Ranolazine improves diastolic function in spontaneously hypertensive rats (Q47919972)

6 February 2018

title

Ranolazine improves diastolic function in spontaneously hypertensive rats (English)

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6 February 2018

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Sarah Williams

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6 February 2018

Marc Pourrier

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6 February 2018

Donald McAfee

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6 February 2018

Shunping Lin

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6 February 2018

David Fedida

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6 February 2018

publication date

24 January 2014

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6 February 2018

American Journal of Physiology Heart and Circulatory Physiology

published in

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6 February 2018

volume

306

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6 February 2018

issue

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6 February 2018

page(s)

H867-81

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6 February 2018

Inhibition of the late sodium current slows t-tubule disruption during the progression of hypertensive heart disease in the rat.

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Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties

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Inhibition of the late sodium current as a potential cardioprotective principle: effects of the late sodium current inhibitor ranolazine

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Heart Failure with Preserved Ejection Fraction: Persistent Diagnosis, Therapeutic Enigma

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Diastolic and systolic heart failure are distinct phenotypes within the heart failure spectrum

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Effect of loading conditions, contractile state, and heart rate on early diastolic left ventricular filling in conscious dogs

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Reduction of cardiac fibrosis decreases systolic performance without affecting diastolic function in hypertensive rats.

21 January 2018

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Effect of tetrodotoxin on action potentials of the conducting system in the dog heart

21 January 2018

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Intracellular Na(+) concentration is elevated in heart failure but Na/K pump function is unchanged

21 January 2018

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Ranolazine, an antianginal agent, markedly reduces ventricular arrhythmias induced by ischemia and ischemia-reperfusion

21 January 2018

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The onset of left ventricular diastolic dysfunction in SHR rats is not related to hypertrophy or hypertension

21 January 2018

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The effects of halothane and isoflurane on slowly inactivating sodium current in canine cardiac Purkinje cells

21 January 2018

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Ranolazine for the Treatment of Heart Failure With Preserved Ejection Fraction: Background, Aims, and Design of the RALI‐DHF Study

21 January 2018

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Nuclear magnetic resonance measurement of intracellular sodium in the perfused normotensive and spontaneously hypertensive rat heart

21 January 2018

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Evidence that ranolazine behaves as a weak beta1- and beta2-adrenoceptor antagonist in the rat [correction of cat] cardiovascular system

21 January 2018

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Ranolazine improves cardiac diastolic dysfunction through modulation of myofilament calcium sensitivity

21 January 2018

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New treatment options for late Na current, arrhythmias, and diastolic dysfunction

21 January 2018

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Assessment of left ventricular relaxation by Doppler echocardiography. Comparison of isovolumic relaxation time and transmitral flow velocities with time constant of isovolumic relaxation.

21 January 2018

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Loss of adrenergic augmentation of diastolic intra-LV pressure difference in patients with diastolic dysfunction: evaluation by color M-mode echocardiography.

21 January 2018

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Determinants of left ventricular early-diastolic lengthening velocity: independent contributions from left ventricular relaxation, restoring forces, and lengthening load.

21 January 2018

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Volume loading slows left ventricular isovolumic relaxation rate. Evidence of load-dependent relaxation in the intact dog heart

21 January 2018

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Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: a randomized clinical trial

21 January 2018

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Ranolazine improves diastolic dysfunction in isolated myocardium from failing human hearts--role of late sodium current and intracellular ion accumulation

21 January 2018

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Repolarization abnormalities in cardiomyocytes of dogs with chronic heart failure: role of sustained inward current

21 January 2018

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Age and hypertrophy related changes in contractile post-rest behavior and action potential properties in isolated rat myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00704.2013

10.1152/AJPHEART.00704.2013

21 January 2018

Identifiers

DOI

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6 February 2018

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6 February 2018