Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy (Q47302520)

13 January 2018

title

Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy (English)

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13 January 2018

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13 January 2018

Nikolai Tupitsyn

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Yibin Kang

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13 January 2018

author name string

Hanqiu Zheng

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13 January 2018

Yangjin Bae

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13 January 2018

Sabine Kasimir-Bauer

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13 January 2018

Rebecca Tang

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13 January 2018

Jin Chen

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13 January 2018

Guangwen Ren

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13 January 2018

Min Yuan

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13 January 2018

Mark Esposito

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13 January 2018

Wenyang Li

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13 January 2018

Yong Wei

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13 January 2018

Minhong Shen

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13 January 2018

Klaus Pantel

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13 January 2018

Chadwick King

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13 January 2018

Jan Sun

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13 January 2018

Jodi Moriguchi

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13 January 2018

Helen Toni Jun

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13 January 2018

Angela Coxon

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13 January 2018

Brendan Lee

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13 January 2018

publication date

1 December 2017

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13 January 2018

published in

Cancer Cell

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13 January 2018

volume

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13 January 2018

issue

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13 January 2018

page(s)

731-747.e6

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13 January 2018

describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5729937/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Progress in adjuvant chemotherapy for breast cancer: an overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

The osteogenic niche promotes early-stage bone colonization of disseminated breast cancer cells

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

The notch ligand JAGGED1 as a target for anti-tumor therapy

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Acute myelogenous leukemia-induced sympathetic neuropathy promotes malignancy in an altered hematopoietic stem cell niche

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

MTDH-SND1 interaction is crucial for expansion and activity of tumor-initiating cells in diverse oncogene- and carcinogen-induced mammary tumors

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Dynamic changes in intracellular ROS levels regulate airway basal stem cell homeostasis through Nrf2-dependent Notch signaling

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistance

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone metastasis

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Endothelial cells promote the colorectal cancer stem cell phenotype through a soluble form of Jagged-1.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Cancer to bone: a fatal attraction

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Cis-interactions between Notch and Delta generate mutually exclusive signalling states

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

cis-Inhibition of Notch by endogenous Delta biases the outcome of lateral inhibition.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Rational targeting of Notch signaling in cancer

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Therapeutic potential of gamma-secretase inhibitors and modulators

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

AMG 706, an oral, multikinase inhibitor that selectively targets vascular endothelial growth factor, platelet-derived growth factor, and kit receptors, potently inhibits angiogenesis and induces regression in tumor xenografts

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

A pooled analysis of bone marrow micrometastasis in breast cancer

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Organ-selective chemoresistance in metastasis from human breast cancer cells: inhibition of apoptosis, genetic variability and microenvironment at the metastatic focus.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

A multigenic program mediating breast cancer metastasis to bone

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Antibody discovery: the use of transgenic mice to generate human monoclonal antibodies for therapeutics

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Molecular cytogenetic analysis of 11 new breast cancer cell lines

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5729937

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

2 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29232552

12 December 2020

inferred from PubMed ID database lookup

Crosstalk of Notch with p53 and p63 in cancer growth control

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29232552

12 December 2020

inferred from PubMed ID database lookup

Leukemia propagating cells rebuild an evolving niche in response to therapy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29232552

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.CCELL.2017.11.002

1 reference

13 January 2018

release_ds5zjv2zpfgoxipxcidntstsmq

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ds5zjv2zpfgoxipxcidntstsmq

24 November 2022

mapped directly with Wikidata item

PMC publication ID

5729937

0 references

1 reference

13 January 2018