Transcription factor GATA-6 activates expression of gastroprotective trefoil genes TFF1 and TFF2. (Q47685190)

4 February 2018

title

Transcription factor GATA-6 activates expression of gastroprotective trefoil genes TFF1 and TFF2. (English)

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4 February 2018

author name string

E D Al-azzeh

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4 February 2018

P Fegert

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4 February 2018

N Blin

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4 February 2018

P Gött

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4 February 2018

publication date

1 February 2000

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4 February 2018

number of pages

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Biochimica et Biophysica Acta

inferred from page(s)

published in

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4 February 2018

volume

1490

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4 February 2018

issue

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4 February 2018

page(s)

324-332

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4 February 2018

Trefoil peptides: from structure to function

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Tracing the evolutionary origin of the TFF-domain, an ancient motif at mucous surfaces

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Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein

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Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor

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Trefoil peptide protection of intestinal epithelial barrier function: cooperative interaction with mucin glycoprotein

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Experimental ulceration leads to sequential expression of spasmolytic polypeptide, intestinal trefoil factor, epidermal growth factor and transforming growth factor alpha mRNAs in rat stomach.

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Human spasmolytic polypeptide is a cytoprotective agent that stimulates cell migration

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7 January 2021

Hepatocyte nuclear factor 3 (winged helix domain) activates trefoil factor gene TFF1 through a binding motif adjacent to the TATAA box.

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7 January 2021

Identification of a goblet cell-specific enhancer element in the rat intestinal trefoil factor gene promoter bound by a goblet cell nuclear protein

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Trefoil factor family (TFF)-domain peptides in the mouse: embryonic gastrointestinal expression and wounding response.

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Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiation

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Gastric DNA-binding proteins recognize upstream sequence motifs of parietal cell-specific genes

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A gut-to-pharynx/tail switch in embryonic expression of the Caenorhabditis elegans ges-1 gene centers on two GATA sequences.

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Transcriptional activation of H+/K+-ATPase genes by gastric GATA binding proteins

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GATA-6 DNA binding protein expressed in human gastric adenocarcinoma MKN45 cells

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7 January 2021

Regulated expression of GATA-6 transcription factor in gastric endocrine cells

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7 January 2021

Osmotic changes and ethanol modify TFF gene expression in gastrointestinal cell lines

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7 January 2021

GATA-6 induces p21(Cip1) expression and G1 cell cycle arrest

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7 January 2021

Selection of DNA binding sites for human transcriptional regulator GATA-6

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Trefoil peptide TFF2 (spasmolytic polypeptide) potently accelerates healing and reduces inflammation in a rat model of colitis

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7 January 2021

10.1016/S0167-4781(00)00013-0

Identifiers

DOI

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4 February 2018

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4 February 2018