Prion-like transmission of α-synuclein pathology in the context of an NFL null background (Q48090188)

8 February 2018

title

Prion-like transmission of α-synuclein pathology in the context of an NFL null background (English)

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8 February 2018

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Nicola J Rutherford

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8 February 2018

Mieu Brooks

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8 February 2018

Cara J Riffe

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8 February 2018

Kimberly-Marie M Gorion

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8 February 2018

Jasie K Howard

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8 February 2018

Jess-Karan S Dhillon

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8 February 2018

Benoit I Giasson

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8 February 2018

language of work or name

English

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publication date

27 September 2017

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8 February 2018

number of pages

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inferred from page(s)

published in

Neuroscience Letters

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8 February 2018

volume

661

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8 February 2018

page(s)

114-120

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8 February 2018

Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease

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Robust Central Nervous System Pathology in Transgenic Mice following Peripheral Injection of α-Synuclein Fibrils

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Novel antibodies to phosphorylated α-synuclein serine 129 and NFL serine 473 demonstrate the close molecular homology of these epitopes

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Intramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic mice.

29 September 2018

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Amyloidogenic α-synuclein seeds do not invariably induce rapid, widespread pathology in mice

29 September 2018

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100 years of Lewy pathology

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Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

29 September 2018

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29 September 2018

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Heterogeneous inclusions in neurofilament inclusion disease

29 September 2018

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The biochemistry of Parkinson's disease

29 September 2018

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Extending the clinicopathological spectrum of neurofilament inclusion disease

29 September 2018

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The E46K mutation in alpha-synuclein increases amyloid fibril formation.

29 September 2018

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Analysis of heavy neurofilament subunit gene polymorphism in Russian patients with sporadic motor neuron disease (MND).

29 September 2018

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Temporal lobe pathology of human patients with neurofilament inclusion disease

29 September 2018

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Functions of intermediate filaments in neuronal development and disease

29 September 2018

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A comparison of amyloid fibrillogenesis using the novel fluorescent compound K114.

29 September 2018

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Neurofilament inclusion body disease: a new proteinopathy?

29 September 2018

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Mutations in the neurofilament light chain gene (NEFL) cause early onset severe Charcot-Marie-Tooth disease.

29 September 2018

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Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein

29 September 2018

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Attenuated neurodegenerative disease phenotype in tau transgenic mouse lacking neurofilaments

29 September 2018

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Further evidence that neurofilament light chain gene mutations can cause Charcot-Marie-Tooth disease type 2E.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813496

A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813496

A new variant of Charcot-Marie-Tooth disease type 2 is probably the result of a mutation in the neurofilament-light gene

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813496

Delayed maturation of regenerating myelinated axons in mice lacking neurofilaments

29 September 2018

1 reference

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Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins

29 September 2018

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Neurofilament deficiency in quail caused by nonsense mutation in neurofilament-L gene

29 September 2018

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Neurofilaments are obligate heteropolymers in vivo

29 September 2018

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Assembly of type IV neuronal intermediate filaments in nonneuronal cells in the absence of preexisting cytoplasmic intermediate filaments

29 September 2018

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Infantile neuroaxonal dystrophy--immunohistochemical and ultrastructural studies on the central and peripheral nervous systems in infantile neuroaxonal dystrophy

29 September 2018

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Neuroaxonal dystrophy in HTLV-1-associated myelopathy/tropical spastic paraparesis: neuropathologic and neuroimmunologic correlations

29 September 2018

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Immunohistochemical localization of neurofilament protein in neuronal degenerations.

29 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813496

Lewy Bodies of Parkinson's Disease Contain Neurofilament Antigens

29 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813496

Neurofilament gene expression: a major determinant of axonal caliber

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813496

Lewy bodies contain epitopes both shared and distinct from Alzheimer neurofibrillary tangles.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813496

Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813496

Two monoclonal antibodies recognize Alzheimer's neurofibrillary tangles, neurofilament, and microtubule-associated proteins.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813496

Reaction of Lewy bodies with antibodies to phosphorylated and non-phosphorylated neurofilaments

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813496

Relative abundance of tau and neurofilament epitopes in hippocampal neurofibrillary tangles

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5813496

Neurofilament inclusion body disease with early onset frontotemporal dementia and primary lateral sclerosis

29 September 2018

1 reference

12 December 2020

1 reference

12 December 2020

Neurofilaments in health and disease

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12 December 2020

Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform

1 reference

12 December 2020

A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease

1 reference

12 December 2020

Neuropathologic and morphometric studies in hereditary motor and sensory neuropathy type II with neurofilament accumulation

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12 December 2020

Peripherin and neurofilament protein coexist in spinal spheroids of motor neuron disease

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12 December 2020

Hereditary hypotrophic axonopathy with neurofilament deficiency in a mutant strain of the Japanese quail

1 reference

12 December 2020

Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis

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12 December 2020

Reduced diameter and conduction velocity of myelinated fibers in the sciatic nerve of a neurofilament-deficient mutant quail

1 reference

12 December 2020

10.1016/J.NEULET.2017.09.054

Identifiers

DOI

1 reference

8 February 2018

PMC publication ID

5813496

0 references

1 reference

8 February 2018