Communication pathways to and from the inner ear and their contributions to drug delivery. (Q47896229)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29277248%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

review article

1 reference

title

Communication pathways to and from the inner ear and their contributions to drug delivery (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29277248%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29277248%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

Keiko Hirose

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29277248%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

publication date

19 December 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29277248%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29277248%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

volume

362

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29277248%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

page(s)

25-37

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29277248%20AND%20SRC:MED&resulttype=core&format=json

Temporal bone histopathology of furosemide ototoxicity.

8 April 2020

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1 December 2018

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Improved Auditory Nerve Survival with Nanoengineered Supraparticles for Neurotrophin Delivery into the Deafened Cochlea

1 December 2018

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Perilymph pharmacokinetics of locally-applied gentamicin in the guinea pig.

1 December 2018

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Endolymph movement visualized with light sheet fluorescence microscopy in an acute hydrops model

1 December 2018

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Intracochlear Drug Injections through the Round Window Membrane: Measures to Improve Drug Retention.

1 December 2018

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Quantitative PCR analysis and protein distribution of drug transporter genes in the rat cochlea

1 December 2018

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1 December 2018

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1 December 2018

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Local treatment of the inner ear: a study of three different polymers aimed for middle ear administration

1 December 2018

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Hearing Loss and Otopathology Following Systemic and Intracerebroventricular Delivery of 2-Hydroxypropyl-Beta-Cyclodextrin.

1 December 2018

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Perilymph Kinetics of FITC-Dextran Reveals Homeostasis Dominated by the Cochlear Aqueduct and Cerebrospinal Fluid.

1 December 2018

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Efflux transporters in blood-brain interfaces of the developing brain

1 December 2018

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Macromolecular organization and fine structure of the human basilar membrane - RELEVANCE for cochlear implantation

1 December 2018

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Noise alters guinea pig's blood-labyrinth barrier ultrastructure and permeability along with a decrease of cochlear Claudin-5 and Occludin

1 December 2018

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Microperforations significantly enhance diffusion across round window membrane

1 December 2018

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Systemic lipopolysaccharide compromises the blood-labyrinth barrier and increases entry of serum fluorescein into the perilymph.

1 December 2018

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Water permeability of the mammalian cochlea: functional features of an aquaporin-facilitated water shunt at the perilymph-endolymph barrier.

1 December 2018

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Gentamicin concentration gradients in scala tympani perilymph following systemic applications.

1 December 2018

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Gentamicin administration on the stapes footplate causes greater hearing loss and vestibulotoxicity than round window administration in guinea pigs

1 December 2018

1 reference

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Dual origin of the epithelium of the mammalian middle ear.

1 December 2018

1 reference

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Hearing loss and hair cell death in mice given the cholesterol-chelating agent hydroxypropyl-β-cyclodextrin

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Inner ear tissue remodeling and ion homeostasis gene alteration in murine chronic otitis media

1 December 2018

1 reference

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Specific targeting of retrocochlear auditory pathway for optimal pharmacotherapy delivery using a mouse model

1 December 2018

1 reference

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Inflammatory cell trafficking across the blood-brain barrier: chemokine regulation and in vitro models

1 December 2018

1 reference

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Systemic aminoglycosides are trafficked via endolymph into cochlear hair cells

1 December 2018

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Functional activity mapping of rat auditory pathway after intratympanic manganese administration

1 December 2018

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Marker entry into vestibular perilymph via the stapes following applications to the round window niche of guinea pigs

1 December 2018

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Uptake of gentamicin by vestibular efferent neurons and superior olivary complex after transtympanic administration in guinea pigs.

1 December 2018

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Direct entry of gadolinium into the vestibule following intratympanic applications in Guinea pigs and the influence of cochlear implantation

1 December 2018

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Regulation of sodium transport in the inner ear.

1 December 2018

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Na+/K+-ATPase α1 Identified as an Abundant Protein in the Blood-Labyrinth Barrier That Plays an Essential Role in the Barrier Integrity

1 December 2018

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Principles of inner ear sustained release following intratympanic administration

1 December 2018

1 reference

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Distribution of dexamethasone and preservation of inner ear function following intratympanic delivery of a gel-based formulation.

1 December 2018

1 reference

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Induced endolymphatic flow from the endolymphatic sac to the cochlea in Ménière's disease

1 December 2018

1 reference

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Pericytes are required for blood-brain barrier integrity during embryogenesis

1 December 2018

1 reference

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Dose-dependent sustained release of dexamethasone in inner ear cochlear fluids using a novel local delivery approach

1 December 2018

1 reference

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Communication routes between intracranial spaces and inner ear: function, pathophysiologic importance and relations with inner ear diseases

1 December 2018

1 reference

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Trafficking of systemic fluorescent gentamicin into the cochlea and hair cells.

1 December 2018

1 reference

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Entry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: implications for local drug delivery in humans.

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Permeability of the round window membrane is influenced by the composition of applied drug solutions and by common surgical procedures

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Epithelial cell-cell junctions and plasma membrane domains

1 December 2018

1 reference

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Connexin30 deficiency causes instrastrial fluid-blood barrier disruption within the cochlear stria vascularis

1 December 2018

1 reference

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Perilymph/modiolar communication routes in the human cochlea

1 December 2018

1 reference

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Evolutionary changes in the cochlea and labyrinth: Solving the problem of sound transmission to the balance organs of the inner ear.

1 December 2018

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Osteoprotegrin knockout mice demonstrate abnormal remodeling of the otic capsule and progressive hearing loss

1 December 2018

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Perilymph sampling from the cochlear apex: a reliable method to obtain higher purity perilymph samples from scala tympani.

1 December 2018

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Inner ear drug delivery via a reciprocating perfusion system in the guinea pig.

1 December 2018

1 reference

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In vivo demonstration of the absorptive function of the middle ear epithelium

1 December 2018

1 reference

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Mononuclear phagocytes migrate into the murine cochlea after acoustic trauma

1 December 2018

1 reference

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Hearing impairment associated with spinal anesthesia

1 December 2018

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Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

1 December 2018

1 reference

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Cochlear aqueduct flow resistance depends on round window membrane position in guinea pigs

1 December 2018

1 reference

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Surface microstructure of the perilymphatic space: implications for cochlear implants and cell- or drug-based therapies.

1 December 2018

1 reference

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Responses of the endolymphatic sac to perilymphatic injections and withdrawals: evidence for the presence of a one-way valve.

1 December 2018

1 reference

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Round window pH manipulation alters the ototoxicity of systemic cisplatin

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Contamination of perilymph sampled from the basal cochlear turn with cerebrospinal fluid.

1 December 2018

1 reference

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Influence of pH on the ototoxicity of cisplatin: a round window application study

1 December 2018

1 reference

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Dynamics of inner ear pressure change caused by intracranial pressure manipulation in the guinea pig.

1 December 2018

1 reference

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Clinical aspects of round window membrane permeability under normal and pathological conditions

1 December 2018

1 reference

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Quantification of solute entry into cochlear perilymph through the round window membrane

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Expression of multidrug resistance protein 1 (MRP1) in the rat cochlea with special reference to the blood-inner ear barrier

1 December 2018

1 reference

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Transduction of the contralateral ear after adenovirus-mediated cochlear gene transfer

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Perspectives: biomedicine. The benefits of recycling

1 December 2018

1 reference

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Recent experimental and clinical findings retarding an interlabyrinthine connection

1 December 2018

1 reference

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Corticosteroid pharmacokinetics in the inner ear fluids: an animal study followed by clinical application

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Inner ear transgene expression after adenoviral vector inoculation in the endolymphatic sac.

1 December 2018

1 reference

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Dye-coupling of melanocytes with endothelial cells and pericytes in the cochlea of gerbils

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Longitudinal endolymph flow associated with acute volume increase in the guinea pig cochlea.

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Anatomy of the normal human cochlear aqueduct with functional implications

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Apical cochlear nerve exposed to perilymph in the gerbil and rat.

1 December 2018

1 reference

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Bone lining cells of the mammalian cochlea

1 December 2018

1 reference

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The fine structure of the cochlear plexus

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

The cochlear frequency map for the cat: labeling auditory-nerve fibers of known characteristic frequency

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Distribution of HRP in the inner ear after injection into the middle ear cavity

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Transport characteristics of the blood—Perilymph barrier

1 December 2018

1 reference

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A Contribution to the Physiology of the Perilymph Part I: The Origins of Perilymph

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Cation transport in the ampulla of the semicircular canal and in the endolymphatic sac.

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Comparative anatomy of cochlear blood vessels

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Perilymph composition in scala tympani of the cochlea: influence of cerebrospinal fluid.

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Effects of posture and age on tympanic membrane displacement measurements

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Calcium gradients in inner ear endolymph

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Middle ear effusion induced by various inflammatory mediators and neuropeptides. An experimental study in the rat.

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Fine structure of the intracochlear potential field. I. The silent current

1 December 2018

1 reference

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Atrophy of outer hair cell stereocilia and hearing loss in hydropic cochleae

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Gas composition and pressure in the middle ear: a model for the physiological steady state

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Evaluation of Procedures to Reduce Fluid Flow in the Fistulized Guinea-pig Cochlea

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

1 December 2018

1 reference

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Permeability changes of the blood-labyrinth barrier measured in vivo during experimental treatments.

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Protein profiles of perilymph and endolymph of the guinea pig

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Mechano-electrical transducer currents in hair cells of the cultured neonatal mouse cochlea

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Macromolecular transport by the middle ear and its lymphatic system

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

The fine structure of freeze-fractured intercellular junctions in the guinea pig inner ear

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

Ion transport in guinea pig cochlea. I. Potassium and sodium transport

1 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911243

The Effect of Cerebrospinal Fluid Pressure on Perilymphatic Flow in the Opened Cochlea

1 December 2018

1 reference

12 December 2020

Freeze-fracture aspects of the junctional complexes in the round window membrane

1 reference

12 December 2020

Radial communication between the perilymphatic scalae of the cochlea. II: Estimation by bolus injection of tracer into the sealed cochlea

1 reference

12 December 2020

Changes in Ca++ activity and DC potential in experimentally induced endolymphatic hydrops

1 reference

12 December 2020

Changes of the permeability of round window membrane in otitis media

1 reference

12 December 2020

Autonomic nerves and middle ear fluid production. An experimental study in the rat

1 reference

12 December 2020

Na and nonelectrolyte entry into inner ear fluids of the rat

1 reference

12 December 2020

Biochemical differences between perilymph, cerebrospinal fluid and blood plasma in the guinea pig

1 reference

12 December 2020

Blockage of the Cochlear Aqueduct

1 reference

12 December 2020

K, Cl, and H2O entry in endolymph, perilymph, and cerebrospinal fluid of the rat

1 reference

12 December 2020

Endolymph volume changes during osmotic dehydration measured by two marker techniques

1 reference

12 December 2020

Measurement of the mechanical compliance of the endolymphatic compartments in the guinea pig

1 reference

12 December 2020

Postural-induced changes in intracranial pressure evaluated non-invasively using the MMS-10 tympanic displacement analyser in healthy volunteers

1 reference

12 December 2020

Connection between the inner ear and the lymphatic system

1 reference

12 December 2020

Osteoprotegerin in the inner ear may inhibit bone remodeling in the otic capsule

1 reference

12 December 2020

Three-dimensional regular arrangement of the annular ligament of the rat stapediovestibular joint

1 reference

12 December 2020

Evidence of Gadolinium Distribution from the Endolymphatic Sac to the Endolymphatic Compartments of the Human Inner Ear

1 reference

12 December 2020

10.1016/J.HEARES.2017.12.010

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29277248%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29277248%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

PubMed publication ID

29277248

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29277248%20AND%20SRC:MED&resulttype=core&format=json