Multiple epsilon-promoter elements participate in the developmental control of epsilon-globin genes in transgenic mice (Q47892167)

6 February 2018

title

Multiple epsilon-promoter elements participate in the developmental control of epsilon-globin genes in transgenic mice (English)

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6 February 2018

author name string

Li Q

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6 February 2018

Blau CA

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6 February 2018

Clegg CH

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6 February 2018

Rohde A

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6 February 2018

Stamatoyannopoulos G

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6 February 2018

language of work or name

English

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publication date

1 July 1998

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6 February 2018

Journal of Biological Chemistry

published in

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6 February 2018

volume

273

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issue

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6 February 2018

page(s)

17361-17367

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6 February 2018

Human embryonic haemoglobins Gower 1 and Gower 2

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A developmentally stable chromatin structure in the human beta-globin gene cluster

21 January 2018

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A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus.

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Position-independent, high-level expression of the human beta-globin gene in transgenic mice

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A dominant control region from the human beta-globin locus conferring integration site-independent gene expression

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Autonomous developmental control of human embryonic globin gene switching in transgenic mice.

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Developmentally regulated and erythroid-specific expression of the human embryonic beta-globin gene in transgenic mice

21 January 2018

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Identification of a transcriptional silencer in the 5'-flanking region of the human epsilon-globin gene

21 January 2018

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Binding of erythroid and non-erythroid nuclear proteins to the silencer of the human epsilon-globin-encoding gene

21 January 2018

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Developmental regulation of the human embryonic beta-like globin gene is mediated by synergistic interactions among multiple tissue- and stage-specific elements

21 January 2018

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Developmental regulation of human gamma-globin genes in transgenic mice

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Position independence and proper developmental control of gamma-globin gene expression require both a 5' locus control region and a downstream sequence element

21 January 2018

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Binary transgenic mouse model for studying the trans control of globin gene switching: evidence that GATA-1 is an in vivo repressor of human epsilon gene expression

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Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants

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Coexpression of epsilon, G gamma and A gamma globin mRNA in embryonic red blood cells from a single copy beta-YAC transgenic mouse.

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Transcriptional role of a conserved GATA-1 site in the human epsilon-globin gene promoter

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A DNA-bending protein interacts with an essential upstream regulatory element of the human embryonic beta-like globin gene

21 January 2018

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Enhancer-dependent transcription of the epsilon-globin promoter requires promoter-bound GATA-1 and enhancer-bound AP-1/NF-E2

21 January 2018

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Essential role of NF-E2 in remodeling of chromatin structure and transcriptional activation of the epsilon-globin gene in vivo by 5' hypersensitive site 2 of the beta-globin locus control region

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A novel developmental regulatory motif required for stage-specific activation of the epsilon-globin gene and nuclear factor binding in embryonic erythroid cells

21 January 2018

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Phylogenetic footprinting reveals unexpected complexity in trans factor binding upstream from the epsilon-globin gene

21 January 2018

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Mutation of gene-proximal regulatory elements disrupts human epsilon-, gamma-, and beta-globin expression in yeast artificial chromosome transgenic mice

21 January 2018

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21 January 2018

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21 January 2018

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Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes

21 January 2018

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Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice

21 January 2018

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Dissection of the enhancer activity of beta-globin 5' DNase I-hypersensitive site 2 in transgenic mice

21 January 2018

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Human Embryonic Hæmoglobins

21 January 2018

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Predominance of hemoglobin Gower 1 in early human embryonic development

21 January 2018

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The beta-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner

21 January 2018

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Production of transgenic mice with yeast artificial chromosomes

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.273.28.17361

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6 February 2018

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6 February 2018