Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second (Q47370705)

15 January 2018

title

Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second (English)

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15 January 2018

Corrigendum: Fibronectin-bound α5β1 integrins sense load and signal to reinforce adhesion in less than a second

corrigendum / erratum

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Nico Strohmeyer

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Mercedes Costell

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Reinhard Fässler

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15 January 2018

Mitasha Bharadwaj

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15 January 2018

Daniel J Müller

series ordinal

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15 January 2018

language of work or name

English

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publication date

6 November 2017

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15 January 2018

published in

Nature Materials

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15 January 2018

volume

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15 January 2018

issue

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15 January 2018

page(s)

1262-1270

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15 January 2018

Cell adhesion receptors in mechanotransduction

cites work

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β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

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Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

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Stretching single talin rod molecules activates vinculin binding

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Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

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Visualizing the mechanical activation of Src.

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Catch bonds in adhesion.

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Single-cell force spectroscopy

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The integrin expression profile modulates orientation and dynamics of force transmission at cell-matrix adhesions.

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Rigidity sensing and adaptation through regulation of integrin types.

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Cyclic mechanical reinforcement of integrin-ligand interactions

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Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin

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αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin.

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Rapid signal transduction in living cells is a unique feature of mechanotransduction.

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A mechanosensory complex that mediates the endothelial cell response to fluid shear stress

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Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction

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The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NMAT5023

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15 January 2018

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15 January 2018