Activation of extracellular signal-regulated kinase mediates bombesin-induced mitogenic responses in prostate cancer cells (Q47746078)

5 February 2018

title

Activation of extracellular signal-regulated kinase mediates bombesin-induced mitogenic responses in prostate cancer cells (English)

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5 February 2018

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Dongmei Xiao

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5 February 2018

Xiangping Qu

series ordinal

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5 February 2018

H Christian Weber

series ordinal

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5 February 2018

publication date

1 October 2003

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5 February 2018

number of pages

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inferred from page(s)

published in

Cellular Signalling

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5 February 2018

volume

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5 February 2018

issue

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5 February 2018

page(s)

945-953

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5 February 2018

Mammalian bombesin receptors

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Calcium signaling in prostate cancer cells: evidence for multiple receptors and enhanced sensitivity to bombesin/GRP.

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Signal transduction pathways in the mitogenic response to G protein-coupled neuropeptide receptor agonists

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EGF receptor function is required in late G(1) for cell cycle progression induced by bombesin and bradykinin

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EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

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Bombesin and neuromedin B stimulate the activation of p42(mapk) and p74(raf-1) via a protein kinase C-independent pathway in Rat-1 cells

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Bombesin-induced pancreatic regeneration in pigs is mediated by p46Shc/p52Shc and p42/p44 mitogen-activated protein kinase upregulation.

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Bombesin activates MAP kinase in non-small cell lung cancer cells

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Neuroendocrine cells in tumour growth of the prostate

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Bombesin stimulates growth of human prostatic cancer cells in vitro

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7 January 2021

Presence of receptors for bombesin/gastrin-releasing peptide and mRNA for three receptor subtypes in human prostate cancers

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In situ hybridization for gastrin-releasing peptide receptor (GRP receptor) expression in prostatic carcinoma

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Inhibition of growth of androgen-independent DU-145 prostate cancer in vivo by luteinising hormone-releasing hormone antagonist Cetrorelix and bombesin antagonists RC-3940-II and RC-3950-II.

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Luteinizing hormone-releasing hormone antagonist Cetrorelix (SB-75) and bombesin antagonist RC-3940-II inhibit the growth of androgen-independent PC-3 prostate cancer in nude mice

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Effect of somatostatin analog RC-160 and bombesin/gastrin releasing peptide antagonist RC-3095 on growth of PC-3 human prostate-cancer xenografts in nude mice

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7 January 2021

Potentiation of the inhibitory effect of growth hormone-releasing hormone antagonists on PC-3 human prostate cancer by bombesin antagonists indicative of interference with both IGF and EGF pathways

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In vivo inhibition of PC-3 human androgen-independent prostate cancer by a targeted cytotoxic bombesin analogue, AN-215

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Characterization of high-affinity receptors for bombesin/gastrin releasing peptide on the human prostate cancer cell lines PC-3 and DU-145: internalization of receptor bound 125I-(Tyr4) bombesin by tumor cells

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7 January 2021

Bombesin specifically induces intracellular calcium mobilization via gastrin-releasing peptide receptors in human prostate cancer cells

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7 January 2021

Bombesin stimulates the motility of human prostate-carcinoma cells through tyrosine phosphorylation of focal adhesion kinase and of integrin-associated proteins

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7 January 2021

Activation of MAP kinases in growth responsive pancreatic cancer cells

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7 January 2021

New insights into the control of MAP kinase pathways

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7 January 2021

Bombesin and epidermal growth factor stimulate the mitogen-activated protein kinase through different pathways in Swiss 3T3 cells

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7 January 2021

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Carbachol-stimulated transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T(84) cells is mediated by intracellular Ca2+, PYK-2, and p60(src).

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7 January 2021

Reduced requirement of mitogen-activated protein kinase (MAPK) activity for entry into the S phase of the cell cycle in Swiss 3T3 fibroblasts stimulated by bombesin and insulin

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7 January 2021

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G protein-coupled receptors desensitize and down-regulate epidermal growth factor receptors in renal mesangial cells

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7 January 2021

Beta-adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases

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7 January 2021

Characterization of Ca2+ channels involved in ET-1-induced transactivation of EGF receptors

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Thrombin-induced p38 mitogen-activated protein kinase activation is mediated by epidermal growth factor receptor transactivation pathway

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7 January 2021

Distinct calcium-dependent pathways of epidermal growth factor receptor transactivation and PYK2 tyrosine phosphorylation in PC12 cells

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7 January 2021

The metalloprotease Kuzbanian (ADAM10) mediates the transactivation of EGF receptor by G protein-coupled receptors

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Src-dependent phosphorylation of the epidermal growth factor receptor on tyrosine 845 is required for zinc-induced Ras activation

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7 January 2021

Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway.

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7 January 2021

Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras.

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7 January 2021

beta 2-adrenergic receptor activates extracellular signal-regulated kinases (ERKs) via the small G protein rap1 and the serine/threonine kinase B-Raf

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7 January 2021

Activation of mitogen-activated protein kinase by the A(2A)-adenosine receptor via a rap1-dependent and via a p21(ras)-dependent pathway

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7 January 2021

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Identifiers

DOI

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5 February 2018

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5 February 2018