonas kinesin-like protein FLA10 is involved in motility associated with the flagellar membrane

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

A motility in the eukaryotic flagellum unrelated to flagellar beating

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Hop-sterile, a mutant gene affecting sperm tail development in the mouse

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Intraflagellar transport proteins 172, 80, 57, 54, 38, and 20 form a stable tubulin-binding IFT-B2 complex

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Assembly of primary cilia

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Intraflagellar transport: from molecular characterisation to mechanism

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Btrim: A fast, lightweight adapter and quality trimming program for next-generation sequencing technologies

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Triphalangeal thumb-polysyndactyly syndrome and syndactyly type IV are caused by genomic duplications involving the long range, limb-specific SHH enhancer.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Two novel point mutations in the long-range SHH enhancer in three families with triphalangeal thumb and preaxial polydactyly

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Progression of vertebrate limb development through SHH-mediated counteraction of GLI3.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

Identification of sonic hedgehog as a candidate gene responsible for the polydactylous mouse mutant Sasquatch.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399663

14 August 2018

Identifiers

DOI

10.1242/DEV.143255

1 reference

10 June 2018

PMC publication ID

5399663

1 reference

10 June 2018

PubMed publication ID

28264835

1 reference

10 June 2018