Loss of TGF-beta 1 leads to increased neuronal cell death and microgliosis in mouse brain (Q48110101)

8 February 2018

title

Loss of TGF-beta 1 leads to increased neuronal cell death and microgliosis in mouse brain (English)

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8 February 2018

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Eliezer Masliah

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8 February 2018

Tony Wyss-Coray

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8 February 2018

author name string

Thomas C Brionne

series ordinal

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8 February 2018

Ina Tesseur

series ordinal

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8 February 2018

language of work or name

English

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publication date

1 December 2003

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8 February 2018

published in

Neuron

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8 February 2018

volume

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8 February 2018

issue

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8 February 2018

page(s)

1133-1145

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8 February 2018

TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death.

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Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype

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Laminin chain expression suggests that laminin-10 is a major isoform in the mouse hippocampus and is degraded by the tissue plasminogen activator/plasmin protease cascade during excitotoxic injury

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Short communication: transforming growth factor-beta mediates the neurotrophic effect of fibroblast growth factor-2 on midbrain dopaminergic neurons

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Reduction of endogenous transforming growth factors beta prevents ontogenetic neuron death

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7 January 2021

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

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Murine models define the role of TGF-beta as a master regulator of immune cell function

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Endocrine expression of the active form of TGF-beta1 in the TGF-beta1 null mice fails to ameliorate lethal phenotype

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7 January 2021

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7 January 2021

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7 January 2021

Transforming growth factor beta: a matter of life and death

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7 January 2021

Bone morphogenetic proteins in the nervous system

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7 January 2021

TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Glial cell line-derived neurotrophic factor rescues target-deprived sympathetic spinal cord neurons but requires transforming growth factor-beta as cofactor in vivo.

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7 January 2021

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

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7 January 2021

Transforming growth factor-beta1 enhances expression of brain-derived neurotrophic factor and its receptor, TrkB, in neurons cultured from rat cerebral cortex

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7 January 2021

Unrestricted synaptic growth in spinster-a late endosomal protein implicated in TGF-beta-mediated synaptic growth regulation.

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7 January 2021

Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

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7 January 2021

Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord

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7 January 2021

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7 January 2021

Co-activation of TGF-ss and cytokine signaling pathways are required for neurotrophic functions

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7 January 2021

TGF-betas and their roles in the regulation of neuron survival

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7 January 2021

Extracellular matrix. 2: Role of extracellular matrix molecules and their receptors in the nervous system.

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7 January 2021

Functions of mammalian Smad genes as revealed by targeted gene disruption in mice

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7 January 2021

Chronic overproduction of transforming growth factor-beta1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice

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7 January 2021

TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

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7 January 2021

Cortical degeneration in the absence of neurotrophin signaling: dendritic retraction and neuronal loss after removal of the receptor TrkB.

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7 January 2021

Role of transforming growth factor-beta in long-term synaptic facilitation in Aplysia

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7 January 2021

TGF-beta signaling activates steroid hormone receptor expression during neuronal remodeling in the Drosophila brain

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7 January 2021

10.1016/S0896-6273(03)00766-9

Identifiers

DOI

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8 February 2018

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8 February 2018